-
61.发明授权System and method of manufacturing a composite structure in a closed cavity mold 有权在闭合腔模具中制造复合结构的系统和方法公开(公告)号：US09381679B2
公开(公告)日：2016-07-05
申请号：US13404111
申请日：2012-02-24
CPC分类号： B29C70/46 , B29C33/20 , B29C33/202 , B29C35/02 , B29C2035/0822 , B29K2105/0872 , B29L2031/082
摘要： The present application relates to a method and system that can be utilized to manufacturing composite structures in a closed cavity mold. The tool system includes a closed cavity tool with spring members that when in compression apply pressure to a preform located within the closed cavity mold. During a curing cycle, the spring members provide substantially constant pressure to the preform, thereby preventing voids and porosity in the cured composite structure. Further, the substantially constant pressure, provided by the spring members, acts to more effectively conform the preform to the geometry defined by a void in the closed cavity mold during the curing cycle.
摘要翻译： 本申请涉及一种可用于在闭合腔模具中制造复合结构的方法和系统。 工具系统包括具有弹簧构件的闭合腔工具，其在压缩时对位于封闭空腔模具内的预成型件施加压力。 在固化循环期间，弹簧构件为预制件提供基本恒定的压力，从而防止固化的复合结构中的空隙和孔隙。 此外，由弹簧构件提供的基本上恒定的压力用于在固化周期期间更有效地使预制件与由闭合空腔模具中的空隙限定的几何形状相一致。
-
公开(公告)号：US09186507B2
公开(公告)日：2015-11-17
申请号：US11506619
申请日：2006-08-17
CPC分类号： A61N1/36046
摘要： The present invention is a method of improving the persistence of electrical neural stimulation, and specifically a method of improving the persistence of an image supplied to a retina, or visual cortex, through a visual prosthesis. A continuously stimulated retina, or other neural tissue, will desensitize after a time period in the range of 20 to 150 seconds. However, an interruption of the stimulation on the order of a few milliseconds will restore the retinal sensitivity without the user perceiving the interruption, or with the user barely perceiving the interruption.
-
63.发明授权Molded polymer comprising silicone and at least one metal trace and a process of manufacturing the same 有权包含有机硅和至少一种金属痕迹的成型聚合物及其制造方法公开(公告)号：US09185810B2
公开(公告)日：2015-11-10
申请号：US11924752
申请日：2007-10-26
IPC分类号： B29D11/00 , B05D3/06 , B05D5/12 , H05K3/18 , C25D5/02 , C25D5/56 , C23C18/16 , C23C18/18 , C23C18/20 , H05K1/03 , H05K3/00 , H05K3/28 , H05K3/42 , H05K3/46
CPC分类号： H05K3/185 , C23C18/1612 , C23C18/1639 , C23C18/1641 , C23C18/1692 , C23C18/1868 , C23C18/204 , C25D5/02 , C25D5/56 , H05K1/032 , H05K1/0393 , H05K3/0035 , H05K3/28 , H05K3/421 , H05K3/4661 , H05K2201/0162
摘要： The invention is a method of making a flexible electrode array, comprising a silicone containing body, a metal trace layer and an electrode pad on the surface, including the steps of irradiating a surface area of a molded silicone containing layer yielding traces with the light beam from a pulsed ultraviolet laser source; immersing said irradiated molded silicone layer for inducing the deposit of metal ions to form metal traces; applying a silicone containing layer on the silicone containing layer and the metal traces; irradiating the surface for drilling holes in the molded silicone containing layer; and immersing the irradiated molded silicone layer for inducing the deposit of metal ions to form metal electrode pads.
