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1.发明申请公开(公告)号：US20190269316A1
公开(公告)日：2019-09-05
申请号：US16416047
申请日：2019-05-17
IPC分类号： A61B3/00 , A61B5/0496 , A61N1/36
摘要： The invention is a method of automatically adjusting a visual prosthesis electrode array to the neural characteristics of an individual patient. By recording electrically evoked responses to a predetermined input stimulus, one can alter that input stimulus to the needs of an individual patient. A minimum input stimulus is applied to a patient, followed by recording an electrically evoked response to the input stimulus. By gradually increasing stimulus levels, one can determine the minimum input that creates a neural response, thereby identifying the threshold stimulation level. One can further determine a maximum level by increasing stimulus until a predetermined maximum neural response is obtained.
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公开(公告)号：US10549096B2
公开(公告)日：2020-02-04
申请号：US15845000
申请日：2017-12-18
发明人： Robert J. Greenberg , Neil H. Talbot , Proyag Datta , Dustin Tobey , David Daomin Zhou , Jessy Dorn
摘要： The present invention is a flexible circuit electrode array for neural stimulation including a polymer base layer, a metal trace layer on the polymer base layer, and a polymer top layer on the metal traces layer, where the metal trace layer forms at least one electrode made of multiple smaller common electrodes connected by electrical traces.
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公开(公告)号：US20180243561A1
公开(公告)日：2018-08-30
申请号：US15967393
申请日：2018-04-30
发明人： Robert J. Greenberg , Arup Roy
CPC分类号： A61N1/36046 , A61N1/0543 , A61N1/37247
摘要： The present invention is an improved visual prosthesis including a video processing unit with user controls optimized for use by blind individuals. The controls include easily identifiable shapes. The controls are programmable to provide improved usability with a simple tactile interface.
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公开(公告)号：US10052482B2
公开(公告)日：2018-08-21
申请号：US15789136
申请日：2017-10-20
CPC分类号： A61N1/36046 , A61N1/0543 , A61N1/37247 , G06F19/3481 , G16H20/40 , G16H40/63
摘要： The present invention is an improved spatial fitting and training system for a visual prosthesis. The system of the present invention maps projected locations of percepts, where a person perceives a percept from a visual prosthesis to the intended location of the percepts. The projected location may vary over time. These test results can be used to correct a visual prosthesis or spatially map the visual prosthesis.
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公开(公告)号：US09931507B2
公开(公告)日：2018-04-03
申请号：US15207425
申请日：2016-07-11
发明人： Robert J. Greenberg , Jerry Ok , Jordan Neysmith , Kevin Wilkin , Neil Hamilton Talbot , Da-Yu Chang
CPC分类号： A61N1/36046 , A61N1/0543 , A61N1/375 , A61N1/3758 , A61N1/3787 , H01L2224/16227 , H01L2224/32225 , H01L2224/73253 , H01L2924/15311 , H01L2924/16251 , H01L2924/19104 , H01L2924/19107
摘要： The present invention is an improved hermetic package for a retinal prosthesis implanted in the human body. The retinal prosthesis includes a flexible circuit electrode array suitable to stimulate the retina while connected to a hermetic package on the outside of the eye, the hermetic package including a cover and a base where the cover is bonded to the base such that the cover and base form the hermetic package.
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公开(公告)号：US09821160B2
公开(公告)日：2017-11-21
申请号：US15174349
申请日：2016-06-06
CPC分类号： A61N1/36046 , A61N1/0543 , A61N1/37223
摘要： The present invention is a new configuration for the external portion of a visual prosthesis in the form of a visor or glasses, including a frame supported by a user's nose and ears. The video processing unit is adapted to be connected by temple portions of the visor and rest on the user's upper back behind the user's neck, or behind the user's head. Controls for the video processor are on one or both temple portions of the visor.
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公开(公告)号：US20170203097A1
公开(公告)日：2017-07-20
申请号：US15475788
申请日：2017-03-31
CPC分类号： A61N1/0543 , A61N1/36046 , H05K1/036 , H05K1/0393 , H05K1/118 , H05K3/0014 , H05K2201/05 , H05K2201/053 , H05K2201/09063 , H05K2201/09409 , Y10T29/49002 , Y10T29/49117 , Y10T29/49155 , Y10T29/49156 , Y10T29/49158 , Y10T29/49174 , Y10T29/49176
摘要： The present invention provides a flexible circuit electrode array adapted for neural stimulation, comprising: a polymer base layer; metal traces deposited on the polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on the polymer base layer and the metal traces at least one tack opening. The present invention provides further a method of making a flexible circuit electrode array comprising depositing a polymer base layer; depositing metal on the polymer base layer; patterning the metal to form metal traces; depositing a polymer top layer on the polymer base layer and the metal traces; and preparing at least one tack opening.
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公开(公告)号：US20170065817A1
公开(公告)日：2017-03-09
申请号：US15357909
申请日：2016-11-21
发明人： Kelly H. McClure , Richard A. Castro , Arup Roy , Scott Loftin , Rongqing Dai , Robert J. Greenberg , Sumit Yadav
CPC分类号： A61N1/36046 , A61F9/08 , A61N1/37229 , A61N1/37252
摘要： The present invention is a wireless transmission system for a prosthetic apparatus including a mounting system to be worn on a body, a wound wire transmission coil mounted to the mounting system and sending a stimulation signal, an implantable receiving coil receiving the stimulation signal and connected to a hermetic electronics package, an implantable telemetry transmitting coil connected to the hermetic electronics package, and a telemetry receiving coil printed on a printed circuit board, mounted to the mounting system and receiving the telemetry signal.
