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    Wicking-based reagent-solution draining in an automated system
    71.
    发明授权
    Wicking-based reagent-solution draining in an automated system 有权
    基于芯片的试剂溶液在自动化系统中排水

    公开(公告)号：US08580201B2

    公开(公告)日：2013-11-12

    申请号：US12932337

    申请日：2011-02-22

    申请人： Hsing-Yeh Parker ,  John C. Tabone ,  John Mulligan

    发明人： Hsing-Yeh Parker ,  John C. Tabone ,  John Mulligan

    IPC分类号： B01J19/00 ,  B01J8/00 ,  B01J8/04 ,  C12Q1/68 ,  G01N31/00 ,  G01N33/00 ,  G01N31/22 ,  G01N33/52 ,  B01L3/00 ,  B01L99/00 ,  B01L3/02 ,  F04D19/00 ,  B01D21/00

    CPC分类号： B01J19/0046 ,  B01J2219/00286 ,  B01J2219/00315 ,  B01J2219/0036 ,  B01J2219/00414 ,  B01J2219/00423 ,  B01J2219/00722

    摘要： Embodiments of the present invention include processing steps and subsystems, within automated-biopolymer-synthesis systems and within other automated systems for organic-chemistry-based processing, for removing reagent solutions and solvents from reaction chambers following various synthetic reaction steps and washing steps undertaken during biopolymer synthesis. Embodiments of the present invention employ any of various different types of liquid-absorbing materials to wick, or remove by capillary action, liquids from reaction chambers. Wicking-based methods and subcomponents of the present invention remove significantly greater fractions of solutions from reaction chambers than conventional methods and subsystems and, in addition, are mechanically simpler and produce fewer deleterious side effects than currently used methods and subsystems.

    摘要翻译： 本发明的实施方案包括在自动生物聚合物 - 合成系统内和在用于基于有机化学的处理的其他自动化系统内的处理步骤和子系统，用于在各种合成反应步骤之后从反应室中除去试剂溶液和溶剂，并在 生物聚合物合成。 本发明的实施例使用各种不同类型的液体吸收材料中的任何一种来吸收或者通过毛细管作用从反应室中除去液体。 与常规方法和子系统相比，本发明的基于芯吸的方法和子部件从常规方法和子系统中除去反应室的溶液的显着更多的部分，此外，与目前使用的方法和子系统相比，机械上更简单并且产生较少有害的副作用。

    SPRAY CLEANER ACCESSORY FOR REACTOR COMPONENT CLEANING
    73.
    发明申请
    SPRAY CLEANER ACCESSORY FOR REACTOR COMPONENT CLEANING 审中-公开
    喷雾清洁剂附件，用于反应器组分清洗

    公开(公告)号：US20130149201A1

    公开(公告)日：2013-06-13

    申请号：US13315609

    申请日：2011-12-09

    申请人： Kim Van Berkel

    发明人： Kim Van Berkel

    IPC分类号： B08B9/093 ,  B01J19/26

    CPC分类号： B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00306 ,  B01J2219/0036 ,  B01J2219/00418 ,  B01J2219/00481 ,  B08B3/024 ,  B08B5/026 ,  H01L21/67051

    摘要： A reactor assembly including a first block having an array of reactors defined therein and a second block having an array of nozzles. The array of nozzles extends from a surface of the second block, the array of nozzles substantially aligned with the array of reactors so that each reactor is associated with a corresponding nozzle extending into a processing region of each reactor in the array of reactors when the surface of the second block is placed on a surface of the first block. Each nozzle of the array of nozzles has a plurality of openings disposed over a surface of the nozzle for dispersing fluid into the corresponding reactor. The array of nozzles is in fluid communication with a fluid source through a network of channels defined within the second block.

    摘要翻译： 一种反应器组件，包括具有限定在其中的反应器阵列的第一块和具有喷嘴阵列的第二块。 喷嘴阵列从第二块的表面延伸，喷嘴阵列基本上与反应堆阵列对齐，使得每个反应器与相应的喷嘴相关联，该喷嘴延伸到反应器阵列中的每个反应器的处理区域中，当表面 的第二块的放置在第一块的表面上。 喷嘴阵列的每个喷嘴具有设置在喷嘴表面上的多个开口，用于将流体分散到相应的反应器中。 喷嘴阵列通过限定在第二块内的通道网络与流体源流体连通。

