摘要:
Compounds useful in pest control, represented by the general formula [I] wherein A, B and C are each hydrogen, halogeno, trifluoro- methylsulfonyloxy, alkyl, alkylthioalkyl, or the like; X is a single bond, methylene, ethylene, or the like;R and R are each hydrogen, alkyl, an aldehyde group, alkylcarbonyl, alkoxycarbonyl, or the like; R is hydrogen, hydroxyl, alkyl, alkoxy, alkylcarbonyl, or the like; and l, m and n are each an integer of 1 to 5, or the like.
摘要翻译:用于病虫害防治的化合物,由通式[I]表示,其中A,B和C各自为氢,卤代,三氟甲基磺酰氧基,烷基,烷硫基烷基等; X是单键,亚甲基,亚乙基等; R 1和R 2各自为氢,烷基,醛基,烷基羰基,烷氧基羰基等; R 3是氢,羟基,烷基,烷氧基,烷基羰基等; l,m和n分别为1〜5的整数等。
摘要:
A medical composition containing, as an active constituent, a nitroetheneamine derivative represented by formula (I) wherein R is a hydrogen atom, an optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkenyl, aryl or heterocyclic group, or a cyano group; R and R may be each a hydrogen atom, an optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkenyl, aryl or heterocyclic group, or -A-R (wherein A is S, SO, SO2, SO3, CO or CO2, and R is a hydrogen atom, an optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkenyl, aryl or heterocyclic group), or may form N=CR R (wherein R and R are each a hydrogen atom, an optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkenyl, aryl or heterocyclic group, an alkoxy or aryloxy group, a cyano group, a nitro group, or -A-R ); R and R may be each a hydrogen atom, an optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkenyl, aryl or heterocyclic group, an alkoxy group, an amino group, an aryloxy group, -A-R , a cyano group, an ester group or a hydroxyl group, or may form N=CR R ; R is a hydrogen atom, a nitro group, a cyano group, -A-R , an optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkenyl, aryl or heterocyclic group, an alkoxy group, an amino group, or a halogen atom; and further R , R , R , R and R may form a ring containing or not containing a heteroatom, or a salt thereof as an active constituent.
摘要翻译:含有作为活性成分的式(I)表示的硝基乙烯胺衍生物的化合物,其中R 1为氢原子,任意取代的烷基,烯基,炔基,环烷基,环烯基,芳基或杂环基或氰基 组; R 2和R 3可以各自为氢原子,任选取代的烷基,烯基,炔基,环烷基,环烯基,芳基或杂环基或-AR 7(其中A为S,SO,SO 2, SO 3,CO或CO 2,R 7是氢原子,任选取代的烷基,烯基,炔基,环烷基,环烯基,芳基或杂环基),或可以形成N = CR 8 R 9 R 8和R 9各自为氢原子,任选取代的烷基,烯基,炔基,环烷基,环烯基,芳基或杂环基,烷氧基或芳氧基,氰基,硝基或-AR <7>); R 4和R 5可以各自为氢原子,任选取代的烷基,烯基,炔基,环烷基,环烯基,芳基或杂环基,烷氧基,氨基,芳氧基,-AR 7 或氰基,酯基或羟基,或者可以形成N = CR 8 R 9; R 6是氢原子,硝基,氰基,-AR 7,任选取代的烷基,烯基,炔基,环烷基,环烯基,芳基或杂环基,烷氧基,氨基或 卤素原子; 并且进一步的R 1,R 2,R 3,R 4和R 5可以形成含有或不含有杂原子的环或其盐作为活性成分。
摘要:
Novel amidino-urea 5-HT7 receptor ligands, methods of preparing such ligands, intermediate compounds useful in the preparation of the receptor ligands, pharmaceutical compositions comprising the receptor ligands, and methods of treating sleep disorders, pain, depression, and schizophrenia employing the receptor ligands are disclosed. The receptor ligands have formula (1): wherein the formula variables are as defined herein, and pharmaceutically acceptable salts, solvates, active metabolites, or prodrugs thereof.
摘要:
Novel alkyl ketone compounds having potent cytotoxic activity are described as antitumor agents and are particularly effective against leukemia and breast tumor cells. The compounds of the invention have formula (I), wherein R1-R4, X and p have the meanings given in the description.
摘要:
Compounds of Formula (I), and their agriculturally suitable salts, are disclosed which are useful as arthropodicides, wherein R , R , R , R , R , m and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula (I) and a method for controlling anthropods which involves contacting the arthropods or their environment with an effective amount of a compound of Formula (I).
摘要:
The invention relates to compounds of formula (I) or the salts thereof, wherein Q is a (hetero)aromatic radical having up to 6 ring atoms, the ring of the heteroaromatic radical comprising 1, 2, 3 or 4 nitrogen atoms or 1 sulphur atom or 1 sulphur atom and 1 nitrogen atom as hetero-ring atoms, the radicals being substitutable as defined in claim 1, and A is an unsaturated divalent group of formula (A1), (A2), (A3), (A4) or (A5), wherein (R3)n, R4, R5, R6, R7, R8 and R9 are defined as in claim 1. Said compounds are suitable as herbicides and plant growth regulators. The compounds can be produced by the method according to claim 7.
摘要:
A method is disclosed for preparing hydrazides from hydrazine and an acyl chloride which comprises the steps of (a) preparing a stirred substantially uniform slurry comprising hydrazine and an inert solvent at low temperature; and (b) adding an acyl chloride continuously to said slurry. The method avoids or limits production of undesired bis-hydrazide by-products. The method is used to prepare 3-methyl-3-mercaptobutanoic acid hydrazide, a molecule used to link calicheamicin to a monoclonal antibody.
摘要:
N-Benzoyl arylsulfonamides having the formula (I) are BCL-Xl inhibitors and are useful for promoting apoptosis. Also disclosed are BCL-Xl inhibiting compositions and methods of promoting apoptosis in a mammal.
摘要:
The invention concerns novel arylalkyl compounds of general formula (I) in which Q stands for O, S, SO or SO2, R stands for hydrogen or optionally substituted alkyl, R stands for hydrogen or optionally substituted alkyl, Z stands for one of the groups: (a), (b), (c), and (Y)n, (X)m, R , R , R , R , R and R stand for hydrogen or given substituents. The invention also concerns processes for preparing these compounds, novel intermediate products, and the use of the arylalkyl compounds as herbicides.
摘要:
Compounds of Formula (I), and their agriculturally suitable salts, are disclosed which are useful as arthropodicides, wherein R?1, R2, R3, R4, R5¿, m and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula (I) and a method for controlling anthropods which involves contacting the arthropods or their environment with an effective amount of a compound of Formula (I).