摘要:
The present invention relates to a novel, small-scale, electrophoretic separation system based on photodefined polymers and electrode-defined sample injection. Diffusion and displacement coefficients may be modified by varying the gel concentration, the intensity of the incident UV radiation and the temperature at which the gel is run. The device is an major advance over current technology since it provides for a significant reduction in size of the micro-electrophoresis apparatus and a significant cost savings.
摘要:
An acoustical fluid control mechanism and a method of controlling fluid flow of a working fluid with the acoustical fluid control mechanism are provided. The mechanism comprises a resonance chamber that defines a cavity. The resonance chamber has a port. The cavity is sealed from the ambient but for the port for enabling oscillatory flow of a working fluid into and out of the cavity upon exposure of the resonance chamber to an acoustic signal containing a tone at a frequency that is substantially similar to a particular resonance frequency of the resonance chamber. The mechanism further includes a rectifier for introducing directional bias to the oscillatory flow of the working fluid through the port. The rectifier has an inlet connected to the port and an outlet for transmitting the directional flow of the working fluid away from the cavity. The outlet is in fluid communication with the port of the resonance chamber at least during transmission of the directional flow of the working fluid therethrough.
摘要:
An acoustical fluid control mechanism and a method of controlling fluid flow of a working fluid with the acoustical fluid control mechanism are provided. The mechanism comprises a resonance chamber that defines a cavity. The resonance chamber has a port. The cavity is sealed from the ambient but for the port for enabling oscillatory flow of a working fluid into and out of the cavity upon exposure of the resonance chamber to an acoustic signal containing a tone at a frequency that is substantially similar to a particular resonance frequency of the resonance chamber. The mechanism further includes a rectifier for introducing directional bias to the oscillatory flow of the working fluid through the port. The rectifier has an inlet connected to the port and an outlet for transmitting the directional flow of the working fluid away from the cavity. The outlet is in fluid communication with the port of the resonance chamber at least during transmission of the directional flow of the working fluid therethrough.
摘要:
The present invention relates to microfabrication and utilization of microscale electrophoresis devices as well as the separation and detection of biomolecules in microscale electrophoresis devices. The device of the present invention utilizes novel fabrication and detection methods.
摘要:
The movement and mixing of microdroplets through microchannels is described employing microscale devices, comprising microdroplet transport channels, reaction regions, electrophoresis modules, and radiation detectors. The discrete droplets are differentially heated and propelled through etched channels. Electronic components are fabricated on the same substrate material, allowing sensors and controlling circuitry to be incorporated in the same device.
摘要:
A test apparatus (400) comprising a single handler (404) is coupled to a first tester (436) and second tester (408), wherein the first (436) and second (408) testers are coupled together. A first test procedure is performed on a set of second IC's using the first tester (436), simultaneously while a second test procedure is performed on a first set of IC's using the second tester (408). Sets of IC's may be tested in parallel by a plurality of testers (436/408) within a single handler (404). The first (436) and second (408) testers may be coupled to a multiplexer (460) to allow the use of a single test head (478), which avoids having to make contact to the integrated circuit more than once, which is particularly advantageous in wafer probe testing.
摘要:
An apparatus measures a repetitive signal, including a signal generating circuit to output the repetitive signal in accordance with first clock signals which are generated by a first clock circuit. A sampling circuit samples the repetitive signal in accordance with strobe signals to output sampled signals, the strobe signals are output by a strobe generator circuit. An output circuit stores the sampled signals and outputs a reconstructed signal based on said sampled repetitive signal.
摘要:
The present invention includes a method of eliminating interference from an undersettled electrical signal, the undersettled electrical signal including a test signal at a known frequency. One embodiment of the present invention includes a method comprising the steps of providing a digitized version of the undersettled electrical signal (at 46); generating a frequency spectrum of the digitized version of the undersettled electrical signal (at 56); spectrally interpolating the frequency spectrum to generate an interference signal frequency spectrum (at 65); and subtracting the interference signal frequency spectrum (at 65) from the undersettled signal frequency spectrum (at 56) generating a settled signal spectrum (at 75). Another embodiment of the present invention includes a system comprising means (40 or 45) responsive to the undersettled electrical signal for producing a digitized version of the undersettled electrical signal (at 46); means (50) responsive to the digitized version of the undersettled signal for transforming the digitized version of the undersettled signal into a transformed signal; and means (60 and 70) including a spectral interpolator (60) responsive to the transformed signal for removing interference from the transformed signal generating a settled signal output (at 75).
摘要:
Disclosed is a method of conducting affinity chromatographic separations of biomaterials which comprises contacting the biomaterial with a solid support comprising a generally spherical bead having a generally central magnetic core and a surrounding exterior coat about the core comprising a material capable of binding with the biomaterial.
摘要:
The movement and mixing of microdroplets through microchannels is described employing silicon-based microscale devices, comprising microdroplet transport channels, reaction regions, electrophoresis modules, and radiation detectors. The discrete droplets are differentially heated and propelled through etched channels. Electronic components are fabricated on the same substrate material, allowing sensors and controlling circuitry to be incorporated in the same device.