    SOL-GEL KIT FOR PREPARING BIOCHIP AND METHOD FOR PREPARING BIOCHIP USING THE SAME
    76.
    发明申请
    SOL-GEL KIT FOR PREPARING BIOCHIP AND METHOD FOR PREPARING BIOCHIP USING THE SAME 有权
    用于制备生物化学品的溶胶凝胶试剂盒及其制备方法

    公开(公告)号：US20120277108A1

    公开(公告)日：2012-11-01

    申请号：US13096991

    申请日：2011-04-28

    申请人： Minjoung JO ,  Seram Lee

    发明人： Minjoung JO ,  Seram Lee

    IPC分类号： C40B30/04 ,  C40B30/00 ,  C40B60/14 ,  C40B50/08

    CPC分类号： B01J19/0046 ,  B01J2219/00315 ,  B01J2219/0036 ,  B01J2219/00364 ,  B01J2219/00385 ,  B01J2219/00599 ,  B01J2219/00637 ,  B01J2219/00644 ,  B01J2219/00657 ,  B01J2219/00725

    摘要： A method of preparing a protein chip by gelation of a sol composition. In the method, a mixture of specific silicate monomers, such as SolB1, SolB2 and SolB3, SolBH, and a mixture of SolBS, distilled water and a detector protein are mixed sequentially, so that the gelation rate of the sol composition can be delayed, thus inducing the stable gelation of the composition. Also, the biochip can be fabricated in a simple and easy manner by dispensing the sol composition by hand using an arrayer or a tool such as a pipette. In addition, a uniform biochip can be prepared by dispensing the sol composition, solution I (SolBH) and solution II (a mixture of buffer, SolBS, distilled water and a detector protein) sequentially onto a substrate without needing a conventional pretreatment process such as mixing.

    摘要翻译： 一种通过凝胶化溶胶组合物制备蛋白质芯片的方法。 在该方法中，依次混合特定硅酸盐单体如SolB1，SolB2和SolB3，SolBH和SolBS，蒸馏水和检测器蛋白的混合物的混合物，使得溶胶组合物的凝胶化速率可以延迟， 从而导致组合物的稳定凝胶化。 此外，生物芯片可以通过使用排液器或诸如移液管的工具通过手动分配溶胶组合物以简单和容易的方式制造。 此外，可以通过将溶胶组合物溶液I（SolBH）和溶液II（缓冲液，SolBS，蒸馏水和检测器蛋白质的混合物）顺序分配到基底上而不需要常规的预处理过程例如 混合。

    Dual path gas distribution device
    77.
    发明授权
    Dual path gas distribution device 失效
    双路气体分配装置

    公开(公告)号：US08293013B2

    公开(公告)日：2012-10-23

    申请号：US12346195

    申请日：2008-12-30

    申请人： Jay Brian DeDontney

    发明人： Jay Brian DeDontney

    IPC分类号： C23C16/455 ,  C23C16/44 ,  C23F1/00 ,  H01L21/306 ,  C23C16/06 ,  C23C16/22

    CPC分类号： C23C16/45565 ,  B01J19/0046 ,  B01J2219/0036 ,  B01J2219/00376 ,  B01J2219/00418 ,  B01J2219/00443 ,  B01J2219/00495 ,  B01J2219/00536 ,  B01J2219/00603 ,  B01J2219/00698 ,  C23C16/45574 ,  C23C16/45578 ,  Y10T29/49764 ,  Y10T137/0318

    摘要： An apparatus for deploying two fluids separately into a reaction chamber is provided. The apparatus includes a first distribution network that is formed on a plate having a distribution face and a dispensing face. The first distribution network is defined by a plurality of recessed channels on the distribution face. The plurality of recessed channels includes a plurality of thru-ports that extend from the plurality of recessed channels to the dispensing face. The apparatus further includes a second distribution network that has passages formed below the plurality of recessed channels and above the dispensing face. A first set of ports extends from the passages to the distribution face and a second set of ports extends from a top surface of the distribution face to the dispensing face.

    摘要翻译： 提供了一种用于将两种流体单独地部署到反应室中的装置。 该装置包括形成在具有分配面和分配面的板上的第一分配网络。 第一分配网络由分配面上的多个凹陷通道限定。 多个凹陷通道包括从多个凹陷通道延伸到分配面的多个通孔。 该装置还包括第二分配网络，其具有形成在多个凹陷通道下方并且在分配面上方的通道。 第一组端口从通道延伸到分配面，并且第二组端口从分配面的顶表面延伸到分配面。