公开(公告)号：US20040214717A1

公开(公告)日：2004-10-28

申请号：US10850585

申请日：2004-05-20

Applicant: Symyx Technologies, Inc.

Inventor： Oliver Brummer ,  Gary M. Diamond ,  Christopher Goh ,  Anne M. LaPointe ,  Margarete K. Leclerc ,  James Longmire ,  James A.W. Shoemaker

IPC: C08F004/06 ,  B01J031/00

CPC classification number: C08F210/02 ,  C07D249/06 ,  C07F7/00 ,  C07F7/003 ,  C08F4/65908 ,  C08F4/65912 ,  C08F4/659 ,  C08F4/64 ,  C08F212/08 ,  C08F2500/03

Abstract: Metal-ligand complexes that are useful as precursors to catalysts for the polymerization of olefins are provided. Certain of the catalysts are particularly effective at polymerizing ethylene and styrene into copolymers having novel properties, including a low molecular weight and close comparison between vinyl and methyl end groups.

Abstract translation: 提供了可用作烯烃聚合催化剂前体的金属 - 配体络合物。 某些催化剂特别有效地将乙烯和苯乙烯聚合成具有新特性的共聚物，包括低分子量和乙烯基和甲基端基之间的紧密比较。

公开(公告)号：US20040155668A1

公开(公告)日：2004-08-12

申请号：US10772522

申请日：2004-02-05

Applicant: Symyx Technologies, Inc.

Inventor： Damian A. Hajduk ,  Eric D. Carlson ,  J. Christopher Freitag ,  Oleg Kolosov ,  James R. Engstrom ,  Adam Safir ,  Ravi Srinivasan ,  Leonid Matsiev

IPC: G01R027/26

CPC classification number: G01N3/10 ,  B01J2219/00274 ,  B01J2219/00315 ,  B01J2219/00364 ,  B01J2219/00373 ,  B01J2219/00477 ,  B01J2219/00495 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00621 ,  B01J2219/00653 ,  B01J2219/00659 ,  B01J2219/00675 ,  B01J2219/00677 ,  B01J2219/00689 ,  B01J2219/00691 ,  B01J2219/00707 ,  B01J2219/00716 ,  B01J2219/00722 ,  B01J2219/00745 ,  B01J2219/0075 ,  B01J2219/00754 ,  B82Y30/00 ,  C40B40/14 ,  C40B40/18 ,  C40B50/14 ,  C40B60/14 ,  G01N3/18 ,  G01N2203/0016 ,  G01N2203/0252 ,  G01N2203/0254 ,  G01N2203/0258 ,  G01N2203/0617 ,  G01N2203/0623 ,  G01N2203/0641

Abstract: A method for high throughput mechanical property testing of materials libraries using capacitance. The method monitors the responses of a plurality of samples on a substrate to a force induced by a capacitor.

Abstract translation: 一种使用电容的材料库的高通量力学性能测试方法。 该方法将衬底上的多个样品的响应监测为由电容器引起的力。

公开(公告)号：US20040151641A1

公开(公告)日：2004-08-05

申请号：US10764217

申请日：2004-01-23

Applicant: SYMYX TECHNOLOGIES, INC.

Inventor： Lynn Van Erden ,  William H. Chandler JR.

IPC: B01J019/00

CPC classification number: B01L3/5025 ,  B01J3/04 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00308 ,  B01J2219/0031 ,  B01J2219/00315 ,  B01J2219/00335 ,  B01J2219/00337 ,  B01J2219/00418 ,  B01J2219/00423 ,  B01J2219/00477 ,  B01J2219/00585 ,  B01J2219/00601 ,  B01J2219/00704 ,  B01J2219/0072 ,  B01J2219/00736 ,  G01N35/028

Abstract: An apparatus and method for synthesis and screening of materials are disclosed. According to one aspect of the present invention, a parallel batch reactor for effecting chemical reactions includes a pressure chamber, and a plurality of reaction wells. Each of the reaction wells is in isolatable fluid communication with the pressure chamber such that during a first pressurizing stage of operation, each of the reaction wells can be simultaneously pressurized through common fluid communication with the pressure chamber, and such that during a second reaction stage of operation, each of the reaction wells can be fluidically isolated from at least one other of said plurality of reaction wells.