摘要翻译： 本发明是一种制造柔性电极阵列的方法，该方法包括含硅体的物质，金属迹线层和表面上的电极焊盘，包括以下步骤：用模塑的含硅氧烷的层的表面积照射光束 来自脉冲紫外激光源; 浸渍所述照射的模制的硅氧烷层以诱导金属离子的沉积形成金属痕迹; 在含硅树脂层和金属迹线上涂覆含硅氧烷层; 照射表面用于在模塑的含硅树脂层中钻孔; 并将用于诱导金属离子沉积的照射的模制硅氧烷层浸渍以形成金属电极焊盘。
-
公开(公告)号：US09095722B2
公开(公告)日：2015-08-04
申请号：US11343170
申请日：2006-01-30
申请人： Brian Mech , Robert J. Greenberg , Honggang Jiang
发明人： Brian Mech , Robert J. Greenberg , Honggang Jiang
CPC分类号： A61N1/37205 , A61N1/05 , A61N1/372 , A61N1/375 , C23C14/081 , C23C14/28
摘要： An implantable micro-miniature device is disclosed. The device comprises a thin hermetic insulating coating and at least one thin polymer or metal secondary coating over the hermetic insulating layer in order to protect the insulating layer from the erosive action of body fluids or the like. In one embodiment the insulating layer is ion beam assisted deposited (IBAD) alumina and the secondary coating is a parylene polymer. The device may be a small electronic device such as a silicon integrated circuit chip. The thickness of the insulating layer may be ten microns or less and the thickness of the secondary layer may be between about 0.1 and about 15 microns.
摘要翻译： 公开了一种可植入微型装置。 该装置包括薄的气密绝缘涂层和在密封绝缘层上的至少一个薄聚合物或金属二次涂层，以保护绝缘层免受体液等的侵蚀作用。 在一个实施例中，绝缘层是离子束辅助沉积（IBAD）氧化铝，第二涂层是聚对二甲苯聚合物。 该器件可以是诸如硅集成电路芯片的小型电子器件。 绝缘层的厚度可以为10微米或更小，并且第二层的厚度可以在约0.1至约15微米之间。
-
65.发明授权Biocompatible bonding method and electronics package suitable for implantation 有权生物相容性接合方法和电子封装适合植入公开(公告)号：US08880165B2
公开(公告)日：2014-11-04
申请号：US13009769
申请日：2011-01-19
申请人： Robert J. Greenberg , Neil Talbot , Jerry Ok , Jordan Neysmith , Dao Min Zhou
发明人： Robert J. Greenberg , Neil Talbot , Jerry Ok , Jordan Neysmith , Dao Min Zhou
IPC分类号： A61N1/00 , A61N1/36 , A61N1/05 , A61N1/375 , H01L23/498 , H05K3/36 , H05K1/03 , H05K3/46 , H05K3/32 , H05K3/42 , H01L21/56 , H05K3/40
CPC分类号： A61N1/3758 , A61N1/0543 , A61N1/36046 , A61N1/375 , H01L21/563 , H01L23/49827 , H01L23/49838 , H01L23/4985 , H01L24/81 , H01L2224/0557 , H01L2224/05571 , H01L2224/05573 , H01L2224/13169 , H01L2224/13178 , H01L2224/16225 , H01L2224/16227 , H01L2224/32225 , H01L2224/73204 , H01L2224/81469 , H01L2224/81478 , H01L2224/81815 , H01L2924/00014 , H01L2924/01019 , H01L2924/01046 , H01L2924/01077 , H01L2924/01078 , H01L2924/01079 , H01L2924/14 , H01L2924/1461 , H05K1/028 , H05K1/0306 , H05K1/09 , H05K1/111 , H05K1/113 , H05K1/115 , H05K1/189 , H05K3/10 , H05K3/188 , H05K3/305 , H05K3/321 , H05K3/328 , H05K3/3436 , H05K3/361 , H05K3/4015 , H05K3/4038 , H05K3/4084 , H05K3/423 , H05K3/4644 , H05K3/4652 , H05K3/4691 , H05K13/0469 , H05K2201/09127 , H05K2201/1028 , H05K2201/10287 , H05K2201/10295 , H05K2201/10977 , H05K2203/05 , H05K2203/06 , H05K2203/0733 , H05K2203/09 , H05K2203/107 , H05K2203/1446 , H01L2924/00 , H01L2224/05599
摘要： The invention is directed to a method of bonding a hermetically sealed electronics package to an electrode or a flexible circuit and the resulting electronics package, that is suitable for implantation in living tissue, such as for a retinal or cortical electrode array to enable restoration of sight to certain non-sighted individuals. The hermetically sealed electronics package is directly bonded to the flex circuit or electrode by electroplating a biocompatible material, such as platinum or gold, effectively forming a plated rivet-shaped connection, which bonds the flex circuit to the electronics package. The resulting electronic device is biocompatible and is suitable for long-term implantation in living tissue.
