公开(公告)号：US09282920B2

公开(公告)日：2016-03-15

申请号：US14011478

申请日：2013-08-27

Applicant: Google Inc.

Inventor： Harvey Ho ,  James Etzkorn ,  Huanfen Yao

IPC: H01L21/20 ,  A61B5/145 ,  A61B5/1486 ,  G02C7/04 ,  A61B5/00

CPC classification number: A61B5/14503 ,  A61B5/002 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/6821 ,  A61B2560/0214 ,  A61B2562/125 ,  G02C7/04

Abstract: A method may involve: forming a sacrificial layer on a working substrate; forming a first bio-compatible layer on the sacrificial layer such that the first bio-compatible layer adheres to the sacrificial layer; forming a conductive pattern on the first bio-compatible layer; mounting an electronic component to the conductive pattern; forming a second bio-compatible layer over the first bio-compatible layer, the electronic component, and the conductive pattern; and removing the sacrificial layer to release the bio-compatible device from the working substrate. The first bio-compatible layer defines a first side of a bio-compatible device. The second bio-compatible layer defines a second side of the bio-compatible device.

Abstract translation: 一种方法可以包括：在工作衬底上形成牺牲层; 在所述牺牲层上形成第一生物相容层，使得所述第一生物相容层附着于所述牺牲层; 在所述第一生物相容层上形成导电图案; 将电子部件安装到所述导电图案上; 在所述第一生物相容层，所述电子部件和所述导电图案上形成第二生物相容层; 以及去除所述牺牲层以从所述工作衬底释放所述生物相容性装置。 第一生物相容层限定生物相容装置的第一侧。 第二生物相容层限定生物相容装置的第二侧。

公开(公告)号：US09113829B2

公开(公告)日：2015-08-25

申请号：US13851290

申请日：2013-03-27

Applicant: Google Inc.

Inventor： James Etzkorn

IPC: A61B5/05 ,  A61B5/145 ,  G01N27/327 ,  C12Q1/00 ,  G02B1/04 ,  G02C7/04 ,  A61B5/1473 ,  A61B5/00 ,  H05K3/32 ,  H05K1/18 ,  A61B5/1477 ,  G02C7/08

CPC classification number: A61B5/14546 ,  A61B3/101 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/1473 ,  A61B5/1477 ,  A61B5/6813 ,  A61B5/6821 ,  A61B2560/0214 ,  A61B2562/12 ,  B29D11/00817 ,  C12Q1/006 ,  G01N27/3272 ,  G02B1/043 ,  G02C7/04 ,  G02C7/049 ,  G02C7/083 ,  H01L2224/04105 ,  H01L2924/18162 ,  H05K1/185 ,  H05K3/32 ,  H05K2201/10098 ,  H05K2201/10151 ,  H05K2203/1469 ,  Y10T29/49018 ,  Y10T29/4913 ,  Y10T29/49146 ,  Y10T29/49155 ,  Y10T29/49158 ,  Y10T29/49163

Abstract: A mountable device includes a bio-compatible structure embedded in a polymer that defines at least one mounting surface. The bio-compatible structure includes an electronic component having electrical contacts, sensor electrodes, and electrical interconnects between the sensor electrodes and the electrical contacts. The bio-compatible structure is fabricated such that it is fully encapsulated by a bio-compatible material, except for the sensor electrodes. In the fabrication, the electronic component is positioned on a first layer of bio-compatible material and a second layer of bio-compatible material is formed over the first layer of bio-compatible material and the electronic component. The electrical contacts are exposed by removing a portion of the second layer, a conductive pattern is formed to define the sensor electrodes and electrical interconnects, and a third layer of bio-compatible material is formed over the conductive pattern. The sensor electrodes are exposed by removing a portion of the third layer.

公开(公告)号：US20150173602A1

公开(公告)日：2015-06-25

申请号：US14139865

申请日：2013-12-23

Applicant: Google Inc.

Inventor： Daniel Patrick Barrows ,  Zenghe Liu ,  Jeffrey George Linherdt ,  James Etzkorn

IPC: A61B3/10 ,  A61B5/1477

CPC classification number: A61B3/101 ,  A61B5/002 ,  A61B5/14507 ,  A61B5/14532 ,  A61B5/1477 ,  A61B5/1486 ,  A61B5/6821 ,  A61B2560/0214 ,  A61B2562/12 ,  G02C7/04

Abstract: Molded electronic structures configured for use in body-mountable devices and methods for embedding molded electronic structures in a body-mountable device are described. An example method may include molding an electronic structure to have first curvature corresponding to a first radius of curvature. The electronic structure may include an antenna, a sensor, and an electronic device. The example method may also include adhering the molded electronic structure to a first polymer layer. The example method may additionally include forming a second polymer layer over the molded electronic structure adhered to the first polymer layer.

