Method of deposition a dry powder and dispensing device
    1.
    发明授权
    Method of deposition a dry powder and dispensing device 失效
    沉积干粉和分配装置的方法

    公开(公告)号:US6146685A

    公开(公告)日:2000-11-14

    申请号:US187092

    申请日:1998-11-05

    摘要: A dry powder, for example, a medicament for an inhaler, comprises elongated particles with an aspect ratio sufficient to cause the particles to be bound to a preferably metal or non-metallic sheet material substrate at the particle tips by electrostatic deposition and for aligning a plurality of particles with their major axes aligned normal to the substrate and oriented tip-to-tip. Particles deposited form a low density, high relative void deposition to minimize attractive forces between the particles. This minimizes agglomeration and bonding forces to the substrate facilitating the release of a powdered medicament in an inhaler. Medicament dosages in a substrate pocket are covered by a sealing layer. An embodiment of a drug dosage inhaler substrate and inhaler is disclosed.

    摘要翻译: 干粉,例如用于吸入器的药物,包括细长的颗粒,其长宽比足以使得颗粒通过静电沉积而在颗粒尖端处与优选金属或非金属片材基材结合,并且用于对准 多个颗粒的主轴与衬底垂直对齐并且取向尖端到尖端。 沉积的颗粒形成低密度,高相对空隙沉积,以最小化颗粒之间的吸引力。 这最小化对基质的附聚和结合力,有助于在吸入器中释放粉末状药物。 衬底袋中的药物剂量被密封层覆盖。 公开了药物剂量吸入器基质和吸入器的实施方案。

    Dry powder dispensing device
    2.
    发明授权
    Dry powder dispensing device 失效
    干粉分配装置

    公开(公告)号:US06397840B1

    公开(公告)日:2002-06-04

    申请号:US09588090

    申请日:2000-06-06

    IPC分类号: A61M1502

    摘要: A dry powder, for example, a medicament for an inhaler, comprises elongated particles with an aspect ratio sufficient to cause the particles to be bound to a preferably metal or non-metallic sheet material substrate at the particle tips by electrostatic deposition and for aligning a plurality of particles with their major axes aligned normal to the, substrate and oriented tip-to-tip. Particles deposited form a low density, high relative void deposition to minimize attractive forces between the particles. This minimizes agglomeration and bonding forces to the substrate facilitating the release of a powdered medicament in an inhaler. Medicament dosages in a substrate pocket are covered by a sealing layer. An embodiment of a drug dosage inhaler substrate and inhaler is disclosed.

    摘要翻译: 干粉,例如用于吸入器的药物,包括细长的颗粒,其长宽比足以使得颗粒通过静电沉积在颗粒尖端处与优选的金属或非金属片材基材结合,并且用于使 多个颗粒的主轴与基板垂直对准并定向到尖端。 沉积的颗粒形成低密度,高相对空隙沉积,以最小化颗粒之间的吸引力。 这最小化对基质的附聚和结合力,有助于在吸入器中释放粉末状药物。 衬底袋中的药物剂量被密封层覆盖。 公开了药物剂量吸入器基质和吸入器的实施方案。

    Medicament dry powder inhaler dispensing device
    4.
    发明授权
    Medicament dry powder inhaler dispensing device 失效
    药物干粉吸入器分配装置

    公开(公告)号:US06752148B1

    公开(公告)日:2004-06-22

    申请号:US09623937

    申请日:2000-09-01

    IPC分类号: A61M1500

    摘要: An inhaler disc cartridge comprises a carrier disc with radially outwardly extending resilient fingers, each with a medicament powder dosage. A sealing disc and an indexing ring are bonded to the disc. A cam sequentially and manually deflects a selected finger causing it to snap against an anvil to release the dosage by momentum energy transfer. In other embodiments, a cassette includes a carrier substrate reel of deposited powder dosages with a dosage sealing tape. The substrate comprises a belt with a plurality of transversely extending triangular fingers, each finger tip with a dosage thereon. Each finger is snapped in sequence against an anvil while a clamp secures the belt as the fingers are deflected. The spring fingers are corrugated in one embodiment cooperating with an anvil having channels and a device for inducing agglomeration breakup air streams through the channels. Other embodiments are for impact deflection of a dosage carrying substrate in a cartridge or cassette against an anvil to release the dosages.

    摘要翻译: 一个吸入式盘盒包括一个具有径向向外延伸的弹性指状物的承载盘,每个都带有药物粉末剂量。 密封盘和分度环结合到盘上。 凸轮顺序地并且手动地偏转所选择的手指,使其与砧座卡扣以通过动量能量传递释放剂量。 在其他实施例中,盒包括具有剂量密封带的沉积的粉末剂量的载体衬底卷轴。 衬底包括具有多个横向延伸的三角形指状物的带,每个指尖具有其上的剂量。 每个手指按照砧座顺序扣合,同时当手指偏转时,夹具固定皮带。 在一个实施例中,弹簧指状物是波纹状的,与具有通道的砧座配合,以及用于通过通道引起团聚分解空气流的装置。 其他实施方案是用于将剂量携带衬底在药筒或药盒中抵抗砧座的冲击挠曲以释放剂量。

    Modular display system
    5.
    发明授权
    Modular display system 有权
    模块化显示系统

    公开(公告)号:US06611241B1

    公开(公告)日:2003-08-26

    申请号:US09200081

    申请日:1998-11-25

    IPC分类号: G09G500

    摘要: Large visual displays are comprised of an array of smaller display devices or modules, each of which displays a portion of the image to be displayed so that together the array of smaller display devices displays the complete image. Unlike conventional large displays which necessarily seek to minimize the edge areas of the smaller display elements that do not display an image so as to minimize the “seams” or gaps between the image portions, the present display device projects image portions scanned from less than the entire display area of the smaller display devices in an array to create an image on a substantially flat panel that is substantially free of visual “seams” or gaps between the image portions. Thus the display device may employ display elements that do not have narrow edges and that are not contiguous to generate overlapping sub-images. Image pixels in what would otherwise be “seams” or gaps are generated from the image data and are displayed in proper position and brightness in the displayed image, such as in the overlap regions of overlapping sub-images. Where the scanning beams are electron beams, the flat panel is a faceplate that includes phosphors that are excited by the electron beam to produce light, and where the beams are light beams, the flat panel is a distributor of light, such as a diffuser panel.

    摘要翻译: 大型视觉显示器由较小的显示设备或模块的阵列组成,每个显示设备或模块显示要显示的图像的一部分,使得较小显示设备的阵列一起显示完整的图像。 与传统的大型显示器不同,传统的大型显示器必然寻求使不显示图像的较小显示元件的边缘区域最小化,以使图像部分之间的“接缝”或间隙最小化,本显示装置投影从小于 在阵列中的较小显示设备的整个显示区域,以在基本上平坦的面板上创建基本上没有视觉“接缝”或图像部分之间的间隙的图像。 因此,显示装置可以采用不具有窄边缘并且不连续以产生重叠子图像的显示元件。 否则将从图像数据生成“接缝”或间隙的图像像素,并且显示在显示图像中的适当位置和亮度中,例如在重叠的子图像的重叠区域中。 在扫描光束是电子束的情况下,平板是包括由电子束激发以产生光的荧光体的面板,并且其中光束是光束,平板是光的分布器,例如漫射板 。