-
公开(公告)号：US06701774B2
公开(公告)日：2004-03-09
申请号：US09801430
申请日：2001-03-07
申请人： Ravi Srinivasan , Daniel Meron Pinkas , Shenheng Guan , Michael Myslovaty , Michael Spitkovsky , James R. Engstrom , H. Sam Bergh
发明人： Ravi Srinivasan , Daniel Meron Pinkas , Shenheng Guan , Michael Myslovaty , Michael Spitkovsky , James R. Engstrom , H. Sam Bergh
IPC分类号： G01N3004
CPC分类号： G01N30/18 , B01J19/0046 , B01J2219/00286 , B01J2219/00306 , B01J2219/00704 , G01N30/466 , G01N30/6004 , G01N30/6095 , G01N30/66 , G01N30/8631 , G01N2030/185 , G01N2030/208 , G01N2030/3084 , G01N2030/8881
摘要： Gas chromatographs of the invention generally comprise four or more analysis channels. Specifically, four or more gas chromatography columns are configured for parallel analysis of four or more gaseous samples with detection being effected using a microdetector array comprising four or more microdetectors. In one embodiment, the four or more microdetectors 510 are microfabricated detectors, and are integrally formed with a substrate or with one or more microchip bodies mounted on a substrate. In a preferred embodiment, a microdetector array comprises four or more thermal conductivity detectors having one or more thin-film detection filaments. A preferred heated environment for highly parallel gas chromatographs is also disclosed.
-
公开(公告)号：US07281408B2
公开(公告)日：2007-10-16
申请号：US10718196
申请日：2003-11-20
申请人： Ravi Srinivasan , Daniel M. Pinkas , Shenheng Guan , Michael Myslovaty , Mikhail Spitkovsy , James R. Engstrom , H. Sam Bergh
发明人： Ravi Srinivasan , Daniel M. Pinkas , Shenheng Guan , Michael Myslovaty , Mikhail Spitkovsy , James R. Engstrom , H. Sam Bergh
IPC分类号： G01N30/04
CPC分类号： G01N30/18 , B01J19/0046 , B01J2219/00286 , B01J2219/00306 , B01J2219/00704 , G01N30/466 , G01N30/6004 , G01N30/6095 , G01N30/66 , G01N30/8631 , G01N2030/185 , G01N2030/208 , G01N2030/3084 , G01N2030/8881
摘要： Gas chromatographs of the invention generally comprise four or more analysis channels. Specifically, four or more gas chromatography columns are configured for parallel analysis of four or more gaseous samples with detection being effected using a microdetector array comprising four or more microdetectors. In one embodiment, the four or more microdetectors 510 are microfabricated detectors, and are integrally formed with a substrate or with one or more microchip bodies mounted on a substrate. In a preferred embodiment, a microdetector array comprises four or more thermal conductivity detectors having one or more thin-film detection filaments. A preferred heated environment for highly parallel gas chromatographs is also disclosed.
摘要翻译： 本发明的气相色谱通常包含四个或更多个分析通道。 具体地说，四个或更多个气相色谱柱被配置用于并行分析四种或更多种气态样品，其中使用包含四个或更多微量检测器的微量检测器阵列进行检测。 在一个实施例中，四个或更多个微检测器510是微制造的检测器，并且与基板或与安装在基板上的一个或多个微芯片体整体形成。 在优选实施例中，微检测器阵列包括具有一个或多个薄膜检测丝的四个或更多个热导检测器。 还公开了用于高度平行的气相色谱仪的优选的加热环境。
-
公开(公告)号：US07122156B2
公开(公告)日：2006-10-17
申请号：US09801389
申请日：2001-03-08
IPC分类号： B01L3/00
CPC分类号： B01L7/525 , B01J4/00 , B01J19/004 , B01J19/0046 , B01J19/0093 , B01J2219/00038 , B01J2219/00306 , B01J2219/00317 , B01J2219/00319 , B01J2219/00351 , B01J2219/00389 , B01J2219/00452 , B01J2219/00479 , B01J2219/00585 , B01J2219/0068 , B01J2219/00698 , B01J2219/00702 , B01J2219/0072 , B01J2219/00745 , B01J2219/00747 , B01J2219/00783 , B01J2219/00891 , B01J2219/00952 , B01L3/5025 , B01L3/5027 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/502746 , B01L7/54 , B01L2200/143 , B01L2300/0883 , B01L2400/06 , C40B30/08 , C40B40/18 , C40B60/14 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
摘要： Parallel flow reaction systems comprising four or more reaction channels are disclosed. Distribution systems, and parallel flow reaction systems comprising such distribution systems are also disclosed. Specifically, the distribution systems comprise a feed-composition subsystem for providing a different feed composition to each of the four or more reactors. In preferred embodiments, the feed composition subsystem comprises at least one set of four or more feed-component flow restrictors, each of the four or more feed-component flow restrictors having a flow resistance that varies relative to other flow restrictors in the set.
