公开(公告)号：US20240264191A1

公开(公告)日：2024-08-08

申请号：US18107135

申请日：2023-02-08

Applicant: SiPhox, Inc.

Inventor： Azra Horowitz ,  Diedrik Vermeulen ,  Armando Paredes ,  Michael Dubrovsky

IPC: G01N35/10

CPC classification number: G01N35/1009 ,  G01N2035/1034

Abstract: An apparatus for actuating of fluids in a biosensor cartridge, the apparatus includes a microfluidic device, the microfluidic device includes a microfluidic circuit comprising at least a reservoir configured to contain at least a fluid and an active flow component in fluidic communication with the at least a reservoir, wherein the active flow component comprises a barrel and a plunger at a first position within the barrel, and an actuator configured to initiate an active flow process, wherein initiating the active flow process comprises accepting the plunger using a mechanical interface mechanically communicated to the actuator and moving the plunger within the barrel from the first position to a second position based on predetermined flow properties, and flow the at least a fluid unidirectionally as a function of the active flow process.

公开(公告)号：US20240255536A1

公开(公告)日：2024-08-01

申请号：US17997646

申请日：2021-09-13

Applicant: PUKYONG NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION

Inventor： Joong Ho SHIN ,  Tran Huy LE THANG

IPC: G01N35/10 ,  G01N35/00

CPC classification number: G01N35/1004 ,  G01N35/1009 ,  G01N2035/00356

Abstract: Provided are a nucleic acid extraction module and a nucleic acid test system including the same. A nucleic acid extraction module according to an embodiment of the present invention includes an extraction base in which a nucleic acid attachment member is disposed and a first flow path connected to one side of the nucleic acid attachment member and a second flow path connected to the other side of the nucleic acid attachment member are formed, an injection needle having a hollow shape, protruding from one side of the extraction base, and connected to the first flow path, and a discharge needle having a hollow shape, protruding from the other side of the extraction base, and connected to the second flow path.

公开(公告)号：US20240255412A1

公开(公告)日：2024-08-01

申请号：US18633224

申请日：2024-04-11

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Kalyan Handique ,  Austin Payne ,  Vishal Sharma ,  Kyle Gleason ,  Priyadarshini Gogoi ,  Karthik Ganesan ,  Brian Boniface ,  William Chow

IPC: G01N15/14 ,  B01L3/00 ,  B01L3/02 ,  C12M1/00 ,  G01N1/20 ,  G01N1/28 ,  G01N1/40 ,  G01N15/01 ,  G01N15/10 ,  G01N15/1433 ,  G01N15/149 ,  G01N35/00 ,  G01N35/10 ,  G06V10/141 ,  G06V10/145 ,  G06V10/147 ,  G06V20/69

CPC classification number: G01N15/1484 ,  B01L3/502715 ,  B01L3/502761 ,  C12M47/04 ,  G01N1/20 ,  G01N1/28 ,  G01N1/40 ,  G01N1/405 ,  G01N1/4077 ,  G01N15/1433 ,  G01N35/00029 ,  G01N35/1011 ,  G06V10/141 ,  G06V10/145 ,  G06V10/147 ,  G06V20/69 ,  B01L3/021 ,  B01L3/502746 ,  B01L2200/0652 ,  B01L2200/0668 ,  B01L2300/0636 ,  B01L2300/0654 ,  B01L2300/0672 ,  B01L2300/0816 ,  B01L2300/0819 ,  B01L2300/0848 ,  B01L2300/0877 ,  B01L2300/168 ,  B01L2400/086 ,  G01N15/01 ,  G01N2015/1006 ,  G01N15/149 ,  G01N2035/00158 ,  G01N2035/1039

Abstract: A system and method for isolating and analyzing single cells, including: a substrate having a broad surface; a set of wells defined at the broad surface of the substrate, and a set of channels, defined by the wall, that fluidly couple each well to at least one adjacent well in the set of wells; and fluid delivery module defining an inlet and comprising a plate, removably coupled to the substrate, the plate defining a recessed region fluidly connected to the inlet and facing the broad surface of the substrate, the fluid delivery module comprising a cell capture mode.

