Microbial succinic acid producers and purification of succinic acid
    131.
    发明授权
    Microbial succinic acid producers and purification of succinic acid 有权
    微生物琥珀酸生产商和琥珀酸的纯化

    公开(公告)号:US09023632B2

    公开(公告)日:2015-05-05

    申请号:US14150206

    申请日:2014-01-08

    申请人: BASF SE

    摘要: The present invention relates to bacterial strains, capable of utilizing glycerol as a carbon source for the fermentative production of succinic acid, wherein said strains are genetically modified so that they comprise a deregulation of their endogenous pyruvate-formate-lyase enzyme activity, as well as to methods of producing organic acids, in particular succinic acid, by making use of such microorganism. The present invention also relates to the downstream processing of the produced organic acids by cation exchange chromatography.

    摘要翻译: 本发明涉及能够利用甘油作为发酵生产琥珀酸的碳源的细菌菌株,其中所述菌株被遗传修饰,使得它们包含其内源性丙酮酸 - 甲酸裂解酶活性的失调,以及 涉及通过利用这种微生物生产有机酸,特别是琥珀酸的方法。 本发明还涉及通过阳离子交换层析对所生产的有机酸的下游加工。

    Controlled activation of the reuterin-production machinery of Lactobacillus
    132.
    发明授权
    Controlled activation of the reuterin-production machinery of Lactobacillus 有权
    乳酸杆菌的罗伊氏菌素生产机械的控制活化

    公开(公告)号:US08945534B2

    公开(公告)日:2015-02-03

    申请号:US14070814

    申请日:2013-11-04

    申请人: Stefan Roos

    发明人: Stefan Roos

    摘要: Methods for the controlled activation of the reuterin-production machinery of Lactobacillus reuteri by adding glycerol and other substances during the manufacture of cell-cultures and keeping the produced reuterin in the bacterial cell during preservation and storage. In particular this invention relates to the manufacture of large amounts of L. reuteri that are loaded with reuterin, and the use of such loaded bacteria for applications such as prevention and treatment of diseases, for food applications and the like.

    摘要翻译: 通过在制备细胞培养物期间加入甘油和其他物质并在保存和储存期间将产生的罗伊氏菌素保持在细菌细胞中来控制罗伊氏乳杆菌产生罗伊氏乳杆菌生产机器的方法。 特别地,本发明涉及装载有罗伊氏菌素的大量罗伊氏乳杆菌的制造,以及这种负载细菌用于诸如预防和治疗疾病,食品应用等的应用。

    Apparatus for the treatment of lignocellulosic materials
    138.
    发明授权
    Apparatus for the treatment of lignocellulosic materials 失效
    用于处理木质纤维素材料的装置

    公开(公告)号:US5266487A

    公开(公告)日:1993-11-30

    申请号:US957592

    申请日:1992-10-06

    摘要: An apparatus is disclosed for treating lignocellulosic materials, comprising an enzymatic conversion zone adapted to enzymatically convert alcohol to aldehyde and hydrogen peroxide, a delignification zone, a device for transferring an effluent comprising aqueous hydrogen peroxide from the conversion zone to the delignification zone, a chopper for adding chopped lignocellulosic material to the delignification zone, a separator for separating solid delignified material in the delignification zone from a liquid, and a fermenter adapted to grow alcohol oxidase-producing yeast, and means for transferring alcohol oxidase from the fermenter into the conversion zone.

    摘要翻译: 公开了一种用于处理木质纤维素材料的装置,其包括适于将醇转化为醛和过氧化氢的酶转化区,脱木素带,用于将包含过氧化氢水溶液的转移物从转化区转移到脱木素区的装置,切碎机 用于向脱木素带中加入切碎的木质纤维素材料,用于将脱木质区中的固体脱木素与液体分离的分离器和适于生长醇氧化酶生产酵母的发酵罐,以及将醇氧化酶从发酵罐转移到转化区 。