公开(公告)号：US08187838B2

公开(公告)日：2012-05-29

申请号：US12789167

申请日：2010-05-27

申请人： Hiroshi Tsukamoto ,  Toshiki Mine ,  Yoshimitsu Takakura ,  Takeshi Yamamoto

发明人： Hiroshi Tsukamoto ,  Toshiki Mine ,  Yoshimitsu Takakura ,  Takeshi Yamamoto

IPC分类号： C12P21/02

CPC分类号： C12N9/1081 ,  C07H21/04

摘要： The present invention provides a novel β-galactoside-α2,6-sialyltransferase having high productivity and/or high activity, and a nucleic acid encoding the sialyltransferase. The present invention also provides a microorganism producing the sialyltransferase. The present invention further provides a vector carrying a nucleic acid encoding the sialyltransferase, and a host cell transformed with the vector, as well as a method for producing a recombinant β-galactoside-α2,6-sialyltransferase.

摘要翻译： 本发明提供了具有高生产力和/或高活性的新颖的β-半乳糖苷-α2,6-唾液酸转移酶和编码唾液酸转移酶的核酸。 本发明还提供了产生唾液酸转移酶的微生物。 本发明还提供了携带编码唾液酸转移酶的核酸的载体和用载体转化的宿主细胞，以及用于产生重组和半乳糖苷-α2,6-唾液酸转移酶的方法。

