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1665 条记录 (耗时 0.065 秒)

    Hydrogen peroxide-based skin disinfectant
    95.
    发明授权
    Hydrogen peroxide-based skin disinfectant 有权
    基于过氧化氢的皮肤消毒剂

    公开(公告)号：US09198935B2

    公开(公告)日：2015-12-01

    申请号：US13832921

    申请日：2013-03-15

    申请人： Navid Omidbakhsh ,  Pierre Grascha

    发明人： Navid Omidbakhsh ,  Pierre Grascha

    IPC分类号： A61K33/40 ,  A61K8/22 ,  A61K8/368 ,  A61K8/44 ,  A61K8/49 ,  A61K8/55 ,  A01N59/00 ,  A01N25/30 ,  A01N25/22 ,  A01N43/08 ,  A01N37/40 ,  A01N37/10 ,  A61Q17/00

    CPC分类号： A61K33/40 ,  A01N59/00 ,  A61K8/22 ,  A61K8/368 ,  A61K8/44 ,  A61K8/442 ,  A61K8/4946 ,  A61K8/4973 ,  A61K8/55 ,  A61K47/10 ,  A61K47/38 ,  A61Q17/005 ,  Y02A50/473 ,  A01N25/30 ,  A01N25/22 ,  A01N43/08 ,  A01N37/40 ,  A01N37/10 ,  A01N2300/00

    摘要： An aqueous skin disinfecting solution has a pH of from about 2 to about 6, and consists of at least (a) hydrogen peroxide in a concentration of from about 0.01 to about 4% w/w; (b) at least one surfactant chosen from alkyl betaines, alkyl amidopropyl betaines, alkyl amidopropyl betaine amides, alkylsulfobetaines, alkyl amphocarboxylates and amine oxides in a concentration of from about 0.01 to about 15% w/w; (c) at least one hydrogen peroxide stabilizer in a concentration of from about 0.01 to about 4% w/w; (d) at least one member chosen from cyclic carboxylic acids and salts thereof in a concentration of from about 0.01 to about 4% w/w; (e) at least one skin conditioning agent in a concentration of from about 0.01 to about 10% w/w; and (f) an effective amount of at least one solvent. The invention can be provided in concentrated or dried powdered form.

    摘要翻译： 水性皮肤消毒溶液的pH为约2至约6，并且由至少（a）浓度为约0.01至约4％w / w的过氧化氢组成; （b）至少一种选自烷基甜菜碱，烷基酰胺丙基甜菜碱，烷基酰胺丙基甜菜碱酰胺，烷基磺基甜菜碱，烷基二羧酸盐和胺氧化物的表面活性剂，其浓度为约0.01至约15％w / w; （c）至少一种浓度为约0.01至约4％w / w的过氧化氢稳定剂; （d）至少一种选自环状羧酸及其盐的组分，其浓度为约0.01至约4％w / w; （e）至少一种浓度为约0.01至约10％w / w的皮肤调理剂; 和（f）有效量的至少一种溶剂。 本发明可以以浓缩或干燥的粉末形式提供。

    Treating patients with intravenous ibuprofen
    98.
    发明授权
    Treating patients with intravenous ibuprofen 有权
    治疗静脉注射布洛芬的患者

    公开(公告)号：US09114068B2

    公开(公告)日：2015-08-25

    申请号：US14264267

    申请日：2014-04-29

    申请人： Cumberland Pharmaceuticals Inc.

    发明人： Leo Pavliv ,  Amy Dix Rock

    IPC分类号： A01N37/10 ,  A61K31/19 ,  A61K9/00 ,  A61K31/192 ,  A61K31/198

    CPC分类号： A61K9/0019 ,  A61K31/19 ,  A61K31/192 ,  A61K31/198

    摘要： Methods of treating a patient in need thereof, comprising administering to the critically ill patient an intravenous pharmaceutical composition comprising ibuprofen in an amount effective to treat at least one condition in the patient chosen from pain, inflammation, and fever and to provide a clinically relevant effect on mean arterial pressure of the patients during the dosage interval comprising no increase or no statistically significant increase in mean arterial pressure.

    摘要翻译： 治疗有需要的患者的方法包括向危重患者施用含有有效治疗选自疼痛，炎症和发热的患者中的至少一种状况的布洛芬的静脉内药物组合物并提供临床相关效应 在剂量间隔期间患者的平均动脉压不包括平均动脉压升高或无统计学显着性增加。

    Interferon-statin combination cancer therapy
    99.
    发明授权
    Interferon-statin combination cancer therapy 有权
    干扰素 - 他汀联合癌症治疗

    公开(公告)号：US09034310B2

    公开(公告)日：2015-05-19

    申请号：US10370434

    申请日：2003-02-20

    申请人： Stephen B. Cantrell

    发明人： Stephen B. Cantrell

    IPC分类号： A61K38/21 ,  C07K14/555 ,  C07K14/56 ,  C07K14/565 ,  A61K31/22 ,  A01N43/38 ,  A61K31/405 ,  A01N37/10 ,  A61K31/19

    CPC分类号： A61K38/212 ,  A61K38/21 ,  A61K38/215 ,  A61K38/217 ,  A61K2300/00

    摘要： A method for pharmacological treatment of cancers and other diseases is presented which includes the novel combination of a statin (Hmg-CoA reductase inhibitor, such as lovastatin, simvastatin, atorvastatin, cerivastatin, fluvastatin, pravastatin, or newer agents), with an interferon (such as interferon alfa-2b or others) and also including concurrent administration of selenium and calcium. The method disclosed in this invention is useful because it can prove more effective than previously known therapies for certain diseases and because its use may be more tolerable, less disfiguring, and less expensive than other methods. The method here disclosed can be readily reproduced by any person skilled in the art of treating disease.

    摘要翻译： 提出了一种癌症和其他疾病的药理学治疗方法，其中包括他汀类药物（Hmg-CoA还原酶抑制剂，如洛伐他汀，辛伐他汀，阿托伐他汀，西立伐他汀，氟伐他汀，普伐他汀或新药）与干扰素 例如干扰素α-2b或其他），还包括同时施用硒和钙。 本发明公开的方法是有用的，因为它可以证明比某些疾病以前已知的治疗更有效，并且因为其使用可能比其他方法更可耐受，更少的损伤，更便宜。 本文公开的方法可以容易地由本领域技术人员处理疾病复制。