Abstract translation: 公开了一种合成和筛选材料的装置和方法。 根据本发明的一个方面，用于实现化学反应的并行间歇反应器包括压力室和多个反应孔。 每个反应井与压力室可分离流体连通，使得在第一加压阶段期间，每个反应井可以通过与压力室的常见流体连通同时加压，并且使得在第二反应阶段 每个反应孔可以与所述多个反应孔中的至少另一个的流体分离。

公开(公告)号：US20040074303A1

公开(公告)日：2004-04-22

申请号：US10686444

申请日：2003-10-15

Applicant: Symyx Technologies, Inc

Inventor： Leonid Matsiev ,  James Bennett ,  Eric McFarland

IPC: G01H013/00 ,  G01H003/04

CPC classification number: G01H13/00 ,  B01J2219/00704 ,  G01N9/002 ,  G01N9/34 ,  G01N11/16 ,  G01N29/022 ,  G01N29/036 ,  G01N29/30 ,  G01N29/348 ,  G01N29/42 ,  G01N29/4418 ,  G01N29/4427 ,  G01N29/4436 ,  G01N2009/006 ,  G01N2291/014 ,  G01N2291/0224 ,  G01N2291/0255 ,  G01N2291/0256 ,  G01N2291/02818 ,  G01N2291/0422 ,  G01N2291/0423 ,  G01N2291/0427 ,  G10K11/02

Abstract: A method and apparatus for measuring properties of a liquid composition includes a mechanical resonator, such as a cantilever, connected to a measurement circuit. The mechanical resonator can be covered with a coating to impart additional special detection propertied to the resonator, and multiple resonators can be attached together as a single sensor to obtain multiple frequency responses. The invention is particularly suitable for combinatorial chemistry applications, which require rapid analysis of chemical properties for screening.

公开(公告)号：US20040073042A1

公开(公告)日：2004-04-15

申请号：US10650256

申请日：2003-08-27

Applicant: Symyx Technologies, Inc.

Inventor： Dominique Charmot ,  Han-Ting Chang ,  Victor Nava-Salgado

IPC: C07F009/02 ,  C07C337/00

CPC classification number: C07D295/24 ,  C07C329/16 ,  C07C2601/14 ,  C07D207/46 ,  C07D209/30 ,  C07D291/06 ,  C08F2/38 ,  C08F293/005

Abstract: Control agents that have an oxygen-nitrogen bond covalently bonded to a thiocarbonyl moiety are provided for living-type free radical polymerization of a wide variety of monomers, particularly vinyl monomers.

Abstract translation: 具有共价键合到硫代羰基部分上的氧 - 氮键的对照试剂被提供用于多种单体，特别是乙烯基单体的活性型自由基聚合。

公开(公告)号：US20040023302A1

公开(公告)日：2004-02-05

申请号：US10392238

申请日：2003-03-18

Applicant: Symyx Technologies, Inc.

Inventor： William B. Archibald ,  Marc D. Hornbostel

IPC: H01L021/00 ,  G01N033/53 ,  G01N033/543

CPC classification number: G01N21/55 ,  B01D15/265 ,  B01D15/325 ,  B01D15/34 ,  B01J19/0046 ,  B01J19/26 ,  B01J2219/00274 ,  B01J2219/00283 ,  B01J2219/00308 ,  B01J2219/0031 ,  B01J2219/00313 ,  B01J2219/00315 ,  B01J2219/00317 ,  B01J2219/00335 ,  B01J2219/00337 ,  B01J2219/00344 ,  B01J2219/00351 ,  B01J2219/00364 ,  B01J2219/00378 ,  B01J2219/0043 ,  B01J2219/00443 ,  B01J2219/00452 ,  B01J2219/00495 ,  B01J2219/00497 ,  B01J2219/005 ,  B01J2219/00511 ,  B01J2219/00515 ,  B01J2219/0052 ,  B01J2219/00527 ,  B01J2219/00536 ,  B01J2219/00583 ,  B01J2219/00585 ,  B01J2219/00587 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00653 ,  B01J2219/00659 ,  B01J2219/00675 ,  B01J2219/00689 ,  B01J2219/00691 ,  B01J2219/00702 ,  B01J2219/00704 ,  B01J2219/00707 ,  B01J2219/00722 ,  B01J2219/00738 ,  B01J2219/00745 ,  B01J2219/00747 ,  B01J2219/0075 ,  B01J2219/00752 ,  B01J2219/00754 ,  B82Y30/00 ,  C40B30/08 ,  C40B40/00 ,  C40B40/14 ,  C40B40/18 ,  C40B50/14 ,  C40B60/12 ,  C40B60/14 ,  G01J3/28 ,  G01N15/0205 ,  G01N21/3563 ,  G01N21/8422 ,  G01N29/036 ,  G01N29/0609 ,  G01N29/2418 ,  G01N29/348 ,  G01N33/44 ,  G01N35/085 ,  G01N2015/0288 ,  G01N2015/0294 ,  G01N2021/3595 ,  G01N2291/106

