ENHANCED SURFACE PLASMON RESONANCE METHOD
    22.
    发明申请
    ENHANCED SURFACE PLASMON RESONANCE METHOD 有权
    增强表面等离子体共振方法

    公开(公告)号:US20150109614A1

    公开(公告)日:2015-04-23

    申请号:US14382334

    申请日:2013-03-05

    Applicant: BIOSURFIT S.A.

    Abstract: The disclosure relates to processing SPR signals, in particular signals obtained by illuminating a conductive surface with light at two wavelengths. Processing SPR signals can involve processing a first and second signal indicative of an intensity of light, received from a conductive layer at which SPR has occurred, as a function of angle of incidence, reflection or diffraction at the layer. The first and second signals each have two dips corresponding to a respective wavelength of the light at a respective angle at which surface plasmon resonance occurs for the respective wavelength and a peak between the two dips. The processing includes deriving a first and second value of a quantity indicative of signal magnitudes in the region of the peak. The first and second values can be compared to detect a change in refractive index at the layer after the first signal and before the second signal was captured.

    Abstract translation: 本公开涉及处理SPR信号,特别是通过用两个波长的光照射导电表面而获得的信号。 处理SPR信号可以涉及处理表示从已经发生SPR的导电层接收的光的强度的第一和第二信号作为该层处的入射角,反射或衍射的函数。 第一和第二信号各自具有对应于在相应波长的相应波长处的两个倾斜,在该角度处,针对相应波长发生表面等离子体共振并且在两个下降之间产生峰值。 该处理包括导出指示峰值区域中的信号幅度的量的第一值和第二值。 可以比较第一和第二值以检测第一信号之后的层和第二信号被捕获之前的折射率的变化。

    Gas sensors and methods of controlling light sources therefor
    24.
    发明授权
    Gas sensors and methods of controlling light sources therefor 有权
    气体传感器和控制光源的方法

    公开(公告)号:US07835004B2

    公开(公告)日:2010-11-16

    申请号:US11899508

    申请日:2007-09-06

    Abstract: A gas sensor includes a light source, a power source in operative connection with the light source and a control system in operative connection with the light source and the power supply. The control system is adapted to control power input from the power source to the light source such that the time period of the control frequency is shorter than the thermal time constant of at least one of (i) the infrared light source, (ii) the gas within the sensor, or (iii) a detector of the sensor. The time period of the control frequency can, for example, be no greater than ⅓ of the thermal time constant, no greater than 1/10 of the thermal time constant, or even no greater than 1/20 of the thermal time constant. A feedback signal can be provided to the control system assist in achieving control.

    Abstract translation: 气体传感器包括光源,与光源可操作地连接的电源和与光源和电源可操作地连接的控制系统。 控制系统适于控制从电源到光源的输入功率,使得控制频率的时间周期短于(i)红外光源,(ii) 传感器内的气体,或(iii)传感器的检测器。 控制频率的时间段可以例如不大于热时间常数的1/3,不大于热时间常数的1/10,或甚至不大于热时间常数的1/20。 可以向控制系统提供反馈信号以帮助实现控制。

    Self-referencing instrument and method thereof for measuring electromagnetic properties
    25.
    发明授权
    Self-referencing instrument and method thereof for measuring electromagnetic properties 有权
    用于测量电磁特性的自参考仪器及其方法

    公开(公告)号:US07321424B2

    公开(公告)日:2008-01-22

    申请号:US11197195

    申请日:2005-08-04

    Abstract: In a self-referencing instrument for measuring electromagnetic radiation, a mounting member to which a sample can be coupled moves the sample such that, in a first position, the electromagnetic radiation impinges on the sample, and, in a second position, the electromagnetic radiation does not impinge on the sample. A detection unit receives the electromagnetic radiation from the sample and generates a sample signal when the sample is in the first position, and the detection unit receives the electromagnetic radiation from the source and generates a reference signal when the sample is in the second position. A processor coupled to the detection unit processes the reference signal and the sample signal. This results in a continuous, accurate reference measurement, and permits the instrument to efficiently compensate for error, while offering accurate measurements.