公开(公告)号：US08063489B2

公开(公告)日：2011-11-22

申请号：US12628869

申请日：2009-12-01

申请人： Hiromi Shigihara ,  Hiroshi Tsukamoto ,  Akira Yajima

发明人： Hiromi Shigihara ,  Hiroshi Tsukamoto ,  Akira Yajima

IPC分类号： H01L23/52

CPC分类号： H01L24/05 ,  H01L21/565 ,  H01L22/32 ,  H01L23/485 ,  H01L23/49816 ,  H01L24/06 ,  H01L24/12 ,  H01L24/16 ,  H01L24/45 ,  H01L24/46 ,  H01L24/48 ,  H01L24/49 ,  H01L24/73 ,  H01L24/78 ,  H01L24/81 ,  H01L24/85 ,  H01L25/0657 ,  H01L2224/02166 ,  H01L2224/02205 ,  H01L2224/0347 ,  H01L2224/0401 ,  H01L2224/04042 ,  H01L2224/05027 ,  H01L2224/05082 ,  H01L2224/05083 ,  H01L2224/05084 ,  H01L2224/05124 ,  H01L2224/05144 ,  H01L2224/05147 ,  H01L2224/05155 ,  H01L2224/05157 ,  H01L2224/05164 ,  H01L2224/05166 ,  H01L2224/05169 ,  H01L2224/05173 ,  H01L2224/05181 ,  H01L2224/05184 ,  H01L2224/05553 ,  H01L2224/05554 ,  H01L2224/05558 ,  H01L2224/05564 ,  H01L2224/05568 ,  H01L2224/05572 ,  H01L2224/05583 ,  H01L2224/05624 ,  H01L2224/05644 ,  H01L2224/05647 ,  H01L2224/05655 ,  H01L2224/05664 ,  H01L2224/05666 ,  H01L2224/0568 ,  H01L2224/06183 ,  H01L2224/1134 ,  H01L2224/13099 ,  H01L2224/13144 ,  H01L2224/13147 ,  H01L2224/16225 ,  H01L2224/2919 ,  H01L2224/29198 ,  H01L2224/32145 ,  H01L2224/32225 ,  H01L2224/32245 ,  H01L2224/4502 ,  H01L2224/45124 ,  H01L2224/45144 ,  H01L2224/45147 ,  H01L2224/45164 ,  H01L2224/46 ,  H01L2224/4807 ,  H01L2224/48095 ,  H01L2224/48145 ,  H01L2224/48158 ,  H01L2224/48247 ,  H01L2224/48453 ,  H01L2224/48465 ,  H01L2224/48471 ,  H01L2224/48507 ,  H01L2224/48624 ,  H01L2224/48639 ,  H01L2224/48644 ,  H01L2224/48647 ,  H01L2224/48655 ,  H01L2224/48664 ,  H01L2224/4868 ,  H01L2224/48724 ,  H01L2224/48739 ,  H01L2224/48744 ,  H01L2224/48747 ,  H01L2224/48755 ,  H01L2224/48764 ,  H01L2224/4878 ,  H01L2224/48824 ,  H01L2224/48839 ,  H01L2224/48844 ,  H01L2224/48847 ,  H01L2224/48855 ,  H01L2224/48864 ,  H01L2224/4888 ,  H01L2224/49171 ,  H01L2224/49175 ,  H01L2224/73204 ,  H01L2224/73265 ,  H01L2224/78301 ,  H01L2224/81193 ,  H01L2224/81801 ,  H01L2224/83101 ,  H01L2224/85181 ,  H01L2224/85186 ,  H01L2224/85205 ,  H01L2224/85207 ,  H01L2224/85439 ,  H01L2224/85444 ,  H01L2224/85464 ,  H01L2225/0651 ,  H01L2225/06517 ,  H01L2924/00011 ,  H01L2924/01004 ,  H01L2924/01005 ,  H01L2924/01006 ,  H01L2924/01011 ,  H01L2924/01013 ,  H01L2924/01014 ,  H01L2924/01015 ,  H01L2924/01018 ,  H01L2924/01019 ,  H01L2924/01022 ,  H01L2924/01024 ,  H01L2924/01025 ,  H01L2924/01028 ,  H01L2924/01029 ,  H01L2924/01033 ,  H01L2924/01042 ,  H01L2924/01045 ,  H01L2924/01046 ,  H01L2924/01047 ,  H01L2924/0105 ,  H01L2924/01061 ,  H01L2924/01065 ,  H01L2924/01073 ,  H01L2924/01074 ,  H01L2924/01075 ,  H01L2924/01078 ,  H01L2924/01079 ,  H01L2924/01082 ,  H01L2924/01327 ,  H01L2924/014 ,  H01L2924/04941 ,  H01L2924/04953 ,  H01L2924/05042 ,  H01L2924/078 ,  H01L2924/09701 ,  H01L2924/10253 ,  H01L2924/12042 ,  H01L2924/1306 ,  H01L2924/13091 ,  H01L2924/14 ,  H01L2924/15311 ,  H01L2924/15787 ,  H01L2924/15788 ,  H01L2924/181 ,  H01L2924/19041 ,  H01L2924/19043 ,  H01L2924/3511 ,  H01L2924/00014 ,  H01L2924/01039 ,  H01L2924/0665 ,  H01L2224/48227 ,  H01L2924/00 ,  H01L2924/00012 ,  H01L2924/0002 ,  H01L2924/00015

摘要： In semiconductor integrated circuit devices for vehicle use or the like, in general, an aluminum pad on a semiconductor chip and an external device are coupled to each other by wire bonding or the like using a gold wire and the like for the convenience of mounting. Such a semiconductor integrated circuit device, however, causes a connection failure due to the interaction between aluminum and gold in use for a long time at a relatively high temperature (about 150 degrees C.). The invention of the present application provides a semiconductor integrated circuit device (semiconductor device or electron circuit device) which includes a semiconductor chip as a part of the device, an electrolytic gold plated surface film (gold-based metal plated film) provided over an aluminum-based bonding pad on a semiconductor chip via a barrier metal film, and a gold bonding wire (gold-based bonding wire) for interconnection between the plated surface film and an external lead provided over a wiring board or the like (wiring substrate).