Abstract: This invention discloses methods, materials, and devices for making and screening combinatorial libraries to identify semi-conducting and thermoelectric materials. The disclosed method includes preparing a combinatorial library of materials, and identifying library members that are semiconductors. The method may include determining a thermoelectric figure of merit, ZT, for each member of a second combinatorial library of materials. The method determines ZT by applying an oscillatory voltage across the library members, measuring power dissipated by library members, and calculating ZT from the power dissipated. The method may also include isolating single-phase materials of the semiconducting library members. The present invention also discloses an apparatus for discovering thermoelectric materials using combinatorial techniques. The apparatus includes a first combinatorial library of materials comprised of thin films arrayed on a substrate, and a device for identifying semiconducting members of the first combinatorial library. In addition, the apparatus may include a device for measuring ZTnulla voltage source for applying an oscillatory electrical potential across members of a second combinatorial library arrayed on a substrate, and a device for measuring the resulting power dissipated by library members. The apparatus may also include a device for isolating single-phase materials of library members that were identified as semiconductors.

Abstract translation: 本发明公开了用于制作和筛选组合文库以识别半导体和热电材料的方法，材料和装置。 所公开的方法包括制备材料的组合文库，以及识别作为半导体的文库成员。 该方法可以包括确定材料的第二组合库的每个构件的热电特性值ZT。 该方法通过在库构件上施加振荡电压来确定ZT，测量库构件消耗的功率，以及从功率消耗计算ZT。 该方法还可以包括隔离半导体文库成员的单相材料。 本发明还公开了一种使用组合技术发现热电材料的装置。 该装置包括由衬底上排列的薄膜组成的材料的第一组合库，以及用于识别第一组合库的半导电构件的装置。 此外，该装置可以包括用于测量ZT的装置，用于在排列在衬底上的第二组合库的构件上施加振荡电位的电压源，以及用于测量由库构件消散的所得功率的装置。 该装置还可以包括用于隔离被识别为半导体的库成员的单相材料的装置。

公开(公告)号：US20030204034A1

公开(公告)日：2003-10-30

申请号：US10104740

申请日：2002-03-22

Applicant: Symyx Technologies, Inc.

Inventor： Dominique Charmot ,  Han-Ting Chang ,  Manikandan Jayaraman ,  Victor Nava-Salgado

IPC: C08F004/04

CPC classification number: C07D295/24 ,  C07C329/16 ,  C07C2601/14 ,  C07D207/46 ,  C07D209/30 ,  C07D291/06 ,  C08F2/38 ,  C08F293/005

Abstract: Control agents that have an oxygen-nitrogen bond covalently bonded to a thiocarbonyl moiety are provided for living-type free radical polymerization of a wide variety of monomers, particularly vinyl monomers.

Abstract translation: 具有共价键合到硫代羰基部分上的氧 - 氮键的对照试剂被提供用于多种单体，特别是乙烯基单体的活性型自由基聚合。

公开(公告)号：US20030172724A1

公开(公告)日：2003-09-18

申请号：US10099452

申请日：2002-03-15

Applicant: Symyx Technologies, Inc.

Inventor： Miroslav Petro ,  Son Hoai Nguyen

IPC: G01N030/00

CPC classification number: G01N30/6017 ,  G01N30/02 ,  B01D15/14

Abstract: A liquid chromatography column distributor spreads liquid over the internal cross sectional area of the column to facilitate separation of the liquid in the column into its constituent components for analysis, particularly where the volume of liquid is small and the rate of flow through the column is high. The distributor is useful for small volumes, less than 100 micro liters. The distribution is preferably done in two or more stages by two or more plates arranged in series. This arrangement keeps the flow paths short and volumes of channels in the plate carrying the liquid small. The distributor may be used in a high performance liquid chromatography (HPLC) in which liquid flows at high rates through the column. The distributor is constructed to protect the liquid sample from damage.

