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137 条记录 (耗时 0.035 秒)

    PHYTONUTRIENT COMPOSITIONS FROM MUSHROOMS OR FILAMENTOUS FUNGI AND METHODS OF USE
    15.
    发明申请
    PHYTONUTRIENT COMPOSITIONS FROM MUSHROOMS OR FILAMENTOUS FUNGI AND METHODS OF USE 审中-公开
    来自真菌或真菌的物理组合物及其使用方法

    公开(公告)号：US20070244175A1

    公开(公告)日：2007-10-18

    申请号：US11686033

    申请日：2007-03-14

    申请人： Robert Beelman ,  N. Dubost ,  Devin Peterson ,  Marvin Hausman

    发明人： Robert Beelman ,  N. Dubost ,  Devin Peterson ,  Marvin Hausman

    IPC分类号： A61K31/4166 ,  A01G1/04 ,  C07D233/28

    CPC分类号： C07D233/02 ,  C07D233/66

    摘要： This invention is directed to treating disease states or conditions associated with the treatment and prevention of neurodegeneration and neurodegenerative disease states, and treatment of radiation damage. The invention relates to novel phytonutrient compositions and compounds comprising L-ergothioneine and/or selenium. The invention also provides a method of administering these compositions and combinations to humans or animals in need thereof.

    摘要翻译： 本发明涉及治疗与治疗和预防神经变性和神经变性疾病状态相关的疾病状态或病症，以及治疗辐射损伤。 本发明涉及新型植物营养素组合物和包含L-麦角硫素和/或硒的化合物。 本发明还提供了将这些组合物和组合施用于有需要的人或动物的方法。

    Multi-substituted imidazolines and method of use thereof
    16.
    发明申请
    Multi-substituted imidazolines and method of use thereof 有权

    公开(公告)号：US20050192330A1

    公开(公告)日：2005-09-01

    申请号：US11099885

    申请日：2005-04-06

    申请人： Jetze Tepe ,  Satyamaheshwar Peddibhotla

    发明人： Jetze Tepe ,  Satyamaheshwar Peddibhotla

    IPC分类号： C07D233/22 ,  C07D233/28 ,  C07D401/04 ,  C07D403/06 ,  A61K31/4178 ,  C07D233/04 ,  C07D43/02

    CPC分类号： C07D401/04 ,  C07D233/22 ,  C07D233/28 ,  C07D403/06

    摘要： A new class of imidazolines as 4-position acids or esters with very potent anti-inflammatory as well as antimicrobial activity is described. The synthesis of these imidazolines includes a multicomponent reaction applicable to a combinatorial synthetic approach. The combination of these two key characteristics provides an effective therapeutic drug in the treatment of septic shock as well as many other inflammatory (arthritis and asthma) and infectious disorders. The use of this novel class of non-steroidal agents as anti-inflammatory agents (for the treatment of asthma etc.), antibacterial agents and antiseptic agents is described. The compounds are also useful in the treatment of tumors (such as cancers). The imidazolines are potent inhibitors of the transcription factor NF-κB as well as potent activity against the Gram (+) bacterium B. subtillus and B. cereus with MIC values in the range of 50 μm/mL.