Melonine bisindole compounds, pharmaceutical compositions, preparation method and use thereof
    5.
    发明授权
    Melonine bisindole compounds, pharmaceutical compositions, preparation method and use thereof 有权
    甜菜双吲哚化合物,药物组合物,其制备方法和用途

    公开(公告)号:US09163035B2

    公开(公告)日:2015-10-20

    申请号:US13508277

    申请日:2010-11-04

    摘要: The present invention relates to pharmaceutical technical field, to melonine bisindole compounds, pharmaceutical compositions thereof, and preparation methods thereof. Specifically, the present invention relates to melonine bisindole compounds of Formula I, pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts thereof. The present invention further relates to method for preparing the melonine bisindole compounds of Formula I or pharmaceutically acceptable salts thereof, and the use of the melonine bisindole compounds of Formula I or pharmaceutically acceptable salts thereof in the manufacture of a medicament for the treatment or prophylaxis of cancers.

    摘要翻译: 本发明涉及药用技术领域,甜瓜双吲哚化合物及其药物组合物及其制备方法。 具体地,本发明涉及式I的甜瓜双吲哚化合物,其药学上可接受的盐,包含该化合物或其药学上可接受的盐的药物组合物。 本发明还涉及制备式I的甜菜双吲哚化合物或其药学上可接受的盐的方法,以及式I的甜瓜双吲哚化合物或其药学上可接受的盐在制备用于治疗或预防 癌症

    Configuration of high-voltage semiconductor power device to achieve three dimensional charge coupling
    8.
    发明授权
    Configuration of high-voltage semiconductor power device to achieve three dimensional charge coupling 有权
    配置高压半导体功率器件实现三维电荷耦合

    公开(公告)号:US08461004B2

    公开(公告)日:2013-06-11

    申请号:US13066373

    申请日:2011-04-12

    IPC分类号: H01L21/336

    摘要: This invention discloses semiconductor device that includes a top region and a bottom region with an intermediate region disposed between said top region and said bottom region with a controllable current path traversing through the intermediate region. The semiconductor device further includes a trench with padded with insulation layer on sidewalls extended from the top region through the intermediate region toward the bottom region wherein the trench includes randomly and substantially uniformly distributed nano-nodules as charge-islands in contact with a drain region below the trench for electrically coupling with the intermediate region for continuously and uniformly distributing a voltage drop through the current path.

    摘要翻译: 本发明公开了一种半导体器件,其包括顶部区域和底部区域,其中间区域设置在所述顶部区域和所述底部区域之间,并具有穿过所述中间区域的可控电流通路。 所述半导体器件还包括沟槽,该沟槽在从所述顶部区域延伸穿过所述中间区域朝向所述底部区域的侧壁上被填充有绝缘层,其中所述沟槽包括随机均匀分布的纳米结节,作为与下面的漏极区域接触的电荷岛 用于与中间区域电耦合的沟槽,用于通过电流路径连续均匀地分配电压降。

    Micro surface mount device packaging
    9.
    发明授权
    Micro surface mount device packaging 有权
    微表面贴装装置包装

    公开(公告)号:US08450151B1

    公开(公告)日:2013-05-28

    申请号:US13303053

    申请日:2011-11-22

    摘要: A variety of improved approaches for packaging integrated circuits are described. In one described approach, a multiplicity of dice are mounted on a carrier (e.g., a plastic carrier). Each die has a plurality of wire bonded contact studs secured to its associated I/O pads. An encapsulant is applied over the carrier to cover the dice and at least portions of the contact studs to form an encapsulant carrier structure. After the encapsulant has been applied, a first surface of the encapsulant and the contact studs are ground such that exposed portions of the contact studs are smooth and substantially co-planar with the encapsulant. In some embodiments, a redistribution layer is formed over the encapsulant carrier structure and solder bumps are attached to the redistribution layer. A contact encapsulant layer is applied over the encapsulant carrier structure to provide extra mechanical support for the resulting packages.

    摘要翻译: 描述了用于封装集成电路的各种改进方法。 在所描述的方法中,多个骰子安装在载体(例如,塑料载体)上。 每个管芯具有固定到其相关联的I / O焊盘的多个引线接合柱塞。 在载体上施加密封剂以覆盖骰子和至少部分接触柱以形成密封剂载体结构。 在施加了密封剂之后,密封剂的第一表面和接触柱被研磨,使得接触柱的暴露部分与密封剂平滑并且基本上共面。 在一些实施例中,在密封剂载体结构上方形成再分配层,并且焊料凸块附着到再分配层。 接触密封剂层施加在密封剂载体结构上以为所得到的包装提供额外的机械支撑。

    MICRO SURFACE MOUNT DEVICE PACKAGING
    10.
    发明申请
    MICRO SURFACE MOUNT DEVICE PACKAGING 有权
    微表面装置包装

    公开(公告)号:US20130127043A1

    公开(公告)日:2013-05-23

    申请号:US13303053

    申请日:2011-11-22

    IPC分类号: H01L23/488 H01L21/78

    摘要: A variety of improved approaches for packaging integrated circuits are described. In one described approach, a multiplicity of dice are mounted on a carrier (e.g., a plastic carrier). Each die has a plurality of wire bonded contact studs secured to its associated I/O pads. An encapsulant is applied over the carrier to cover the dice and at least portions of the contact studs to form an encapsulant carrier structure. After the encapsulant has been applied, a first surface of the encapsulant and the contact studs are ground such that exposed portions of the contact studs are smooth and substantially co-planar with the encapsulant. In some embodiments, a redistribution layer is formed over the encapsulant carrier structure and solder bumps are attached to the redistribution layer. A contact encapsulant layer is applied over the encapsulant carrier structure to provide extra mechanical support for the resulting packages.

    摘要翻译: 描述了用于封装集成电路的各种改进方法。 在所描述的方法中,多个骰子安装在载体(例如,塑料载体)上。 每个管芯具有固定到其相关联的I / O焊盘的多个引线接合柱塞。 在载体上施加密封剂以覆盖骰子和至少部分接触柱以形成密封剂载体结构。 在施加了密封剂之后,密封剂的第一表面和接触柱被研磨,使得接触柱的暴露部分与密封剂平滑并且基本上共面。 在一些实施例中,在密封剂载体结构上方形成再分配层,并且焊料凸块附着到再分配层。 接触密封剂层施加在密封剂载体结构上以为所得到的包装提供额外的机械支撑。