-
公开(公告)号：US07150994B2
公开(公告)日：2006-12-19
申请号：US09801390
申请日：2001-03-07
CPC分类号： B01L7/54 , B01J4/00 , B01J19/004 , B01J19/0046 , B01J19/0093 , B01J2219/00038 , B01J2219/00306 , B01J2219/00317 , B01J2219/00319 , B01J2219/00351 , B01J2219/00389 , B01J2219/00452 , B01J2219/00479 , B01J2219/00585 , B01J2219/0068 , B01J2219/00698 , B01J2219/00702 , B01J2219/0072 , B01J2219/00745 , B01J2219/00747 , B01J2219/00783 , B01J2219/0086 , B01J2219/00869 , B01J2219/00889 , B01J2219/00891 , B01J2219/0095 , B01J2219/00952 , B01L3/5025 , B01L3/5027 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/502746 , B01L7/525 , B01L2200/143 , B01L2400/06 , C40B30/08 , C40B40/18 , C40B60/14 , Y10T436/11 , Y10T436/117497 , Y10T436/25875
摘要： Parallel flow reaction systems comprising four or more reaction channels are disclosed. Distribution systems, and parallel flow reaction systems comprising such distribution systems are also disclosed. Specifically, the distribution systems comprise one or more subsystems, including for example, a flow-partitioning subsystem for providing a different flow rate to each of the four or more reactors, a pressure-partitioning subsystem for providing a different reaction pressure in the reaction cavity of each of the four or more reactors, and a feed-composition subsystem for providing a different feed composition to each of the four or more reactors. In preferred embodiments, the one or more subsystems can comprise at least one set of four or more flow restrictors, each of the four or more flow restrictors having a flow resistance that varies relative to other flow restrictors in the set.
摘要翻译： 公开了包括四个或更多个反应通道的平行流动反应系统。 还公开了分布系统和包括这种分配系统的平行流反应系统。 具体地，分配系统包括一个或多个子系统，包括例如用于向四个或更多个反应器中的每一个提供不同流量的流量分配子系统，用于在反应腔中提供不同反应压力的压力分配子系统 的四个或更多个反应器中的每一个，以及用于向四个或更多个反应器中的每一个提供不同的进料组合物的进料组成子系统。 在优选实施例中，一个或多个子系统可以包括至少一组四个或更多个流量限制器，四个或更多个限流器中的每一个具有相对于该组中的其它流量限制器而变化的流动阻力。
-
公开(公告)号：US07118917B2
公开(公告)日：2006-10-10
申请号：US10094257
申请日：2002-03-07
申请人： H. Sam Bergh , Shenheng Guan , James R. Engstrom , Steffen Hardt , Astrid Lohf , Frank Michel
发明人： H. Sam Bergh , Shenheng Guan , James R. Engstrom , Steffen Hardt , Astrid Lohf , Frank Michel
CPC分类号： B01L7/54 , B01J19/0046 , B01J19/0093 , B01J2219/00286 , B01J2219/00308 , B01J2219/00495 , B01J2219/00587 , B01J2219/00689 , B01J2219/00698 , B01J2219/00707 , B01J2219/0072 , B01J2219/00745 , B01J2219/00747 , B01J2219/00788 , B01J2219/0081 , B01J2219/00835 , B01J2219/0086 , B01J2219/00869 , B01J2219/00873 , B01J2219/0095 , B01J2219/00961 , B01L3/5027 , B01L7/00 , B01L2300/0861 , B01L2300/18 , B01L2300/1883 , C40B30/08 , C40B40/18 , C40B60/14 , Y10T436/2575
摘要： Parallel flow chemical processing systems, such as parallel flow chemical reaction systems are disclosed. These systems are adapted to simultaneously and independently vary temperature between separate flow channels, preferably by employing separate, individual heating elements in thermal communication with each of four or more parallel flow reactors. The flow reactors are preferably isolated from each other using a thermal isolation system comprising fluid-based heat exchange. In preferred embodiments, the axial heat flux can be fixedly or controllably varied.
