公开(公告)号：US20180128947A1

公开(公告)日：2018-05-10

申请号：US15840834

申请日：2017-12-13

申请人： Trustees of Boston University

发明人： Bjoern Markus Reinhard ,  Luca Dal Negro

IPC分类号： G02B5/00 ,  B82Y30/00 ,  C03C17/40 ,  G01N21/01 ,  G01N21/65

CPC分类号： G02B5/008 ,  B82Y30/00 ,  C03C17/40 ,  C03C2217/255 ,  C03C2217/425 ,  G01N21/01 ,  G01N21/658 ,  G01N2201/02 ,  Y10T428/12104 ,  Y10T428/24909

摘要： Defined nanoparticle cluster arrays (NCAs) with dimensions up to 25.4 μm square are fabricated on a 10 nm gold film using template guided self-assembly. Structural parameters are precisely controlled, allowing systematic variation of the number of nanoparticles in the clusters (n) and edge to edge separation (∧) between 1

公开(公告)号：US20180117587A1

公开(公告)日：2018-05-03

申请号：US15729729

申请日：2017-10-11

申请人： ILLUMINA, INC. ,  ILLUMINA, SINGAPORE PTE. LTD.

发明人： Richard L. Lemoine ,  James Osmus ,  Sz-Chin Steven Lin ,  Beng Keong ANG

IPC分类号： B01L3/00 ,  G01N21/01 ,  G01N21/75

CPC分类号： B01L3/502715 ,  B01L3/50273 ,  B01L3/502738 ,  B01L2200/02 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2200/028 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/0609 ,  B01L2300/0672 ,  B01L2300/0829 ,  B01L2400/0478 ,  B01L2400/0644 ,  F04B19/006 ,  G01N21/01 ,  G01N21/75

摘要： A cartridge assembly that comprises a housing, including a flow cell chamber to receive a flow cell, and a well plate having liquid wells to receive desired amounts of liquids. The well plate includes a valve station, a pump station and a fluidics analysis station, and channels associated therewith. A pump assembly to manage fluid flow through the channels between the pump station and the fluidics analysis station. A rotary valve assembly that includes a rotor shaft and rotor valve positioned to rotate about a rotational axis and to selectively couple the wells to the pump station. The rotor shaft includes a dual spline configuration at the distal end thereof. The dual spline configuration has first and second sets of splines. The first set of splines forms a drive interface and the second set of splines forms a position encoding interface.

公开(公告)号：US20180088037A1

公开(公告)日：2018-03-29

申请号：US15711718

申请日：2017-09-21

申请人： DALIAN UNIVERSITY OF TECHNOLOGY

发明人： Jiaxu LIU ,  Qin XIN ,  Cuilan MIAO ,  Jilei WANG ,  Jie XU ,  Hong MIAO ,  Hongchen GUO

IPC分类号： G01N21/35 ,  G01N21/01

CPC分类号： G01N21/35 ,  G01J3/00 ,  G01J3/42 ,  G01N21/01 ,  G01N21/3504

摘要： A real-time double-beam in situ infrared spectrum system and a method thereof. The system comprises two identical infrared spectrometers and a double-beam infrared reactor cell, wherein the double-beam infrared reactor cell is formed by connecting a sample cell and a reference cell which are identical, the sample cell and the reference cell are at the same level and respectively correspond to a sample spectrometer and a reference spectrometer, the two infrared spectrometers are synchronously controlled by computers, to synchronously collect spectrograms of sample beams and background beams in real time, so as to obtain real information about a species on the catalyst surface changing with the reaction time, and eliminate gas molecule vibration spectrum interference in a real-time state and transmission spectrum interference generated under a heating condition. The present invention makes a characterization result become more accurate and reliable, so that real-time information about an active center of the catalyst surface, an active phase and an intermediate species at different temperatures may be obtained under a changeable gas phase component condition.