Abstract translation: 描述了构造成用于体内安装的装置中的模制电子结构和用于将模制的电子结构嵌入体内安装的装置中的方法。 示例性方法可以包括将电子结构模制成具有对应于第一曲率半径的第一曲率。 电子结构可以包括天线，传感器和电子设备。 该示例性方法还可以包括将模制的电子结构粘附到第一聚合物层。 该示例性方法可以另外包括在粘附到第一聚合物层上的模制电子结构上形成第二聚合物层。

公开(公告)号：US08960899B2

公开(公告)日：2015-02-24

申请号：US13627574

申请日：2012-09-26

Applicant: Google Inc.

Inventor： James Etzkorn

IPC: G02C7/02 ,  H01L23/48 ,  H01L21/56 ,  G02C7/04 ,  H01L23/00

CPC classification number: G02C11/10 ,  A61B5/6821 ,  A61B2562/12 ,  B29D11/00048 ,  B29D11/00807 ,  G02C7/04 ,  G02C7/049 ,  H01L21/56 ,  H01L21/563 ,  H01L21/768 ,  H01L23/3107 ,  H01L23/3121 ,  H01L23/48 ,  H01L23/528 ,  H01L24/03 ,  H01L24/05 ,  H01L24/09 ,  H01L24/11 ,  H01L24/13 ,  H01L24/16 ,  H01L24/29 ,  H01L24/32 ,  H01L24/73 ,  H01L24/742 ,  H01L24/81 ,  H01L24/83 ,  H01L24/89 ,  H01L24/97 ,  H01L2224/02375 ,  H01L2224/0401 ,  H01L2224/05548 ,  H01L2224/05553 ,  H01L2224/05554 ,  H01L2224/08225 ,  H01L2224/11312 ,  H01L2224/13109 ,  H01L2224/16225 ,  H01L2224/16227 ,  H01L2224/291 ,  H01L2224/2919 ,  H01L2224/2929 ,  H01L2224/293 ,  H01L2224/32225 ,  H01L2224/73204 ,  H01L2224/8012 ,  H01L2224/8085 ,  H01L2224/81191 ,  H01L2224/81192 ,  H01L2224/81193 ,  H01L2224/81203 ,  H01L2224/81204 ,  H01L2224/81815 ,  H01L2224/81903 ,  H01L2224/83191 ,  H01L2224/83192 ,  H01L2224/83203 ,  H01L2224/83851 ,  H01L2224/83855 ,  H01L2224/9211 ,  H01L2224/92125 ,  H01L2924/00014 ,  H01L2924/10161 ,  H01L2924/10162 ,  H01L2924/10253 ,  H01L2924/12041 ,  H01L2924/14 ,  H01L2924/2064 ,  H01L2924/20641 ,  H01L2924/20642 ,  H01L2924/20643 ,  H01L2924/20644 ,  H01L2924/20645 ,  H01L2924/20646 ,  H01L2924/20647 ,  H01L2924/20648 ,  H01L2924/20649 ,  H01L2924/2065 ,  H01L2924/00 ,  H01L2224/83104 ,  H01L2224/05599 ,  H01L2924/013 ,  H01L2924/0105 ,  H01L2924/01083 ,  H01L2924/00013 ,  H01L2924/20105 ,  H01L2924/00012 ,  H01L2924/0665

Abstract: A contact lens having a thin silicon chip integrated therein is provided along with methods for assembling the silicon chip within the contact lens. In an aspect, a method includes creating a plurality of lens contact pads on a lens substrate and creating a plurality of chip contact pads on a chip. The method further involves applying assembly bonding material to the each of the plurality of lens contact pads or chip contact pads, aligning the plurality of lens contact pads with the plurality of chip contact pads, bonding the chip to the lens substrate via the assembly bonding material using flip chip bonding, and forming a contact lens with the lens substrate.

公开(公告)号：US20140371559A1

公开(公告)日：2014-12-18

申请号：US14035352

申请日：2013-09-24

Applicant: Google Inc.