摘要翻译： 本发明涉及一种将气密密封的电子封装结合到电极或柔性电路的方法以及所得到的电子封装，其适于植入生物组织，例如用于视网膜或皮质电极阵列，以使视力恢复 对某些无意识的个人。 电气密封的电子封装通过电镀生物相容性材料（例如铂或金）直接结合到柔性电路或电极上，有效地形成电镀铆钉形连接，其将柔性电路连接到电子封装。 所得到的电子装置是生物相容的并且适合长期植入生物体组织。
-
公开(公告)号：US08630720B2
公开(公告)日：2014-01-14
申请号：US13474003
申请日：2012-05-17
申请人： Brian V. Mech , Robert J. Greenberg
发明人： Brian V. Mech , Robert J. Greenberg
IPC分类号： A61N1/00
CPC分类号： C23C16/274 , A61K9/0009 , A61N1/0543 , A61N1/36046 , A61N1/375 , C23C16/277 , C23C16/278 , C23C16/279 , H01L23/29 , H01L23/3107 , H01L2924/0002 , H01L2924/00
摘要： An implantable biocompatible electrical device is uniformly covered with a coating approximately one-micron thick of ultra-nanocrystalline diamond, hermetically sealing the electrical device. Selected electrodes are either left uncovered during coating or uncovered by conventional patterning techniques, allowing the electrodes to be exposed to living tissue and fluids. The ultra-nanocrystalline diamond coating may be doped to create electrically conductive electrodes. These approaches eliminate the need for a hermetically sealed lid or cover to protect electrical circuitry, and thus allow the device to be thinner than otherwise possible. The conformal ultra-nanocrystalline diamond coating uniformly covers the device, providing relief from sharp edges and producing a strong, uniformly thick hermetic coating around sharp edges and on high aspect-ratio parts.
摘要翻译： 植入式生物相容性电气装置均匀地覆盖有大约1微米厚的超微晶金刚石的涂层，气密地密封电气装置。 所选择的电极在涂覆期间未被覆盖或者通过常规图案化技术未被覆盖，允许电极暴露于活组织和流体。 超级纳米晶体金刚石涂层可以被掺杂以产生导电电极。 这些方法消除了对密封的盖或盖的需要以保护电路，并且因此允许该装置比其它可能的更薄。 保形的超纳米晶金刚石涂层均匀地覆盖了该装置，从尖锐的边缘提供浮雕，并在尖锐的边缘和高纵横比的部分上产生强而均匀的厚的密封涂层。
-
公开(公告)号：US08588937B2
公开(公告)日：2013-11-19
申请号：US13360491
申请日：2012-01-27
IPC分类号： A61N1/00
CPC分类号： A61N1/0543 , A61N1/0558
摘要： An electrode array attached to neural tissue, such as the retina, necessarily has graded pressure exerted on the tissue, with higher pressure near the attachment point. Greater pressure improves contact between the electrodes and neural tissue while too much pressure may damage neural tissue. Hence it is advantageous to obtain equal pressure across the array field. In the present invention a central attachment point in the electrode field applies the most even pressure. Further, multiple and selective attachment points may be additionally provided on an electrode array allowing a surgeon to select the attachment points providing the best electrode tissue contact.
