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    Device And Method For Transferring A Target Between Locations
    52.
    发明申请
    Device And Method For Transferring A Target Between Locations 审中-公开
    在地点之间转移目标的装置和方法

    公开(公告)号：US20150196907A1

    公开(公告)日：2015-07-16

    申请号：US14154695

    申请日：2014-01-14

    申请人： Wisconsin Alumni Research Foundation

    发明人： David J. Beebe ,  Ben P. Casavant ,  David J. Guckenberger ,  Scott M. Berry

    IPC分类号： B01L3/00 ,  C12Q1/68 ,  B01L99/00

    CPC分类号： B01L3/0268 ,  B01L3/50825 ,  B01L3/5088 ,  B01L3/563 ,  B01L2200/025 ,  B01L2200/0657 ,  B01L2200/0668 ,  B01L2300/042 ,  B01L2400/021 ,  B01L2400/043

    摘要： A device and method are proved for transferring a target from a first location to a second location. The target is bound to solid phase substrate to form a target bound solid phase substrate. The device includes transfer surface for receiving the target bound solid phase substrate thereon for transfer. The transfer surface movable between a first position wherein the transfer surface is aligned with the first location and spaced therefrom by a distance and a second position wherein the transfer surface is aligned with the second location. An alignment structure aligns the transfer surface with respect to the second location, with the transfer surface in the second position. A force is movable between an attraction position wherein the target bound solid phase substrate are drawn toward the transfer surface and a discharge position wherein the target bound solid phase substrate are free of the force.

    摘要翻译： 证明了将目标从第一位置转移到第二位置的装置和方法。 目标与固相底物结合形成目标结合的固相底物。 该装置包括用于接收其上的目标结合固相基板用于转印的转印表面。 所述转印表面可在第一位置和第二位置之间移动，所述第一位置与所述第一位置对准并且与所述第一位置间隔开距离和所述第二位置，其中所述转印表面与所述第二位置对准。 对准结构将转印表面相对于第二位置对齐，转印表面处于第二位置。 力可以在其中将目标结合的固相衬底拉向转移表面的吸引位置和其中靶结合的固相衬底没有力的放电位置之间移动。

    Separating method and an apparatus performing such a method
    55.
    发明授权
    Separating method and an apparatus performing such a method 有权
    分离方法和执行这种方法的装置

    公开(公告)号：US08129174B2

    公开(公告)日：2012-03-06

    申请号：US10502849

    申请日：2003-02-12

    申请人： Anders Alderborn ,  David Peterson ,  Bjorn Ingemarsson ,  Anna-Lotta Schiller

    发明人： Anders Alderborn ,  David Peterson ,  Bjorn Ingemarsson ,  Anna-Lotta Schiller

    IPC分类号： C12M1/34 ,  C12M3/00 ,  C12M1/00 ,  G01N15/06 ,  G01N33/00

    CPC分类号： C12N15/1017 ,  B01L3/021 ,  B01L3/5085 ,  B01L2200/0657 ,  B01L2300/0681 ,  B01L2400/049 ,  C12N15/10 ,  G01N33/54386

    摘要： A method for separating carriers from a solution, the carriers being adapted to have biomolecules, such as DNA, RNA, proteins, polypeptides or carbohydrates attached thereto. The method includes the steps of introducing a tubular member (13) into a receptacle which holds a solution containing the carriers immersing an end portion of the tubular member in the solution attracting and holding the carriers to the end portion and removing the tubular member together with the held carriers from the solution. The attracting and holding step includes the step of providing an under-pressure within the tubular member so as to attract and hold the carriers to a filter (25) being disposed in the end portion of the tubular member. The invention also relates to an apparatus (10) performing such a method.

    摘要翻译： 从溶液中分离载体的方法，载体适于具有附着于其上的生物分子，例如DNA，RNA，蛋白质，多肽或碳水化合物。 该方法包括以下步骤：将管状构件（13）引入容器中，该容器保持含有载体的溶液，该溶液将管状构件的端部浸入溶液中，吸附并将载体保持在端部，并将管状构件与 来自解决方案的持有运营商。 吸引和保持步骤包括在管状构件内提供负压以便将载体吸引并保持在设置在管状构件的端部中的过滤器（25）的步骤。 本发明还涉及执行这种方法的装置（10）。

    Method and apparatus for manufacturing beads array chip
    57.
    发明授权
    Method and apparatus for manufacturing beads array chip 有权
    珠阵列芯片的制造方法和装置

    公开(公告)号：US07820112B2

    公开(公告)日：2010-10-26

    申请号：US12289021

    申请日：2008-10-17

    申请人： Hideyuki Noda ,  Yoshinobu Kohara

    发明人： Hideyuki Noda ,  Yoshinobu Kohara

    IPC分类号： B01L3/02

    CPC分类号： B01L3/0289 ,  B01J19/0046 ,  B01J2219/00459 ,  B01J2219/00468 ,  B01J2219/005 ,  B01J2219/00666 ,  B01J2219/00722 ,  B01L2200/0657 ,  C40B40/06 ,  Y10T436/119163 ,  Y10T436/2575

    摘要： A bead array chip manufacturing process for manufacturing a bead array chip having plural kinds of beads arrayed in a predetermined order in, in a container having a plurality of first channels disposed substantially in parallel with each other and a second channel crossing the plurality of first channels, each of the first channels. The process including lowering a capillary inserted in the second channel and sucking and retaining one bead in one end of the capillary, lifting the capillary to position the beads retained in the one end of the capillary in a desired channel of the plurality of first channels, terminating the suction of the capillary, and generating a uniflow of a fluid in the second channel.

    摘要翻译： 一种珠阵列芯片制造方法，用于制造具有以预定顺序排列的多种珠的珠阵列芯片，所述珠状阵列芯片具有彼此大致平行设置的多个第一通道的容器和与所述多个第一通道交叉的第二通道 ，每个第一个通道。 该过程包括降低插入在第二通道中的毛细管并吸入并保持毛细管的一端中的一个珠粒，提升毛细管以将保留在毛细管一端的珠子定位在多个第一通道的期望通道中， 终止毛细管的抽吸，并在第二通道中产生流体的一体。