Inventor： James Etzkorn ,  Stephen O'Driscoll

IPC: A61B5/00 ,  A61B5/1486 ,  A61B5/145

CPC classification number: A61B5/14532 ,  A61B5/002 ,  A61B5/1486 ,  A61B5/682 ,  A61B5/6821 ,  A61B2562/12 ,  G02C7/04 ,  Y10T156/1028

Abstract: Body-mountable devices and methods for embedding a structure in a body-mountable device are described. A body-mountable device includes a transparent polymer and a structure embedded in the transparent polymer. The transparent polymer defines a posterior side and an anterior side of the body-mountable device. The structure has an outer diameter and an inner diameter and includes a sensor configured to detect an analyte and an antenna. The antenna includes a plurality of conductive loops spaced apart from each other between the outer diameter and the inner diameter.

Abstract translation: 描述了用于将结构嵌入体内安装的装置中的车身安装的装置和方法。 体内安装装置包括透明聚合物和嵌入透明聚合物中的结构。 透明聚合物限定身体安装装置的后侧和前侧。 该结构具有外径和内径，并且包括被配置为检测分析物和天线的传感器。 天线包括在外径和内径之间彼此间隔开的多个导电回路。

公开(公告)号：US08886275B2

公开(公告)日：2014-11-11

申请号：US14031862

申请日：2013-09-19

Applicant: Google Inc.

Inventor： James Etzkorn ,  Babak Amirparviz

IPC: A61B5/05 ,  G01N33/50 ,  C12N9/00 ,  G01N27/26 ,  A61B5/1473 ,  A61B5/145 ,  A61B5/00 ,  A61B5/1486 ,  G01N27/327

CPC classification number: A61B5/6821 ,  A61B5/0002 ,  A61B5/0004 ,  A61B5/14507 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/14865 ,  A61B5/6867 ,  G01N27/3271 ,  G02C7/04 ,  H01L21/568 ,  H01L23/3107 ,  H01L2224/81001 ,  Y10T29/49826

Abstract: An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor includes a working electrode and a reference electrode that reacts with an analyte to generate a sensor measurement related to a concentration of the analyte in a fluid to which the eye-mountable device is exposed. An example assembly process includes: forming a sacrificial layer on a working substrate; forming a first layer of a bio-compatible material on the sacrificial layer; providing an electronics module on the first layer of the bio-compatible material, forming a second layer of the bio-compatible material to cover the electronics module; and annealing the first and second layers of the bio-compatible material together to form an encapsulated structure having the electronics module fully encapsulated by the bio-compatible material.

Abstract translation: 一种可眼睛安装的装置包括嵌入聚合物材料中的电化学传感器，其被配置用于安装到眼睛的表面。 电化学传感器包括工作电极和与分析物反应的参比电极，以产生与可眼睛安装的装置暴露的流体中的分析物的浓度相关的传感器测量。 示例性组装过程包括：在工作衬底上形成牺牲层; 在所述牺牲层上形成生物相容性材料的第一层; 在所述生物相容材料的第一层上提供电子模块，形成所述生物相容材料的第二层以覆盖所述电子模块; 以及将所述生物相容性材料的所述第一和第二层退火在一起以形成具有由所述生物相容性材料完全包封的所述电子模块的封装结构。

公开(公告)号：US20140329303A1

公开(公告)日：2014-11-06

申请号：US14338429

申请日：2014-07-23

Applicant: Google Inc.

Inventor： Zenghe Liu ,  James Etzkorn

IPC: G01N33/52 ,  G01N33/53 ,  G01N33/543 ,  G01N21/64

CPC classification number: G01N33/528 ,  B01J2219/00612 ,  B01J2219/00621 ,  G01N21/6486 ,  G01N21/75 ,  G01N33/5304 ,  G01N33/54366 ,  G01N33/54386 ,  G01N33/62 ,  G01N33/66 ,  G01N33/92 ,  G01N33/98 ,  G01N2333/46 ,  Y10T436/144444

Abstract: Contact lens testing apparatuses and method for testing contact lenses for analytes are presented. In an aspect, a device is provided that includes a housing configured to hold one or more contact lenses, and a testing compartment provided within the housing and comprising a reagent, the reagent configured to facilitate a chemical reaction in response to the existence of a predetermined biomarker disposed on or within a contact lens placed in the testing compartment, wherein the chemical reaction produces a known result related to state information of an individual from which the biomarker was generated.