摘要翻译： 在用于车辆用途的半导体集成电路装置等中，为了便于安装，通常使用金线等通过引线接合等将半导体芯片上的铝焊盘和外部装置彼此耦合。 然而，这样的半导体集成电路器件在相对较高的温度（约150℃）下长时间使用铝和金之间的相互作用导致连接故障。 本申请的发明提供了一种半导体集成电路器件（半导体器件或电子电路器件），其包括作为器件的一部分的半导体芯片，设置在铝上的电解镀金表面膜（金基金属镀膜） 通过阻挡金属膜在半导体芯片上的金焊接焊盘和用于在电镀表面膜和设置在布线基板等上的外部引线之间互连的金键合线（金基接合线）。

公开(公告)号：US20100158720A1

公开(公告)日：2010-06-24

申请号：US11997126

申请日：2006-07-10

申请人： Koji Miyazaki ,  Seiichi Tanaka ,  Hiroyuki Shimooka ,  Hiroshi Tsukamoto

发明人： Koji Miyazaki ,  Seiichi Tanaka ,  Hiroyuki Shimooka ,  Hiroshi Tsukamoto

IPC分类号： F04B43/04 ,  B81B3/00 ,  F04B43/02

CPC分类号： F04B43/046 ,  F04B53/1077

摘要： A valveless micropump for transforming a pressure variation of fluid in a volume variation chamber (8) into an oscillatory flow of fluid (10) by means of a piezoelectric element (7), making the fluid (10) to flow smoothly in channels (5, 6). A channel (2) is formed as an asymmetric diffuser-shaped channel (12) having a narrow channel (5) on the diffuser inlet (3) side and a wide channel (6) on the diffuser outlet (4) side, and the volume variation chamber (8) provided with the piezoelectric element (7) is communicated with the narrow channel (5). Vibration generated by applying a voltage to the piezoelectric element (7) causes a pressure variation of the fluid in the volume variation chamber (8) to generate a nozzle flow. The fluid (10) is made to flow smoothly from the wide channel (6) to the narrow channel (5) by the nozzle flow.

摘要翻译： 一种无阀微型泵，用于通过压电元件（7）将体积变化室（8）中的流体的压力变化转换成流体（10）的振荡流，使流体（10）在通道（5） ，6）。 通道（2）形成为在扩散器入口（3）侧具有窄通道（5）和扩散器出口（4）侧上的宽通道（6）的不对称扩散器形状的通道（12），并且 设置有压电元件（7）的体积变化室（8）与窄通道（5）连通。 通过向压电元件（7）施加电压产生的振动导致体积变化室（8）中的流体的压力变化产生喷嘴流。 流体（10）通过喷嘴流动从宽通道（6）平滑地流动到窄通道（5）。

