Apparatus for transfer of an array of liquids and methods for manufacturing same
    121.
    发明申请
    Apparatus for transfer of an array of liquids and methods for manufacturing same 审中-公开
    用于转移液体阵列的装置及其制造方法

    公开(公告)号:US20040129676A1

    公开(公告)日:2004-07-08

    申请号:US10337834

    申请日:2003-01-07

    发明人: Roy H. Tan

    摘要: A method for producing an apparatus for transferring small amounts of liquids includes bonding a plurality of parallel fibers having plural coaxial layers into a bundle, slicing the bundle of parallel fibers in planes perpendicular to the direction of the fibers to form two opposite, planar surfaces, and selectively etching the fiber layers to create etched wells in the fibers at one of the planar surfaces. The etched wells are in fluid communication with corresponding capillary nozzles of the fibers that extend to an opposite one of the planar surfaces. Various apparatus configurations of the present invention include liquid transfer devices manufactured utilizing one or more of the various method configurations of the present invention. By way of example only, a bundle of three-layer optical fibers or a bundle of hollow two-layer optical fibers may be utilized to produce a liquid transfer device.

    摘要翻译: 一种用于生产用于传送少量液体的装置的方法包括将多个具有多个同轴层的平行纤维粘合成束,将平行纤维束切割成与纤维方向垂直的平面,以形成两个相对的平坦表面, 并选择性地蚀刻纤维层,以在其中一个平面表面的纤维中产生蚀刻孔。 蚀刻的孔与延伸到相对的一个平面表面的纤维的相应毛细管喷嘴流体连通。 本发明的各种装置结构包括使用本发明的各种方法构造中的一种或多种制造的液体转移装置。 仅作为示例,可以使用一束三层光纤或一束中空双层光纤来产生液体转移装置。

    Method for producing a microarray
    125.
    发明申请
    Method for producing a microarray 审中-公开
    微阵列的制备方法

    公开(公告)号:US20040018613A1

    公开(公告)日:2004-01-29

    申请号:US10616160

    申请日:2003-07-09

    发明人: Tomoaki Shoji

    摘要: Microarray is produced by the method comprising the steps of forming a droplet of a liquid sample containing a biological substance at a pouring port of a micropipette by ejecting a predetermined amount of the liquid sample from the micropipette, supporting the micropipette at a position where the droplet formed at the pouring port can contact with a substrate, and transferring the droplet formed at the pouring port to the substrate, thereby spotting the sample on the substrate. The microarray has a plurality of visually identifiable spots of samples on the substrate.

    摘要翻译: 微阵列通过以下方法制备:包括以下步骤:通过从微量移液管喷射预定量的液体样品,在微量移液管的注入口处形成含有生物物质的液体样品的液滴,将微量移液管支撑在液滴 在浇注口处形成的可以与基板接触,并且将在浇注口处形成的液滴转移到基板上,从而将样品点在基板上。 微阵列在基底上具有多个可视识别的样品斑点。