摘要翻译： 本发明是一种用于假体装置的无线传输系统，其包括要佩戴在身体上的安装系统，安装到安装系统并发送刺激信号的缠绕线传输线圈，接收刺激信号的可植入接收线圈并连接到 连接到密封电子封装的密封电子封装，可植入遥测传输线圈和印刷在印刷电路板上的遥测接收线圈，安装到安装系统并接收遥测信号。
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公开(公告)号：US20160317811A1
公开(公告)日：2016-11-03
申请号：US14854916
申请日：2015-09-15
发明人： Robert J. Greenberg , Arup Roy , Avraham I. Caspi , Uday Patel , Mark D. Welch
摘要： Systems and methods for detecting and displaying obstacles to visually impaired persons are disclosed. Images from a captured scene are analyzed to detect obstacles. A V-Disparity algorithm is employed to detect the ground plane and remove it from the images, thereby enhancing the capacity of retinal implants to display only obstacles. The system includes cameras to capture images; a processor with memory to detect obstacles in the captured images, to remove a ground plane, and to calculate a map of pixels representing the obstacles; and a retinal implant configured to receive the map of pixels and display the obstacles to a system user by electrically stimulating retinal nerves. The method includes synchronizing captured images and calculating a disparity map between the captured images to detect obstacles and remove a ground plane from processed images. A map of pixels representing the obstacle is transmitted to a retinal implant. Depth information may derive from stereo cameras, a time of flight camera or a structured light camera.
摘要翻译： 公开了用于检测和显示障碍物的障碍物的系统和方法。 分析捕获场景中的图像以检测障碍物。 采用V-Disparity算法来检测地面并从图像中去除，从而增强视网膜植入物仅显示障碍物的能力。 该系统包括拍摄图像的相机; 具有存储器的处理器，用于检测所捕获的图像中的障碍物，以去除接地平面，并计算表示障碍物的像素的图; 以及视网膜植入物，被配置为接收像素的图并且通过电刺激视网膜神经将障碍物显示给系统用户。 该方法包括同步捕获的图像并计算所捕获的图像之间的视差图，以检测障碍物并从处理的图像中移除接地平面。 表示障碍物的像素的图被发送到视网膜植入物。 深度信息可以来自立体相机，飞行时间相机或结构光照相机。
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10.发明申请Biocompatible Bonding Method and Electronics Package Suitable for Implantation 有权生物相容性接合方法和适用于植入的电子封装公开(公告)号：US20150296628A1
公开(公告)日：2015-10-15
申请号：US14516476
申请日：2014-10-16
IPC分类号： H05K3/18 , H05K3/32 , H05K3/30 , H05K1/02 , H05K3/46 , H05K13/04 , H05K1/11 , A61N1/36 , H05K3/10
CPC分类号： A61N1/3758 , A61N1/0543 , A61N1/36046 , A61N1/375 , H01L21/563 , H01L23/49827 , H01L23/49838 , H01L23/4985 , H01L24/81 , H01L2224/0557 , H01L2224/05571 , H01L2224/05573 , H01L2224/13169 , H01L2224/13178 , H01L2224/16225 , H01L2224/16227 , H01L2224/32225 , H01L2224/73204 , H01L2224/81469 , H01L2224/81478 , H01L2224/81815 , H01L2924/00014 , H01L2924/01019 , H01L2924/01046 , H01L2924/01077 , H01L2924/01078 , H01L2924/01079 , H01L2924/14 , H01L2924/1461 , H05K1/028 , H05K1/0306 , H05K1/09 , H05K1/111 , H05K1/113 , H05K1/115 , H05K1/189 , H05K3/10 , H05K3/188 , H05K3/305 , H05K3/321 , H05K3/328 , H05K3/3436 , H05K3/361 , H05K3/4015 , H05K3/4038 , H05K3/4084 , H05K3/423 , H05K3/4644 , H05K3/4652 , H05K3/4691 , H05K13/0469 , H05K2201/09127 , H05K2201/1028 , H05K2201/10287 , H05K2201/10295 , H05K2201/10977 , H05K2203/05 , H05K2203/06 , H05K2203/0733 , H05K2203/09 , H05K2203/107 , H05K2203/1446 , H01L2924/00 , H01L2224/05599
摘要： The invention is directed to a method of bonding a hermetically sealed electronics package to an electrode or a flexible circuit and the resulting electronics package, that is suitable for implantation in living tissue, such as for a retinal or cortical electrode array to enable restoration of sight to certain non-sighted individuals. The hermetically sealed electronics package is directly bonded to the flex circuit or electrode by electroplating a biocompatible material, such as platinum or gold, effectively forming a plated rivet-shaped connection, which bonds the flex circuit to the electronics package. The resulting electronic device is biocompatible and is suitable for long-term implantation in living tissue.
摘要翻译： 本发明涉及一种将气密密封的电子封装结合到电极或柔性电路的方法以及所得到的电子封装，其适于植入生物组织，例如用于视网膜或皮质电极阵列，以使视力恢复 对某些无意识的个人。 密封电子封装通过电镀生物相容性材料（例如铂或金）直接结合到柔性电路或电极上，有效地形成电镀铆钉形连接，其将柔性电路连接到电子封装。 所得到的电子装置是生物相容的并且适合长期植入生物体组织。
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