公开(公告)号：US20100133688A1

公开(公告)日：2010-06-03

申请号：US12628869

申请日：2009-12-01

申请人： Hiromi Shigihara ,  Hiroshi Tsukamoto ,  Akira Yajima

发明人： Hiromi Shigihara ,  Hiroshi Tsukamoto ,  Akira Yajima

IPC分类号： H01L23/488

CPC分类号： H01L24/05 ,  H01L21/565 ,  H01L22/32 ,  H01L23/485 ,  H01L23/49816 ,  H01L24/06 ,  H01L24/12 ,  H01L24/16 ,  H01L24/45 ,  H01L24/46 ,  H01L24/48 ,  H01L24/49 ,  H01L24/73 ,  H01L24/78 ,  H01L24/81 ,  H01L24/85 ,  H01L25/0657 ,  H01L2224/02166 ,  H01L2224/02205 ,  H01L2224/0347 ,  H01L2224/0401 ,  H01L2224/04042 ,  H01L2224/05027 ,  H01L2224/05082 ,  H01L2224/05083 ,  H01L2224/05084 ,  H01L2224/05124 ,  H01L2224/05144 ,  H01L2224/05147 ,  H01L2224/05155 ,  H01L2224/05157 ,  H01L2224/05164 ,  H01L2224/05166 ,  H01L2224/05169 ,  H01L2224/05173 ,  H01L2224/05181 ,  H01L2224/05184 ,  H01L2224/05553 ,  H01L2224/05554 ,  H01L2224/05558 ,  H01L2224/05564 ,  H01L2224/05568 ,  H01L2224/05572 ,  H01L2224/05583 ,  H01L2224/05624 ,  H01L2224/05644 ,  H01L2224/05647 ,  H01L2224/05655 ,  H01L2224/05664 ,  H01L2224/05666 ,  H01L2224/0568 ,  H01L2224/06183 ,  H01L2224/1134 ,  H01L2224/13099 ,  H01L2224/13144 ,  H01L2224/13147 ,  H01L2224/16225 ,  H01L2224/2919 ,  H01L2224/29198 ,  H01L2224/32145 ,  H01L2224/32225 ,  H01L2224/32245 ,  H01L2224/4502 ,  H01L2224/45124 ,  H01L2224/45144 ,  H01L2224/45147 ,  H01L2224/45164 ,  H01L2224/46 ,  H01L2224/4807 ,  H01L2224/48095 ,  H01L2224/48145 ,  H01L2224/48158 ,  H01L2224/48247 ,  H01L2224/48453 ,  H01L2224/48465 ,  H01L2224/48471 ,  H01L2224/48507 ,  H01L2224/48624 ,  H01L2224/48639 ,  H01L2224/48644 ,  H01L2224/48647 ,  H01L2224/48655 ,  H01L2224/48664 ,  H01L2224/4868 ,  H01L2224/48724 ,  H01L2224/48739 ,  H01L2224/48744 ,  H01L2224/48747 ,  H01L2224/48755 ,  H01L2224/48764 ,  H01L2224/4878 ,  H01L2224/48824 ,  H01L2224/48839 ,  H01L2224/48844 ,  H01L2224/48847 ,  H01L2224/48855 ,  H01L2224/48864 ,  H01L2224/4888 ,  H01L2224/49171 ,  H01L2224/49175 ,  H01L2224/73204 ,  H01L2224/73265 ,  H01L2224/78301 ,  H01L2224/81193 ,  H01L2224/81801 ,  H01L2224/83101 ,  H01L2224/85181 ,  H01L2224/85186 ,  H01L2224/85205 ,  H01L2224/85207 ,  H01L2224/85439 ,  H01L2224/85444 ,  H01L2224/85464 ,  H01L2225/0651 ,  H01L2225/06517 ,  H01L2924/00011 ,  H01L2924/01004 ,  H01L2924/01005 ,  H01L2924/01006 ,  H01L2924/01011 ,  H01L2924/01013 ,  H01L2924/01014 ,  H01L2924/01015 ,  H01L2924/01018 ,  H01L2924/01019 ,  H01L2924/01022 ,  H01L2924/01024 ,  H01L2924/01025 ,  H01L2924/01028 ,  H01L2924/01029 ,  H01L2924/01033 ,  H01L2924/01042 ,  H01L2924/01045 ,  H01L2924/01046 ,  H01L2924/01047 ,  H01L2924/0105 ,  H01L2924/01061 ,  H01L2924/01065 ,  H01L2924/01073 ,  H01L2924/01074 ,  H01L2924/01075 ,  H01L2924/01078 ,  H01L2924/01079 ,  H01L2924/01082 ,  H01L2924/01327 ,  H01L2924/014 ,  H01L2924/04941 ,  H01L2924/04953 ,  H01L2924/05042 ,  H01L2924/078 ,  H01L2924/09701 ,  H01L2924/10253 ,  H01L2924/12042 ,  H01L2924/1306 ,  H01L2924/13091 ,  H01L2924/14 ,  H01L2924/15311 ,  H01L2924/15787 ,  H01L2924/15788 ,  H01L2924/181 ,  H01L2924/19041 ,  H01L2924/19043 ,  H01L2924/3511 ,  H01L2924/00014 ,  H01L2924/01039 ,  H01L2924/0665 ,  H01L2224/48227 ,  H01L2924/00 ,  H01L2924/00012 ,  H01L2924/0002 ,  H01L2924/00015

摘要： In semiconductor integrated circuit devices for vehicle use or the like, in general, an aluminum pad on a semiconductor chip and an external device are coupled to each other by wire bonding or the like using a gold wire and the like for the convenience of mounting. Such a semiconductor integrated circuit device, however, causes a connection failure due to the interaction between aluminum and gold in use for a long time at a relatively high temperature (about 150 degrees C.). The invention of the present application provides a semiconductor integrated circuit device (semiconductor device or electron circuit device) which includes a semiconductor chip as a part of the device, an electrolytic gold plated surface film (gold-based metal plated film) provided over an aluminum-based bonding pad on a semiconductor chip via a barrier metal film, and a gold bonding wire (gold-based bonding wire) for interconnection between the plated surface film and an external lead provided over a wiring board or the like (wiring substrate).

