MODIFIED HYBRID SILICA AEROGELS
    17.
    发明申请
    MODIFIED HYBRID SILICA AEROGELS 有权
    改性混合二氧化硅空气

    公开(公告)号:US20150065590A1

    公开(公告)日:2015-03-05

    申请号:US14536735

    申请日:2014-11-10

    Abstract: Disclosed and claimed herein are hybrid silica aerogels containing non-polymeric, functional organic materials covalently bonded at one or both ends to the silica network of the aerogels through a C—Si bond between a carbon atom of the organic material and a silicon atom of the aerogel network. Methods of their preparation are also disclosed.

    Abstract translation: 本文公开和要求保护的是混合二氧化硅气凝胶,其含有在一端或两端通过有机材料的碳原子与有机材料的硅原子之间的C-Si键在气凝胶的二氧化硅网络上共价结合的非聚合功能有机材料 气凝胶网络 还公开了它们的制备方法。

    Method of drying biological material
    18.
    发明授权
    Method of drying biological material 有权
    生物材料干燥方法

    公开(公告)号:US08877469B2

    公开(公告)日:2014-11-04

    申请号:US11701096

    申请日:2007-02-01

    Abstract: A method for producing foams containing biological materials is described. A solid or semi-solid paste is formed by combining biologically active material with a protecting agent in an aqueous solvent. The paste formed is allowed to set, and may optionally then be apportioned into the desired shape. The paste may be frozen to allow formation of ice crystals to act as porogens. Subsequently, the paste is exposed to travelling wave radiant energy under vacuum (t-REV) for drying. This causes the solvent to boil off, leaving dried material containing the biologically active material, the protecting agent, and a relatively low water content. Biologically active materials which can be used include cells, microbial cultures, live attenuated microbes, probiotics, yeasts, enzymes, vaccines, proteins, and any heat-sensitive biological material. By directing energy via a travelling wave through a sample, good control of temperature and process conditions can be achieved. The method provides an alternative to the conventional methods of particulate leaching or freeze drying.

    Abstract translation: 描述了生产含有生物材料的泡沫体的方法。 通过在水性溶剂中将生物活性物质与保护剂组合而形成固体或半固体糊状物。 允许形成的糊料固化,然后可任选地分配成所需的形状。 可以将糊状物冷冻以允许形成冰晶以充当致孔剂。 随后,将该糊剂暴露于真空下的行波辐射能(t-REV)以进行干燥。 这导致溶剂沸腾,留下含有生物活性物质的干燥物质,保护剂和相对较低的含水量。 可以使用的生物活性材料包括细胞,微生物培养物,活减毒微生物,益生菌,酵母,酶,疫苗,蛋白质和任何热敏生物材料。 通过将能量经由行波引导通过样品,可以实现温度和工艺条件的良好控制。 该方法提供了常规的微粒浸出或冷冻干燥方法的替代方案。

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