Abstract translation: 介绍了用于测试分析物的隐形眼镜的隐形眼镜测试仪器和方法。 一方面，提供了一种装置，其包括构造成保持一个或多个隐形眼镜的壳体，以及设置在壳体内并包括试剂的测试室，所述试剂被配置为响应于存在预定的 放置在测试室中的隐形眼镜上或其内的生物标志物，其中化学反应产生与生成生物标志物的个体的状态信息相关的已知结果。

公开(公告)号：US08880139B1

公开(公告)日：2014-11-04

申请号：US14034323

申请日：2013-09-23

Applicant: Google Inc.

Inventor： James Etzkorn ,  Zenghe Liu

IPC: A61B5/05 ,  G01N33/50 ,  G01N27/26 ,  C12N9/00 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/1477 ,  A61B5/145 ,  G01N27/327

CPC classification number: A61B5/1486 ,  A61B3/101 ,  A61B5/0002 ,  A61B5/0004 ,  A61B5/002 ,  A61B5/14507 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1477 ,  A61B5/6821 ,  A61B5/7264 ,  A61B2560/0214 ,  G01N27/30 ,  G01N27/3271 ,  G01N27/4166 ,  G02C7/04

Abstract: An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor includes a working electrode, a reference electrode, and a reagent that selectively reacts with an analyte to generate a sensor measurement related to a concentration of the analyte in a fluid to which the eye-mountable device is exposed. The working electrode can have a first side edge and a second side edge. The reference electrode can be situated such that at least a portion of the first and second side edges of the working electrode are adjacent respective sections of the reference electrode.

Abstract translation: 一种可眼睛安装的装置包括嵌入聚合物材料中的电化学传感器，其被配置用于安装到眼睛的表面。 电化学传感器包括工作电极，参比电极和选择性地与分析物反应以产生与可眼睛安装的装置暴露于的流体中的分析物的浓度相关的传感器测量的试剂。 工作电极可以具有第一侧边缘和第二侧边缘。 参考电极可以被定位成使得工作电极的第一和第二侧边缘的至少一部分与参考电极的相应部分相邻。

公开(公告)号：US08874182B2

公开(公告)日：2014-10-28

申请号：US13741725

申请日：2013-01-15

Applicant: Google Inc.

Inventor： James Etzkorn ,  Babak Amirparviz

IPC: A61B5/05 ,  A61B5/00 ,  A61B5/1486 ,  A61B5/145 ,  G01N27/327

CPC classification number: A61B5/6821 ,  A61B5/0002 ,  A61B5/0004 ,  A61B5/14507 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/14865 ,  A61B5/6867 ,  G01N27/3271 ,  G02C7/04 ,  H01L21/568 ,  H01L23/3107 ,  H01L2224/81001 ,  Y10T29/49826

Abstract: An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor includes a working electrode and a reference electrode that reacts with an analyte to generate a sensor measurement related to a concentration of the analyte in a fluid to which the eye-mountable device is exposed. An example assembly process includes: forming a sacrificial layer on a working substrate; forming a first layer of a bio-compatible material on the sacrificial layer; providing an electronics module on the first layer of the bio-compatible material, forming a second layer of the bio-compatible material to cover the electronics module; and annealing the first and second layers of the bio-compatible material together to form an encapsulated structure having the electronics module fully encapsulated by the bio-compatible material.

公开(公告)号：US08821811B2

公开(公告)日：2014-09-02

申请号：US13627727

申请日：2012-09-26

Applicant: Google Inc.

Inventor： Zenghe Liu ,  James Etzkorn

IPC: G01N21/75 ,  C12M1/34 ,  C12M3/00

CPC classification number: G01N33/528 ,  B01J2219/00612 ,  B01J2219/00621 ,  G01N21/6486 ,  G01N21/75 ,  G01N33/5304 ,  G01N33/54366 ,  G01N33/54386 ,  G01N33/62 ,  G01N33/66 ,  G01N33/92 ,  G01N33/98 ,  G01N2333/46 ,  Y10T436/144444

Abstract: Contact lens testing apparatuses and method for testing contact lenses for analytes are presented. In an aspect, a device is provided that includes a housing configured to hold one or more contact lenses, and a testing compartment provided within the housing and comprising a reagent, the reagent configured to facilitate a chemical reaction in response to the existence of a predetermined biomarker disposed on or within a contact lens placed in the testing compartment, wherein the chemical reaction produces a known result related to state information of an individual from which the biomarker was generated.