-
6.发明授权公开(公告)号：US06737026B1
公开(公告)日：2004-05-18
申请号：US09728209
申请日：2000-11-28
申请人： H. Sam Bergh , Shenheng Guan
发明人： H. Sam Bergh , Shenheng Guan
IPC分类号： B01J1900
CPC分类号： B01L3/502715 , B01F5/0601 , B01F15/0264 , B01J19/0046 , B01J19/0093 , B01J2219/00286 , B01J2219/00306 , B01J2219/00308 , B01J2219/00313 , B01J2219/00317 , B01J2219/00337 , B01J2219/00351 , B01J2219/00353 , B01J2219/00389 , B01J2219/00418 , B01J2219/00452 , B01J2219/00479 , B01J2219/00495 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00635 , B01J2219/00637 , B01J2219/00641 , B01J2219/00657 , B01J2219/00659 , B01J2219/00704 , B01J2219/00707 , B01J2219/0072 , B01J2219/00745 , B01J2219/00747 , B01J2219/00759 , B01L3/5025 , B01L3/5027 , B01L3/502707 , B01L7/54 , B01L2200/0689 , B01L2200/146 , B01L2300/0864 , B01L2300/0874 , B01L2300/0887 , B01L2300/14 , B01L2300/18 , B01L2400/0487 , C01B3/40 , C07C17/23 , C07C45/34 , C07C45/35 , C07C45/38 , C07C45/46 , C07C45/54 , C07C45/72 , C40B30/08 , C40B40/18 , G01N30/90 , G01N31/10 , G01N35/028 , G01N2035/00158 , Y10T137/87885 , Y10T436/117497 , Y10T436/118339 , Y10T436/2575 , C07C47/06 , C07C47/22 , C07C47/04 , C07C47/127 , C07C49/403 , G01N30/466
摘要： A chemical processing microsystem useful for identifying and optimizing materials (e.g., catalysts) that enhance chemical processes or for characterizing and/or optimizing chemical processes is disclosed. The chemical processing microsystem comprises a plurality of microreactors 600 and, in a preferred embodiment, a plurality of microseparators 900 integral with the chemical processing microsystem 10. The microreactors 600 are preferably diffusion-mixed microreactors formed in a plurality of laminae that include a modular, interchangeable candidate-material array 100. The material array 100 comprises a plurality of different candidate materials (e.g., catalysts), preferably arranged at separate, individually addressable portions of a substrate (e.g., wafer). The microseparators 900 are similarly formed in a plurality of laminae that include a modular, interchangeable adsorbent array 700. The adsorbent array 700 comprises one or more adsorbents, preferably arranged at separate, individually addressable portions of a substrate to spatially correspond to the plurality of different candidate materials. Modular microfluidic distribution systems are also disclosed. The chemical processing microsystem can be integrated into a material evaluation system that enables a comprehensive combinatorial material science research program.
摘要翻译： 公开了一种用于识别和优化增强化学过程或表征和/或优化化学过程的材料（例如催化剂）的化学处理微系统。 化学处理微系统包括多个微反应器600，并且在优选实施例中是与化学处理微系统10整合的多个微分离器900.微反应器600优选地是形成在多个层中的扩散混合微反应器，其包括模块化， 材料阵列100包括多个不同的候选材料（例如，催化剂），优选地布置在基板（例如，晶片）的单独可单独寻址的部分处。 微分离器900类似地形成在包括模块化的可互换的吸附剂阵列700的多个层中。吸附剂阵列700包括一个或多个吸附剂，优选地布置在基板的分开的，可单独寻址的部分上，以在空间上对应于多个不同的 候选材料。 还公开了模块化微流体分布系统。 化学加工微系统可以整合到材料评估系统中，实现全面的组合材料科学研究计划。
-
7.发明授权Microfluidic fluid distribution manifold for use with multi-channel reactor systems 失效用于多通道反应器系统的微流体分配歧管公开(公告)号：US07758814B2
公开(公告)日：2010-07-20
申请号：US11145050
申请日：2005-06-03
CPC分类号： B01D61/18 , B01D67/0062 , B01F13/0066 , B01J2219/00351 , B01J2219/00389 , B01J2219/00747
摘要： A microfluidic fluid distribution manifold includes a common port and a plurality of fluidic channels spirally wound around the common port. Each fluidic channel connects the common port to an independent port and provides essentially the same flow resistance to a fluid flowing therethrough. A fixture for the flow restrictor allows fluid flows to be communicated between the flow restrictor and a larger system such as a parallel reactor system.