公开(公告)号：US20180088030A1

公开(公告)日：2018-03-29

申请号：US15686081

申请日：2017-08-24

申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE

发明人： Dae-Sik LEE ,  Moon Youn JUNG ,  Jae-Ki SIM

IPC分类号： G01N21/27 ,  G01N21/01

CPC分类号： G01N21/27 ,  G01N21/01 ,  G01N21/8483 ,  G01N2021/0112 ,  G01N2021/1742

摘要： Provided is an apparatus for analyzing a bio-material. According to an embodiment of the inventive concept, the apparatus may include a light distribution part having grooves, a reflective layer provided on the grooves, and a light emitting part configured to emit light to the light distribution part. The grooves may be recessed from a top surface of the light distribution part, and sidewalls of the grooves may be inclined with respect to the top surface of the light distribution part. The grooves may include a first groove and a second groove. A distance between the light emitting part and the second groove may be greater than that between the light emitting part and the first groove, and a bottom surface of the second groove may be disposed at a level lower than that of a bottom surface of the first groove.

公开(公告)号：US20180079996A1

公开(公告)日：2018-03-22

申请号：US15568093

申请日：2016-03-28

申请人： Hitachi High-Technologies Corporation

发明人： Hideaki MINEKAWA ,  Muneo MAESHIMA ,  Akira MASUYA

IPC分类号： C12M1/38 ,  C12M1/34 ,  G01N21/01

摘要： This sensitivity measuring device is provided with: a stage for placing a sample container; a temperature adjustment device that is provided with an upper heating body and a lower heating body, which are disposed above and below the sample container; and an image pickup device for picking up an image of the sample container, said image pickup device being provided with a lighting apparatus and an image pickup apparatus. Each of the upper heating body and the lower heating body has a structure wherein the temperature of a first region, a peripheral portion, is higher than the temperature of a second region including a center portion.

公开(公告)号：US20180073976A1

公开(公告)日：2018-03-15

申请号：US15813444

申请日：2017-11-15

申请人： OLYMPUS CORPORATION

发明人： Kentaro IMOTO

IPC分类号： G01N21/01 ,  G01N21/64 ,  G02B21/00

CPC分类号： G01N21/01 ,  G01N21/64 ,  G01N21/6458 ,  G01N2201/06113 ,  G01N2201/10 ,  G02B21/0032 ,  G02B21/0048 ,  G02B21/0076 ,  G02B21/0084

摘要： Provided is an image-obtaining device including: an illumination-light generating unit that modulates an intensity of light emitted from a light source, and generates illumination light beams having mutually linearly independent patterns and including modulated illumination light and unmodulated illumination light; an illumination optical system that irradiates different positions on a sample with the illumination light beams generated; a light-detecting unit that detects combined signal light resulting from combining signal light beams generated at irradiation positions irradiated with the illumination light beams, and outputs a combined signal; and a demodulation unit that separates, from the combined signal output, a modulated local signal by using a time integral of a product of a demodulation signal corresponding to the modulated illumination light beam and the combined signal, and separates an unmodulated local signal by subtracting a sum of the modulated local signals from a time integral of the combined signal.

公开(公告)号：US09914513B2

公开(公告)日：2018-03-13

申请号：US14535417

申请日：2014-11-07

申请人： ABB SCHWEIZ AG

发明人： Gregory F. Rossano ,  William Eakins ,  Daniel T. Lasko ,  Thomas A. Fuhlbrigge ,  Andrew M. Salm ,  George Zhang

IPC分类号： B63G8/00 ,  G21C17/013 ,  B63G8/04 ,  G01D11/24 ,  G01N21/88 ,  G01R31/02 ,  G01M3/38 ,  E21B23/00 ,  B63G8/08 ,  G01N21/01 ,  B63G8/22 ,  H01F27/12

CPC分类号： B63G8/001 ,  B63G8/04 ,  B63G8/08 ,  B63G8/22 ,  B63G2008/002 ,  E21B2023/008 ,  G01D11/24 ,  G01M3/38 ,  G01N21/88 ,  G01N2021/0112 ,  G01R31/027 ,  G21C17/013 ,  H01F27/12

摘要： An inspection device for use in a fluid container includes at least one thrust device, at least one ballast device and a cage which carries the at least one thrust device and the at least one ballast device. The cage includes at least two bars. Each bar provides an opening, the openings forming a cage cavity to carry the at least one thrust device and the at least one ballast device.

公开(公告)号：US09909171B2

公开(公告)日：2018-03-06

申请号：US14857379

申请日：2015-09-17

申请人： Takara Bio USA, Inc.