Abstract translation: 液相色谱柱分配器将液体扩散到柱的内部横截面积上，以便于将柱中的液体分离成其组分成分用于分析，特别是在液体体积小并且流过柱的流量高时 。 经销商对小体积，小于100微升有用。 分布优选通过串联布置的两个或更多个板在两个或更多个阶段中进行。 这种布置保持流动路径短，并且载运液体的板中的通道的体积小。 分配器可用于高效液相色谱（HPLC），其中液体以高速通过柱流动。 分配器被构造成保护液体样品免受损坏。

公开(公告)号：US20030169638A1

公开(公告)日：2003-09-11

申请号：US10408812

申请日：2003-04-08

Applicant: Symyx Technologies, Inc.

Inventor： Ralph B. Nielsen

IPC: B01F007/00

CPC classification number: B01F13/1022 ,  B01F7/00033 ,  B01F7/0015 ,  B01F7/002 ,  B01F7/18 ,  B01F13/1013 ,  B01J2219/00283 ,  B01J2219/00306 ,  B01J2219/00481 ,  B01J2219/00495 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00745 ,  B01J2219/00747 ,  C40B30/08 ,  C40B40/18 ,  C40B60/14

Abstract: Method and apparatus for mixing small volumes of reaction components. In one application, a plurality of removable vessels are placed in a parallel reactor, and reaction components are delivered to each vessel. An impeller is rotated in each vessel to mix the components. Each impeller has a rotary shaft and at least one blade on the shaft for placement in the reaction components. The blade is dimensioned so that one rotation of the impeller causes the blade to sweep out a sweep volume representing a large amount of the fill volume of the vessel.

Abstract translation: 用于混合少量反应组分的方法和装置。 在一个应用中，将多个可移除的容器放置在平行的反应器中，并将反应组分输送到每个容器。 在每个容器中旋转叶轮以混合组分。 每个叶轮具有旋转轴和轴上的至少一个叶片，用于放置在反应部件中。 叶片的尺寸被设计成使得叶轮的一个旋转使叶片扫出表示容器的大量填充体积的扫掠体积。

公开(公告)号：US20030125484A1

公开(公告)日：2003-07-03

申请号：US10315512

申请日：2002-12-09

Applicant: Symyx Technologies, Inc.

Inventor： J. Christopher Freitag ,  Damian Hajduk ,  Ralph B. Nielsen ,  Adam Safir ,  Richard Tiede

IPC: C08F002/00

CPC classification number: B01J19/0046 ,  B01J2219/0029 ,  B01J2219/00308 ,  B01J2219/0031 ,  B01J2219/00313 ,  B01J2219/00315 ,  B01J2219/00319 ,  B01J2219/00351 ,  B01J2219/00481 ,  B01J2219/00484 ,  B01J2219/00495 ,  B01J2219/00585 ,  B01J2219/00691 ,  B01J2219/0072 ,  B01J2219/00722 ,  C40B40/14 ,  C40B60/14 ,  Y10S526/92 ,  Y10T436/11 ,  Y10T436/25 ,  Y10T436/25625 ,  Y10T436/2575

Abstract: A method and apparatus for reacting a plurality of different mixtures in parallel in a semi-batch or continuous mode is provided. Each reaction is contained within a reactor vessel, the reactor vessels combined into a reactor block. Reactant(s) to be added during the reaction are kept in a header barrel, which has a plunger to feed reactant(s) from the header barrel through a transfer line into the reactor vessel. The plunger is moved using a drive system. The header barrels are optionally combined in a header block. The header block is sealed to a plate containing the transfer lines, which in turn is sealed to the reactor block. A latch mechanism is provided for easy sealing of the reactor and header blocks to the plate. The entire apparatus may be placed on a rocker or rotating plate for mixture as the reaction is proceeding.

Abstract translation: 提供了以半批或连续模式并行地进行多种不同混合物的方法和装置。 每个反应都包含在反应器容器中，反应器容器组合成反应器块。 在反应过程中加入的反应物保持在集管筒中，其具有柱塞，以通过输送管将反应物从集管筒送入反应器容器。 柱塞使用驱动系统移动。 标题桶可选地组合在标题块中。 集管块被密封到含有输送管线的板上，转移管路又与反应器块密封。 提供了一种闭锁机构，用于容易地将反应堆和集管块密封到板上。 当反应进行时，整个装置可以放置在摇臂或旋转板上用于混合。