    Abstract translation: 在用于测量电磁辐射的自参考仪器中,可以耦合样品的安装构件移动样品,使得在第一位置,电磁辐射照射在样品上,并且在第二位置中,电磁辐射 不会影响样品。 检测单元从样本接收电磁辐射,并且当样本处于第一位置时产生采样信号,并且当样本处于第二位置时,检测单元从源接收电磁辐射并产生参考信号。 耦合到检测单元的处理器处理参考信号和采样信号。 这将产生连续,准确的参考测量,并允许仪器有效地补偿误差,同时提供准确的测量。

    Multi-channel, self-calibrating fiber-coupled raman spectrometers including diagnostic and safety features
    26.
    发明授权
    Multi-channel, self-calibrating fiber-coupled raman spectrometers including diagnostic and safety features 有权
    多通道自校准光纤耦合拉曼光谱仪,包括诊断和安全功能

    公开(公告)号:US07158225B2

    公开(公告)日:2007-01-02

    申请号:US10764319

    申请日:2004-01-23

    Abstract: A multi-channel, reconfigurable fiber-coupled Raman instrument uses fiber optic switches for laser and calibration light routing to facilitate automated calibration, diagnosis and operational safety. The system allows wavelength axis calibration on all channels; laser wavelength calibration (including multiple and/or backup laser options); fiber coupling optimization; fault detection/diagnosis; and CCD camera binning setup. In the preferred embodiment, dedicated calibration channels surround data channels on a 2-dimensional CCD dispersed slit image implemented using a unique cabling architecture. This “over/under” calibration interpolation approach facilitates quasi-simultaneous or sequential calibration/data acquisitions. CCD binning between sequential calibration and data acquisitions enables higher density multi-channel operation with tilted images based upon a multiplexed grating configuration. A diamond sample is used as a Raman shift reference for laser calibration, preferably in the form of a small disc sampled with an edge-illuminating probe using two unfiltered fibers.

    Abstract translation: 多通道可重构光纤耦合拉曼仪器使用光纤开关进行激光和校准光路由,便于自动校准,诊断和操作安全。 该系统允许所有通道上的波长轴校准; 激光波长校准(包括多个和/或备用激光选项); 光纤耦合优化; 故障检测/诊断; 和CCD相机合并设置。 在优选实施例中,专用校准通道围绕使用独特布线架构实现的二维CCD分散狭缝图像上的数据通道。 这种“过/欠”校准插值方法有助于准同步或连续校准/数据采集。 顺序校准和数据采集之间的CCD合并使得基于多路复用光栅配置的倾斜图像能够实现更高密度的多通道操作。 金刚石样品用作用于激光校准的拉曼移位参考,优选地以使用两个未滤光纤维的边缘照明探针采样的小盘的形式。

    Method of and apparatus for inspecting paint coating
    28.
    发明授权
    Method of and apparatus for inspecting paint coating 失效
    检查涂料的方法和设备

    公开(公告)号:US5066132A

    公开(公告)日:1991-11-19

    申请号:US564167

    申请日:1990-08-08

    Abstract: An apparatus for inspecting a coating formed on a workpiece, comprising a light emitter and a light receiver positioned on respective sides of the workpiece; an amplifier for amplifying a detection signal from the light receiver and for generating an amplified output signal; a comparator for comparing the amplified output signal with a predetermined level thereby to generate a control signal indicative of a difference between the amplified output signal and the predetermined level; a zero adjustment for adjusting the amplified output signal to a zero value; and a tuning circuit for tuning the amplified output signal, which is generated from the amplifier when the workpiece to be inspected has not yet been formed with the coating, to a predetermined tuned value. The tuning circuit is operable to vary the amplification factor of the amplifier and also to the intensity of light emitted by the light emitter. In place of the tuning circuit, an amplification factor setting citcuit may be used for sampling the light transmissivity of the workpiece and for selecting one of amplification factors according to the result of sampling. After the formation of the coating on the workpiece, the amplified output signal may decrease with a decrease of the light transmissivity of the workpiece, and the coating condition is determined depending on whether or not the amplified output signal is lower than the predetermined level.