摘要翻译： 在用于车辆用途的半导体集成电路装置等中，为了便于安装，通常使用金线等通过引线接合等将半导体芯片上的铝焊盘和外部装置彼此耦合。 然而，这样的半导体集成电路器件在相对较高的温度（约150℃）下长时间使用铝和金之间的相互作用导致连接故障。 本申请的发明提供了一种半导体集成电路器件（半导体器件或电子电路器件），其包括作为器件的一部分的半导体芯片，设置在铝上的电解镀金表面膜（金基金属镀膜） 通过阻挡金属膜在半导体芯片上的金焊接焊盘和用于在电镀表面膜和设置在布线基板等上的外部引线之间互连的金键合线（金基接合线）。

公开(公告)号：US20090224602A1

公开(公告)日：2009-09-10

申请号：US12379831

申请日：2009-03-03

申请人： Hiroshi Tsukamoto

发明人： Hiroshi Tsukamoto

IPC分类号： H02J1/00 ,  G05F1/00

CPC分类号： H02M3/156 ,  H02M2001/008 ,  Y10T307/406

摘要： There is provided a DC-DC converter control circuit, wherein a reference feedback signal related to a supply voltage to a load is compared to a reference oscillation signal to generate a result of comparison. The result of comparison is used as a switching control signal to control the supply voltage to the load. The result of comparison is frequency divided to generate a frequency divided signal; and the switching control signal is generated in response to the frequency divided signal.

摘要翻译： 提供了一种DC-DC转换器控制电路，其中将与负载的电源电压相关的参考反馈信号与参考振荡信号进行比较以产生比较结果。 比较结果被用作开关控制信号以控制负载的电源电压。 比较结果被分频，以产生分频信号; 并且响应于分频信号产生开关控制信号。

公开(公告)号：US07552663B2

公开(公告)日：2009-06-30

申请号：US11271956

申请日：2005-11-14

申请人： Fumikage Yamanaka ,  Takahiko Midori ,  Satoru Masuda ,  Hiroshi Tsukamoto

发明人： Fumikage Yamanaka ,  Takahiko Midori ,  Satoru Masuda ,  Hiroshi Tsukamoto

IPC分类号： G05G1/04

CPC分类号： F16C1/12 ,  B60T7/10 ,  B60T11/046 ,  Y10T74/2042 ,  Y10T74/20612

摘要： A parking brake apparatus for activating a brake unit includes a base member; an operating lever supported on the base member for generating an operating force when the operating lever is operated so that the operating force is transmitted to the brake unit through a brake cable; an inputting member to be rotated with the operating lever; an intermediating member disposed separately from the inputting member for interconnecting the inputting member and the brake cable; and a connection member for connecting the intermediating member and the inputting member. Accordingly, the intermediating member transmits the operating force to the brake cable from the connection member.

摘要翻译： 一种用于启动制动单元的驻车制动装置包括基座构件; 支撑在所述基座构件上的操作杆，用于当所述操作杆被操作时产生操作力，使得所述操作力通过制动缆索传递到所述制动单元; 与操作杆一起旋转的输入构件; 与所述输入构件分离设置的用于互连所述输入构件和所述制动电缆的中间构件; 以及用于连接中间构件和输入构件的连接构件。 因此，中间构件将连接构件的操作力传递到制动电缆。