摘要翻译： 微流体流体分配歧管包括公共端口和围绕公共端口螺旋地卷绕的多个流体通道。 每个流体通道将公共端口连接到独立端口，并且为流过其中的流体提供基本相同的流动阻力。 用于限流器的夹具允许流体流在流量限制器和较大系统之间连通，例如并联反应器系统。
-
公开(公告)号：US07255474B2
公开(公告)日：2007-08-14
申请号：US10900612
申请日：2004-07-28
申请人： Peijun Cong , Shenheng Guan , Stephen Cypes , Jason Wells , H. Sam Bergh
发明人： Peijun Cong , Shenheng Guan , Stephen Cypes , Jason Wells , H. Sam Bergh
CPC分类号： G01N21/253 , B01J2219/00286 , B01J2219/00306 , B01J2219/00704 , B01J2219/00745 , B01J2219/00747 , B01L3/5027 , C40B30/08 , C40B40/18 , G01N21/0303 , G01N21/05 , G01N21/3577 , G01N35/028 , G01N2021/0346 , G01N2035/00237
摘要： A library of material samples is provided in a condition suitable for imaging using infrared (IR) spectroscopy. The samples are provided to one or more detection cells, each of the cells including or containing a reflective surface. Preferably, for imaging, an energy source (e.g. a source of infrared radiation) provides energy to the detection cells to interact with the samples. Thereafter, images (e.g., spectra) related to the samples are created based upon the interaction.
摘要翻译： 以适于使用红外（IR）光谱法进行成像的条件提供材料样品库。 将样品提供给一个或多个检测细胞，每个细胞包括或包含反射表面。 优选地，对于成像，能量源（例如，红外辐射源）向检测单元提供能量以与样品相互作用。 此后，基于相互作用创建与样本相关的图像（例如，光谱）。
-
9.发明授权Methods for identifying optimizing catalysts in parallel-flow microreactors 失效用于识别平行流微量反应器中优化催化剂的方法公开(公告)号：US06902934B1
公开(公告)日：2005-06-07
申请号：US09728732
申请日：2000-11-28
申请人： H. Sam Bergh , Shenheng Guan
发明人： H. Sam Bergh , Shenheng Guan
IPC分类号： B01F5/06 , B01J19/00 , B01L3/00 , B01L7/00 , C01B3/40 , C07C17/23 , C07C45/34 , C07C45/35 , C07C45/38 , C07C45/46 , C07C45/50 , C07C45/54 , C07C45/72 , C40B30/08 , C40B40/18 , G01N30/90 , G01N31/10 , G01N35/00 , G01N35/02
CPC分类号： B01L3/502715 , B01F5/0601 , B01F15/0264 , B01J19/0046 , B01J19/0093 , B01J2219/00286 , B01J2219/00306 , B01J2219/00308 , B01J2219/00313 , B01J2219/00317 , B01J2219/00337 , B01J2219/00351 , B01J2219/00353 , B01J2219/00389 , B01J2219/00418 , B01J2219/00452 , B01J2219/00479 , B01J2219/00495 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00635 , B01J2219/00637 , B01J2219/00641 , B01J2219/00657 , B01J2219/00659 , B01J2219/00704 , B01J2219/00707 , B01J2219/0072 , B01J2219/00745 , B01J2219/00747 , B01J2219/00759 , B01L3/5025 , B01L3/5027 , B01L3/502707 , B01L7/54 , B01L2200/0689 , B01L2200/146 , B01L2300/0864 , B01L2300/0874 , B01L2300/0887 , B01L2300/14 , B01L2300/18 , B01L2400/0487 , C01B3/40 , C07C17/23 , C07C45/34 , C07C45/35 , C07C45/38 , C07C45/46 , C07C45/54 , C07C45/72 , C40B30/08 , C40B40/18 , G01N30/90 , G01N31/10 , G01N35/028 , G01N2035/00158 , Y10T137/87885 , Y10T436/117497 , Y10T436/118339 , Y10T436/2575 , C07C47/06 , C07C47/22 , C07C47/04 , C07C47/127 , C07C49/403 , G01N30/466
摘要： A chemical processing microsystem useful for identifying and optimizing, materials (e.g., catalysts) that enhance chemical processes or for characterizing and/or optimizing chemical processes is disclosed. The chemical processing microsystem comprises a plurality of microreactors 600 and, in a preferred embodiment, a plurality of microseparators 900 integral with the chemical processing microsystem 10. The microreactors 600 are preferably diffusion-mixed microreactors formed in a plurality of laminae that include a modular, interchangeable candidate-material array 100. The material array 100 comprises a plurality of different candidate materials (e.g., catalysts), preferably arranged at separate, individually addressable portions of a substrate (e.g., wafer). The microseparators 900 are similarly formed in a plurality of laminae that include a modular, interchangeable adsorbent array 700.