发明人： Victor Joseph ,  Amjad Huda ,  Alnoor Shivji ,  Jie Zhou

IPC分类号： C12Q1/68 ,  B01L3/00 ,  B01L7/00 ,  B82Y30/00 ,  G01N21/03 ,  G01N35/00 ,  G01N21/01 ,  H01L27/144 ,  H01L31/0203 ,  H01L31/0232 ,  H01L31/024 ,  H01L31/105 ,  H01L31/18 ,  G01N21/64 ,  G01N21/76 ,  G01N35/04

CPC分类号： C12Q1/686 ,  B01L3/50851 ,  B01L3/50853 ,  B01L7/52 ,  B01L7/54 ,  B01L2200/0689 ,  B01L2300/044 ,  B01L2300/0636 ,  B01L2300/0654 ,  B01L2300/0819 ,  B01L2300/0829 ,  B01L2300/18 ,  B01L2300/1822 ,  B01L2300/1827 ,  B82Y30/00 ,  C12Q1/6806 ,  C12Q1/6844 ,  G01N21/01 ,  G01N21/0332 ,  G01N21/6408 ,  G01N21/6452 ,  G01N21/76 ,  G01N35/0099 ,  G01N2021/6417 ,  G01N2021/6484 ,  G01N2035/0405 ,  G01N2201/0231 ,  H01L27/1443 ,  H01L31/0203 ,  H01L31/02325 ,  H01L31/024 ,  H01L31/105 ,  H01L31/18 ,  C12Q2565/501

摘要： The present invention provides miniaturized instruments for conducting chemical reactions where control of the reaction temperature is desired or required. Specifically, this invention provides chips and optical systems for performing and monitoring temperature-dependent chemical reactions. The apparatus and methods embodied in the present invention are particularly useful for high-throughput and low-cost amplification of nucleic acids.

公开(公告)号：US09903813B2

公开(公告)日：2018-02-27

申请号：US14734687

申请日：2015-06-09

申请人： KLA-TENCOR CORPORATION

发明人： Nuriel Amir

IPC分类号： G01N21/00 ,  B05D5/00 ,  G01N21/47 ,  B05D1/32 ,  G01N21/01 ,  G03F7/20

CPC分类号： G01N21/4785 ,  B05D1/32 ,  G01N21/01 ,  G03F7/70466 ,  G03F7/70633 ,  G03F7/70683

摘要： Multiply patterned metrology targets and target design methods are provided to enable pitch walk measurements using overlay measurements. Multiply patterned structures having single features or spacers produced simultaneously and sharing a common pitch with the paired features or spacers are used to express pitch walk as a measurable overlay between the structures. For example, targets are provided which comprise a first multiply patterned structure having a single left-hand feature or spacer produced simultaneously and sharing a common pitch with the respective paired features or spacers, and a second multiply patterned structure having a single right-hand feature or spacer produced simultaneously and sharing a common pitch with the respective paired features or spacers.

公开(公告)号：US20180052315A1

公开(公告)日：2018-02-22

申请号：US15557848

申请日：2016-04-01

申请人： MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.

发明人： Jan Huisken ,  Gopi Shah

IPC分类号： G02B21/36 ,  G02B21/32 ,  F16C32/04 ,  G01N21/01

CPC分类号： G02B21/367 ,  F16C32/0406 ,  G01N21/01 ,  G02B21/32

摘要： Method for imaging regions of a sample using a light source and an optical detection means and at least one device for moving the sample in three dimensions, comprising the following method steps: a) introducing at least one magnetic element into the sample, b) applying a magnetic field by means of the at least one device for moving the sample in three dimensions, the magnetic field interacting with the at least one magnetic element introduced into the sample, c) arranging the region of the sample in a radiation region of the light source and in a detection region of the detection means, d) emitting first light beams from the light source onto the sample, e) generating second light beams by means of the sample, f) recording an image of a region of the sample by capturing a proportion, incident on the detection means from the sample, of the second light beams, g) moving the at least one magnetic element and the sample containing this at least one magnetic element by varying the magnetic field, h) repeating steps d) to g) until a predeterminable number of images have been recorded.