公开(公告)号：US20090087894A1

公开(公告)日：2009-04-02

申请号：US11665568

申请日：2005-09-30

申请人： Hiroshi Tsukamoto ,  Takeshi Yamamoto ,  Yoshimitsu Takakura

发明人： Hiroshi Tsukamoto ,  Takeshi Yamamoto ,  Yoshimitsu Takakura

IPC分类号： C12N9/10

CPC分类号： C12N9/1048

摘要： The present invention provides an inexpensive and simple method which allows efficient glycosylation with glycosyltransferases derived from microorganisms of the Vibrionaceae family when compared to conventional enzymatic reaction systems.According to the method of the present invention, glycosyltransferases derived from microorganisms of the Vibrionaceae, such as β-galactoside-α2,6-sialyltransferase derived from Photobacterium damselae, β-galactoside-α2,3-sialyltransferase derived from Photobacterium phosphoreum and β-galactoside-α2,3-sialyltransferase derived from Vibrio sp., enhance their enzymatic activity when an appropriate amount of NaCl is added to their enzyme reaction systems.

摘要翻译： 本发明提供了一种便宜且简单的方法，当与常规的酶反应体系相比时，可以使用衍生自Vibrionaceae家族的微生物的糖基转移酶进行有效的糖基化。 根据本发明的方法，衍生自Vibrionaceae的微生物的糖基转移酶，例如源自斑马鱼的β-半乳糖苷-α2,6-唾液酸转移酶，衍生自Photobacterium磷光体的β-半乳糖苷-α2,3-唾液酸转移酶和β-半乳糖苷 来自弧菌属的α2,3唾液酸转移酶，当将适量的NaCl加入其酶反应体系时，增强其酶活性。

公开(公告)号：US06313069B1

公开(公告)日：2001-11-06

申请号：US08875079

申请日：1997-07-17

申请人： Hiroshi Tsukamoto ,  Michiyo Takabayashi ,  Tadaharu Hieda ,  Masatoshi Gohbara

发明人： Hiroshi Tsukamoto ,  Michiyo Takabayashi ,  Tadaharu Hieda ,  Masatoshi Gohbara

IPC分类号： A01N6304

CPC分类号： C12R1/645 ,  A01N63/04 ,  C12N1/14

摘要： The invention relates to a strain belonging to Exserohilum monoceras which shows the esterase zymogram pattern shown in FIG. 1, a weed-controlling agent containing the same, and a weed-controlling method using the same. The invention provides a novel strain belonging to Exserohilum monoceras excellent in herbicidal effects as well as in spore productivity.

摘要翻译： 本发明涉及属于Exserohilum monoceras的菌株，其显示了图3所示的酯酶酶谱图。 1，含有该杂草的除草剂，以及使用其的除草控制方法。 本发明提供了一种属于除草效果以及孢子生产力优异的Exserohilum monoceras的新菌株。

公开(公告)号：US5843428A

公开(公告)日：1998-12-01

申请号：US507480

申请日：1995-08-28

申请人： Hiroshi Tsukamoto ,  Yoko Fukuhara ,  Fumiki Tsutsumi ,  Masao Yamada ,  Tsuneo Namai

发明人： Hiroshi Tsukamoto ,  Yoko Fukuhara ,  Fumiki Tsutsumi ,  Masao Yamada ,  Tsuneo Namai

IPC分类号： A01N63/04 ,  A01N63/00

CPC分类号： A01N63/04 ,  Y10S435/911

摘要： The present invention relates to a disease-controlling agent for useful gramineous plants such as rices, corns, wheats, barleys, ryes and oats, comprising as an active ingredient a microorganism belonging to the genus Exserohilum and having an ability to control diseases of useful gramineous plants, as well as a disease control method for gramineous plants comprising applying said agent to useful gramineous plants including rices, corns, wheats, barleys, ryes and oats.

摘要翻译： PCT No.PCT / JP94 / 02286 Sec。 371日期：1995年8月28日 102（e）日期1995年8月28日PCT 1994年12月28日PCT公布。 WO95 / 17820PC出版物 日期：1995年7月6日本发明涉及麸，玉米，小麦，大麦，磨粒和燕麦等有用的禾本科植物的疾病控制剂，其包含作为活性成分的属于Exserohilum属的微生物， 控制有用的禾本科植物的疾病，以及用于禾本科植物的疾病控制方法，包括将所述试剂施用于有用的禾本科植物，包括ices ices，玉米，小麦，大麦，yes yes和燕麦。