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    Variable control of electroosmotic and/or electrophoretic forces within a fluid-containing structure via electrical forces
    31.
    发明授权
    Variable control of electroosmotic and/or electrophoretic forces within a fluid-containing structure via electrical forces 有权
    通过电力可变控制含液体结构内的电渗和/或电泳力

    公开(公告)号：US06413401B1

    公开(公告)日：2002-07-02

    申请号：US09214127

    申请日：1999-07-29

    申请人： Calvin Y. H. Chow ,  J. Wallace Parce

    发明人： Calvin Y. H. Chow ,  J. Wallace Parce

    IPC分类号： G01N2726

    CPC分类号： G01N27/44791 ,  G01N27/44713 ,  G01N27/44752 ,  G01N27/44773 ,  Y10S366/02 ,  Y10T29/49002

    摘要： In a microfluidic system using electrokinetic forces, the present invention uses electrical current or electrical parameters, other than voltage, to control the movement of fluids through the channels of the system. Time-multiplexed power supplies also provide further control over fluid movement by varying the voltage on an electrode connected to a fluid reservoir of the microfluidic system, by varying the duty cycle during which the voltage is applied to the electrode, or by a combination of both. A time-multiplexed power supply can also be connected to more than one electrode for a savings in cost.

    摘要翻译： 在使用电动力的微流体系统中，本发明使用除电压之外的电流或电气参数来控制流体通过系统的通道的运动。 时间复用电源还通过改变连接到微流体系统的流体存储器的电极上的电压，通过改变电压施加到电极的占空比或两者的组合来提供对流体运动的进一步控制 。 时间复用电源也可以连接到多个电极以节省成本。

    High throughput microfluidic systems and methods
    32.
    发明授权
    High throughput microfluidic systems and methods 有权
    高通量微流体系统和方法

    公开(公告)号：US6132685A

    公开(公告)日：2000-10-17

    申请号：US132096

    申请日：1998-08-10

    申请人： Joseph E. Kercso ,  Steven A. Sundberg ,  Jeffrey A. Wolk ,  Andrew W. Toth ,  Calvin Y. H. Chow ,  J. Wallace Parce

    发明人： Joseph E. Kercso ,  Steven A. Sundberg ,  Jeffrey A. Wolk ,  Andrew W. Toth ,  Calvin Y. H. Chow ,  J. Wallace Parce

    IPC分类号： G01N35/00 ,  G01N35/02

    CPC分类号： G01N35/028 ,  G01N2035/00148 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/119163 ,  Y10T436/25625 ,  Y10T436/2575

    摘要： The invention provides improved systems, devices, and methods for analyzing a large number of sample compounds contained in standard multiwell microtiter plates or other array structures. The multiwell plates travel along a conveyor system to a test station having a microfluidic device. At the test station, each plate is removed from the conveyor and the wells of the multiwell plate are sequentially aligned with an input port of the microfluidic device. After at least a portion of each sample has been input into the microfluidic channel system, the plate is returned to the conveyor system. Pre and/or post testing stations may be disposed along the conveyor system, and the use of an X-Y-Z robotic arm and novel plate support bracket allows each of the samples in the wells to be input into the microfluidic network through a probe affixed to a microfluidic chip. A clamshell structure having a hinged lid can releasably support the chip while providing and/or accommodating the electrical, optical, structural, and other interface connections between the microfluidic device and the surrounding system.

    摘要翻译： 本发明提供用于分析标准多孔微量滴定板或其它阵列结构中所含的大量样品化合物的改进的系统，装置和方法。 多孔板沿传送系统行进到具有微流体装置的测试台。 在试验台，每个板从输送机上取出，多孔板的孔依次与微流体装置的输入端对准。 在每个样品的至少一部分已经被输入到微流体通道系统中之后，板返回到输送系统。 可以沿输送机系统布置前后测试站，并且使用XYZ机器人臂和新的板支撑支架允许孔中的每个样品通过固定在微流体上的探针输入微流体网络 芯片。 具有铰接盖的蛤壳结构可以可释放地支撑芯片，同时提供和/或容纳微流体装置和周围系统之间的电，光学，结构和其它界面连接。