摘要翻译： 公开了一种用于识别和优化用于增强化学过程或表征和/或优化化学过程的材料（例如催化剂）的化学处理微系统。 化学处理微系统包括多个微反应器600，并且在优选实施例中是与化学处理微系统10整合的多个微分离器900.微反应器600优选地是形成在多个层中的扩散混合微反应器，其包括模块化， 材料阵列100包括多个不同的候选材料（例如，催化剂），优选地布置在基板（例如，晶片）的单独可单独寻址的部分处。 微分离器900类似地形成在包括模块化的可互换吸附剂阵列700的多个层中。
-
公开(公告)号：US06890493B1
公开(公告)日：2005-05-10
申请号：US09728263
申请日：2000-11-28
申请人： H. Sam Bergh , Shenheng Guan
发明人： H. Sam Bergh , Shenheng Guan
IPC分类号： B01F5/06 , B01J19/00 , B01L3/00 , B01L7/00 , C01B3/40 , C07C17/23 , C07C45/34 , C07C45/35 , C07C45/38 , C07C45/46 , C07C45/50 , C07C45/54 , C07C45/72 , C40B30/08 , C40B40/18 , G01N30/90 , G01N31/10 , G01N35/00 , G01N35/02
CPC分类号： B01L3/502715 , B01F5/0601 , B01F15/0264 , B01J19/0046 , B01J19/0093 , B01J2219/00286 , B01J2219/00306 , B01J2219/00308 , B01J2219/00313 , B01J2219/00317 , B01J2219/00337 , B01J2219/00351 , B01J2219/00353 , B01J2219/00389 , B01J2219/00418 , B01J2219/00452 , B01J2219/00479 , B01J2219/00495 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00635 , B01J2219/00637 , B01J2219/00641 , B01J2219/00657 , B01J2219/00659 , B01J2219/00704 , B01J2219/00707 , B01J2219/0072 , B01J2219/00745 , B01J2219/00747 , B01J2219/00759 , B01L3/5025 , B01L3/5027 , B01L3/502707 , B01L7/54 , B01L2200/0689 , B01L2200/146 , B01L2300/0864 , B01L2300/0874 , B01L2300/0887 , B01L2300/14 , B01L2300/18 , B01L2400/0487 , C01B3/40 , C07C17/23 , C07C45/34 , C07C45/35 , C07C45/38 , C07C45/46 , C07C45/54 , C07C45/72 , C40B30/08 , C40B40/18 , G01N30/90 , G01N31/10 , G01N35/028 , G01N2035/00158 , Y10T137/87885 , Y10T436/117497 , Y10T436/118339 , Y10T436/2575 , C07C47/06 , C07C47/22 , C07C47/04 , C07C47/127 , C07C49/403 , G01N30/466
摘要： A chemical processing microsystem useful for identifying and optimizing materials (e.g., catalysts) that enhance chemical processes or for characterizing and/or optimizing chemical processes is disclosed. The chemical processing microsystem comprises a plurality of microreactors 600 and, in a preferred embodiment, a plurality of microseparators 900 integral with the chemical processing microsystem 10. The microreactors 600 are preferably diffusion-mixed microreactors formed in a plurality of laminae that include a modular, interchangeable candidate-material array 100. The material array 100 comprises a plurality of different candidate materials (e.g., catalysts), preferably arranged at separate, individually addressable portions of a substrate (e.g., wafer). The microseparators 900 are similarly formed in a plurality of laminae that include a modular, interchangeable adsorbent array 700. The adsorbent array 700 comprises one or more adsorbents, preferably arranged at separate, individually addressable portions of a substrate to spatially correspond to the plurality of different candidate materials. Modular microfluidic distribution systems are also disclosed. The chemical processing microsystem can be integrated into a material evaluation system that enables a comprehensive combinatorial material science research program.
摘要翻译： 公开了一种用于识别和优化增强化学过程或表征和/或优化化学过程的材料（例如催化剂）的化学处理微系统。 化学处理微系统包括多个微反应器600，并且在优选实施例中包括与化学处理微系统10集成的多个微分离器900。 微反应器600优选地是形成在多个层中的扩散混合微反应器，其包括模块化的，可互换的候选材料阵列100。 材料阵列100包括多个不同的候选材料（例如，催化剂），优选地布置在基板（例如，晶片）的单独可寻址部分处。 微分离器900类似地形成在包括模块化的可互换吸附剂阵列700的多个层中。 吸附剂阵列700包括一个或多个吸附剂，优选地布置在基板的分开的，可单独寻址的部分上，以在空间上对应于多种不同的候选材料。 还公开了模块化微流体分布系统。 化学加工微系统可以整合到材料评估系统中，实现全面的组合材料科学研究计划。
-
-
-
-
-
-
-
-
-
搜索结果
16 条记录 (耗时 0.048 秒)