    Abstract translation: 一种用于检查在工件上形成的涂层的装置,包括位于工件的相应侧面上的光发射器和光接收器; 放大器,用于放大来自光接收器的检测信号并产生放大的输出信号; 比较器,用于将放大的输出信号与预定电平进行比较,从而产生指示放大的输出信号与预定电平之间的差的控制信号; 用于将放大的输出信号调整为零值的零调整; 以及调谐电路,用于当待检查的工件尚未形成涂层时,将放大器产生的放大的输出信号调谐到预定的调谐值。 调谐电路可操作以改变放大器的放大系数以及光发射器发射的光的强度。 代替调谐电路,可以使用放大因子设置电路来对工件的光透射率进行采样,并根据采样结果选择一个放大因子。 在工件上形成涂层之后,放大的输出信号可能随着工件的光透射率的降低而减小,并且根据放大的输出信号是否低于预定电平来确定涂覆条件。

    New and improved method and apparatus for automatic baseline and standard calibration of automatic, multichannel sequentially operable fluid sample supply, treatment and analysis means
    29.
    发明授权
    New and improved method and apparatus for automatic baseline and standard calibration of automatic, multichannel sequentially operable fluid sample supply, treatment and analysis means 失效
    自动基线自动,多通道顺序可操作流体样品供应,处理和分析方法的新改进方法和装置

    公开(公告)号:US3634868A

    公开(公告)日:1972-01-11

    申请号:US3634868D

    申请日:1970-03-13

    CPC classification number: G01N21/274 G01N35/08 G01N2201/12723

    Abstract: New and improved method and apparatus for automatic, periodic baseline and standard calibration of analysis results recording means which record the results of sample analyses performed by multichannel sample analysis means in accordance with the output of the latter are provided to compensate for drift in said analysis means output, and comprise the conditioning of said sample analysis means and the adjustment of said output to a desired value for baseline calibration for each of said channels, the conditioning of said sample analysis means and the adjustment of said output to a desired value for standard calibration for each of said channels, the comparison of said output with said desired value thereof for baseline calibration for each of said channels and, if drift has occurred, the generation of information to drive said output to said desired value for baseline calibration, the comparison of said output with said desired value thereof for standard calibration for each of said channels and, if drift has occurred, the generation of information to drive said output to said desired value thereof for standard calibration, the storing of said baseline and standard calibration information for each of said channels for repeated reuse in sequence with channel changes during sample analysis operation of said sample analysis means, and the updating of said standard and baseline calibration information for each of said channels by the standard and baseline calibration information generated during subsequent operation of said calibration apparatus.

    Abstract translation: 提供新的和改进的用于分析结果的自动,周期性基线和标准校准的方法和装置,记录装置,其记录根据后者的输出的多通道样本分析装置进行的样本分析结果,以补偿所述分析装置中的漂移 输出,并且包括对所述样本分析装置的调节和将所述输出调节到用于每个所述通道的基线校准的期望值,所述样本分析装置的调节和所述输出的调节为用于标准校准的期望值 对于每个所述通道,将所述输出与所述期望值的比较用于每个所述通道的基线校准,并且如果发生漂移,则产生用于将所述输出驱动到所述基准校准所需值的信息, 所述输出具有所述期望值,用于每个所述cha的标准校准 并且如果发生漂移,则产生用于将所述输出驱动到所述期望值的信息以用于标准校准,存储所述基准线和每个所述信道的标准校准信息,以便在样本分析期间按顺序重新使用信道变化 所述样本分析装置的操作,以及通过在所述校准装置的后续操作期间产生的标准和基线校准信息来更新每个所述通道的所述标准和基线校准信息。

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