公开(公告)号：US12050232B2

公开(公告)日：2024-07-30

申请号：US17567041

申请日：2021-12-31

Applicant: Instrumentation Laboratory Company

Inventor： Chris Christoff ,  Joshua A. Shreve ,  Reed Hebert ,  Benjamin Newton

IPC: G01N35/10 ,  B01L7/00 ,  G01N35/00

CPC classification number: G01N35/1009 ,  G01N35/1002 ,  B01L7/525 ,  G01N2035/00425

Abstract: Systems and methods for probe tip heating are disclosed. An exemplary system for probe tip heating can include an enclosure enclosing a probe tip, a heating device, and a fan. The probe tip can be configured to access an internal volume of a stoppered container and to aspirate or dispense a material from or to the internal volume of the stoppered container. The heating device can be configured to heat air circulating within the enclosure. The fan can be positioned to circulate air within the enclosure to heat the tip of the probe.

公开(公告)号：US20240248109A1

公开(公告)日：2024-07-25

申请号：US18533708

申请日：2023-12-08

Applicant: CANON MEDICAL SYSTEMS CORPORATION

Inventor： Yoshihiro JIFUKU ,  Shohei KAWASHIMA ,  Tamaki HONDA ,  Masakazu KITAMURA ,  Gaku UENO

IPC: G01N35/10

CPC classification number: G01N35/1004

Abstract: An automatic analyzer includes a probe, a cleaner, and a controller. The probe includes a detector for detecting a contact with a liquid. The probe sucks and discharges the liquid. The cleaner cleans an outer wall of the probe with a cleaning fluid. The controller causes the detector to perform a detection during cleaning by the cleaner, and judges a state of the cleaner based on a result of the detection.

公开(公告)号：US12044691B2

公开(公告)日：2024-07-23

申请号：US16971658

申请日：2019-02-27

Applicant: Eppendorf SE

Inventor： Markus Lapczyna ,  Uwe Dunker ,  Burkhardt Reichmuth ,  Maik Radke

IPC: G01N35/10 ,  B01L3/02 ,  B01L9/00 ,  G01N35/00 ,  G01N35/04

CPC classification number: G01N35/1011 ,  G01N35/0099 ,  B01L3/021 ,  B01L9/54 ,  B01L2200/025 ,  B01L2200/148 ,  B01L2300/0627 ,  G01N2035/00811 ,  G01N2035/0093 ,  G01N2035/0494 ,  G01N2035/1013 ,  G01N2035/1048 ,  G05B2219/50133

Abstract: A measuring apparatus usable in a liquid handling apparatus, and method, for detecting a deformed pipetting container using a first and a second measuring device, the measuring apparatus being configured to determine the position of an end region of the pipetting container as a f unction of a position of a measurement support section of the pipetting container as relative position data in a data storage device, so that subsequently the position of the end region of the pipetting container can be determined by measuring the position of the measurement support section and from the relative position data.

公开(公告)号：US12038355B2

公开(公告)日：2024-07-16

申请号：US17144093

申请日：2021-01-07

Applicant: Precision Planting LLC

Inventor： Todd Swanson ,  Dale Koch ,  Reid Harman

IPC: B01D21/26 ,  A01C23/00 ,  B01D19/00 ,  B01D29/11 ,  B01F23/53 ,  B01F23/80 ,  B01F25/30 ,  B01F25/54 ,  B01F27/1125 ,  B01F27/808 ,  B01F27/906 ,  B01F35/00 ,  B01F35/10 ,  B01F35/21 ,  B01F35/45 ,  B04B5/04 ,  F04B43/06 ,  G01G17/04 ,  G01N1/08 ,  G01N1/38 ,  G01N1/40 ,  G01N21/05 ,  G01N21/25 ,  G01N21/78 ,  G01N33/24 ,  G01N35/00 ,  G01N35/10 ,  G05B15/02 ,  B01F23/50 ,  B01F101/00 ,  B01F101/23

CPC classification number: G01N1/08 ,  A01C23/007 ,  B01D19/00 ,  B01D21/262 ,  B01D29/112 ,  B01F23/53 ,  B01F23/807 ,  B01F23/808 ,  B01F25/30 ,  B01F25/54 ,  B01F27/11253 ,  B01F27/808 ,  B01F27/906 ,  B01F35/1452 ,  B01F35/187 ,  B01F35/2117 ,  B01F35/453 ,  B04B5/0421 ,  F04B43/06 ,  G01G17/04 ,  G01N1/38 ,  G01N1/4055 ,  G01N1/4077 ,  G01N21/05 ,  G01N21/251 ,  G01N21/78 ,  G01N33/24 ,  G01N35/00584 ,  G01N35/1004 ,  G01N35/1095 ,  G05B15/02 ,  B01D2201/4092 ,  B01F23/581 ,  B01F2101/005 ,  B01F2101/23 ,  G01N2001/4061 ,  G01N2001/4083 ,  G01N2001/4088 ,  G01N2033/245 ,  G01N2035/00188 ,  G01N2035/00475 ,  G01N2035/00495 ,  G01N2035/00514