摘要翻译： 附着到神经组织（例如视网膜）上的电极阵列必须具有施加在组织上的分级压力，附近点附近具有更高的压力。 更大的压力改善了电极和神经组织之间的接触，而太多的压力可能损伤神经组织。 因此，有利的是在阵列场上获得相等的压力。 在本发明中，电极领域中的中心附着点施加最均匀的压力。 此外，可以在电极阵列上额外提供多个和选择性附着点，允许外科医生选择提供最佳电极组织接触的附接点。
-
公开(公告)号：US08527062B2
公开(公告)日：2013-09-03
申请号：US12416824
申请日：2009-04-01
申请人： Rongqing Dai , Robert J. Greenberg
发明人： Rongqing Dai , Robert J. Greenberg
IPC分类号： A61N1/08
CPC分类号： A61N1/378 , A61N1/36046
摘要： A power scheme for an implant on a human or animal body comprises: a charging circuit to provide power to deliver controlled stimulation currents to a body tissue; a capacitive storage arrangement connected with the charging circuit and charged by the charging circuit; a shunting arrangement to limit voltage on the capacitive storage arrangement; a driver array configured to transfer charges from the capacitive storage arrangement to the tissue; and an electrode array connected with the driver array and the tissue.
-
公开(公告)号：US08515543B2
公开(公告)日：2013-08-20
申请号：US13417604
申请日：2012-03-12
IPC分类号： A61N1/00
CPC分类号： A61N1/0543 , A61N1/0558
摘要： The present invention is an electrode array for neural stimulation. In particular it is an electrode array for use with a visual prosthesis with the electrode array suitable to be positioned on the retina. The array includes multiple attachment points to provide for even pressure across the electrode array surface. The attachment points are arranged so as to not damage retinal tissue stimulated by the electrode array.
摘要翻译： 本发明是用于神经刺激的电极阵列。 特别地，它是用于视觉假体的电极阵列，其中电极阵列适合于定位在视网膜上。 该阵列包括多个连接点，以提供穿过电极阵列表面的均匀的压力。 安装点被布置成不损伤由电极阵列刺激的视网膜组织。
-
公开(公告)号：US08457752B2
公开(公告)日：2013-06-04
申请号：US11521681
申请日：2006-09-15
IPC分类号： A61N1/00
CPC分类号： A61N1/36046 , A61N1/0543
摘要： The present invention is a method of improving the contrast of electrical neural stimulation and expanding the dynamic range for brightness, and specifically a method of improving the contrast of an image supplied to the retina, or visual cortex, through a visual prosthesis. The background brightness for a blind subject is often not perfectly black, but a dark gray or brown. When stimulating visual neurons in the retina, low current stimulation tends to create a dark percept, the perception of a phosphene darker than the background brightness level perceived in the un-stimulated state. The human retina contains neurons that signal light increments (“on” cells) and neurons that signal light decrements (“off” cells). In a healthy retina, the on cells tend to fire in response to an increase in light above the background level, while the off cells tend to fire in response to a decrease in light below the background level.
摘要翻译： 本发明是改善电神经刺激的对比度和扩大亮度的动态范围的方法，具体而言，是通过视觉假体改善提供给视网膜或视觉皮层的图像的对比度的方法。 盲人的背景亮度通常不是完全黑色，而是深灰色或棕色。 当刺激视网膜中的视觉神经元时，低电流刺激倾向于产生暗感知，磷光体的感知比在未刺激状态下感知到的背景亮度水平更暗。 人类视网膜含有信号光增量（“on”细胞）和信号光衰减（“off”细胞）的神经元的神经元。 在健康的视网膜中，上细胞倾向于响应于高于背景水平的光的增加而起火，而离开细胞倾向于响应于低于背景水平的光的降低而起火。
-
-
-
-
-
-
-
-
-
搜索结果
280 条记录 (耗时 0.027 秒)