Abstract: An automated computer-controlled sampling system and related methods for collecting, processing, and analyzing agricultural samples for various chemical properties such as plant available nutrients. The sampling system allows multiple samples to be processed and analyzed for different analytes or chemical properties in a simultaneous concurrent or semi-concurrent manner. Advantageously, the system can process soil samples in the “as collected” condition without drying or grinding. The system generally includes a sample preparation sub-system which receives soil samples collected by a probe collection sub-system and produces a slurry (i.e. mixture of soil, vegetation, and/or manure and water), and a chemical analysis sub-system which processes the prepared slurry samples for quantifying multiple analytes and/or chemical properties of the sample. The sample preparation and chemical analysis sub-systems can be used to analyze soil, vegetation, and/or manure samples.

公开(公告)号：US20240230693A1

公开(公告)日：2024-07-11

申请号：US18558412

申请日：2022-03-01

Applicant: HITACHI HIGH-TECH CORPORATION

Inventor： Hajime KATO ,  Yoichiro SUZUKI ,  Tetsuji KAWAHARA ,  Gorou YOSHIDA ,  Hisashi YABUTANI

IPC: G01N35/00 ,  G01N35/10

CPC classification number: G01N35/00623 ,  G01N35/1002 ,  G01N2035/00554

Abstract: An automatic chemical analyzer, maintenance kit, and maintenance method capable of, even in a case where a problem of the automatic chemical analyzer occurs, clarifying a cause of the problem in a user site and coping with the problem without collecting a device or a component. The automatic chemical analyzer maintenance kit is connectable to an automatic chemical analyzer including a reaction vessel for accommodating at least a pipetted specimen and a reagent, and a stirring mechanism including a piezoelectric element that irradiates the reaction vessel with ultrasonic waves. The piezoelectric element includes a plurality of divided electrodes. The automatic chemical analyzer maintenance kit measures, for each of the divided electrodes, an absolute value of an impedance of the piezoelectric element and a phase difference between a voltage applied to the divided electrode and a current, and determines if there is an abnormality an electrode based on a measurement result.

公开(公告)号：US12031984B2

公开(公告)日：2024-07-09

申请号：US17511975

申请日：2021-10-27

Applicant: CHINA AGRICULTURAL UNIVERSITY

Inventor： Nan Cheng ,  Xiaoyun He ,  Wentao Xu ,  Kunlun Huang ,  Yunbo Luo ,  Qian Zhang ,  Qingliang Liu

IPC: G01N33/543 ,  G01N35/10

CPC classification number: G01N33/54388 ,  G01N33/54306 ,  G01N2035/1088

Abstract: A detection device using a lateral flow strip for detection and a detection method thereof are provided, which relates to the technical field of a detection device using a lateral flow strip. An upper rotor, a middle rotor and a lower rotor are respectively provided with upper paddle(s), middle paddle(s) and lower paddle(s) along respective circumferential directions. Each upper paddle is provided with a test tube with openings at both ends thereof for placing the lateral flow strip. The middle paddle blocks a bottom one of the openings of the test tube. Each lower paddle is provided with a sample tube for placing sample solution. The bottom opening of the test tube is opposite to a top opening of the sample tube up and down.

公开(公告)号：US20240219415A1

公开(公告)日：2024-07-04

申请号：US18288789

申请日：2023-01-18

Applicant: Gen-Probe Incorporated

Inventor： Rolf SILBERT ,  HongRan PENG

IPC: G01N35/04 ,  G01N35/00 ,  G01N35/10

CPC classification number: G01N35/04 ,  G01N35/1011 ,  G01N2035/00326

Abstract: A jig assembly for connecting first and second consoles with predefined relative positioning includes first and second positioning pins attached or attachable to the first console and a positioning connection bracket attached or attachable to the second console and including a longitudinal span and first and second transverse legs including first and second pin recesses at respective free ends thereof. The first and second pin recesses receive the first and second positioning pins, respectively, when the first and second consoles are moved laterally toward each other. The first and second transverse legs may be attached to the first console with a first and second leg attachment brackets, respectively. The first and second positing pins and the first and second leg attachment brackets may be fixed with respect to the first console by attachment to a mounting rail that is fixed to the first console.