公开(公告)号：US20180229039A1

公开(公告)日：2018-08-16

申请号：US15897014

申请日：2018-02-14

Applicant: THE CHARLES STARK DRAPER LABORATORY, INC.

Inventor： Jesse J. Wheeler ,  John Lachapelle ,  Caroline K. Bjune ,  Philip D. Parks, II ,  Carlos A. Segura

IPC: A61N1/36 ,  A61N1/365 ,  A61N1/372

CPC classification number: A61N1/05 ,  A61B5/04001 ,  A61B5/04004 ,  A61B5/04012 ,  A61B5/0492 ,  A61B5/6847 ,  A61B5/6877 ,  A61B2562/028 ,  A61B2562/04 ,  A61B2562/125 ,  A61N1/0404 ,  A61N1/0502 ,  A61N1/0504 ,  A61N1/36 ,  A61N1/36003 ,  A61N1/3606 ,  A61N1/36062 ,  A61N1/36114 ,  A61N1/36125 ,  A61N1/36128 ,  A61N1/365 ,  A61N1/37211

Abstract: A lead assembly for networked implants may contain a controller, an implantable tissue contact system connected to the controller and including a plurality of leads, and a breakout connector connected to each of the plurality of leads, and further connected to a shared communication path. A physiological interface system may contain a controller and an implantable tissue contact system. Methods of treating a subject and monitoring a subject include transmitting signals between a controller and an implantable tissue contact system.

公开(公告)号：US20180214076A1

公开(公告)日：2018-08-02

申请号：US15918142

申请日：2018-03-12

Applicant: Accuvein, Inc.

Inventor： Ron Goldman ,  David Hunt ,  Mark Mock ,  Graham Marshall ,  Stephen P. Conlon ,  Robert Roth

IPC: A61B5/00 ,  A61M5/42 ,  A61B17/34

CPC classification number: A61B5/489 ,  A61B5/0037 ,  A61B5/0059 ,  A61B5/0062 ,  A61B5/0068 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0079 ,  A61B5/0082 ,  A61B5/6824 ,  A61B5/6831 ,  A61B5/6887 ,  A61B5/743 ,  A61B5/7475 ,  A61B17/3403 ,  A61B90/13 ,  A61B2090/366 ,  A61B2560/0214 ,  A61B2560/0425 ,  A61B2560/0431 ,  A61B2562/028 ,  A61M5/427 ,  A61M5/46

Abstract: The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like.

公开(公告)号：US20180199841A1

公开(公告)日：2018-07-19

申请号：US15876030

申请日：2018-01-19

Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA

Inventor： Zhi Yang ,  Jian Xu ,  Anh Tuan Nguyen ,  Tong Wu

IPC: A61B5/04 ,  A61B5/00

CPC classification number: A61B5/04001 ,  A61B5/4041 ,  A61B5/4064 ,  A61B5/4836 ,  A61B5/685 ,  A61B5/686 ,  A61B5/7203 ,  A61B5/7217 ,  A61B5/7225 ,  A61B2505/09 ,  A61B2562/028 ,  A61B2562/043 ,  A61B2562/046 ,  A61B2562/166

Abstract: An implantable neuromodulation system is provided comprising at least one stimulation microelectrode, at least one microelectrode, and a frequency-shaping amplifier (FSA). The at least one stimulation microelectrode is configured to deliver a desired electrical stimulation to a neuronal population. The at least one recording microelectrode is configured to receive neural signals from the neuronal population. The FSA is coupled to the at least one recording microelectrode. The FSA is configured to allow for simultaneous electrical recording and electrical stimulation of the neuronal population.

公开(公告)号：US10012651B2

公开(公告)日：2018-07-03

申请号：US15169365

申请日：2016-05-31

Applicant: ANPAC Bio-Medical Science Co., Ltd.

Inventor： Chris C Yu ,  Xuedong Du ,  He Yu

IPC: G01N33/53 ,  G01N15/10 ,  G01N33/574 ,  G01N33/50 ,  B01L3/00 ,  C12Q1/68 ,  G01N1/34 ,  A61B5/07 ,  A61B5/145 ,  A61B10/00 ,  G01N1/40 ,  G01N15/14 ,  G01N33/487 ,  C12M1/34 ,  G01N33/543 ,  G01N15/00

CPC classification number: G01N33/574 ,  A61B5/07 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14528 ,  A61B5/14546 ,  A61B10/0041 ,  A61B2562/028 ,  A61B2562/12 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502761 ,  B01L2200/0647 ,  B01L2200/0652 ,  B01L2200/0663 ,  B01L2200/0668 ,  B01L2300/0627 ,  B01L2300/0636 ,  B01L2300/0645 ,  B01L2300/0681 ,  B01L2300/0858 ,  B01L2300/0887 ,  B01L2300/123 ,  B01L2300/163 ,  B01L2400/0487 ,  C12Q1/68 ,  G01N1/34 ,  G01N1/4077 ,  G01N15/1056 ,  G01N15/1484 ,  G01N33/487 ,  G01N33/5091 ,  G01N33/54366 ,  G01N2001/4088 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2015/1062 ,  G01N2015/1486

Abstract: Among others, the present invention provides apparatus for interacting with a biological subject to detect circulating tumor cells therein, comprising one device for sending a signal to the biological subject and optionally receiving a response to the signal from the biological entity.

公开(公告)号：US10004453B2

公开(公告)日：2018-06-26

申请号：US15250469

申请日：2016-08-29

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Il-Joo Cho ,  Eui Sung Yoon ,  Hyogeun Shin ,  Uikyu Chae ,  Hyunjoo Jenny Lee

IPC: A61M5/32 ,  A61B5/00 ,  A61B5/04 ,  A61M5/158 ,  A61M39/10

CPC classification number: A61B5/4848 ,  A61B5/04001 ,  A61B5/6848 ,  A61B2562/028 ,  A61M5/158 ,  A61M39/105 ,  A61M2210/0693

Abstract: A neural probe structure has a probe having a microfluidic channel. The probe is inserted into an inside of a subject. A body to which the probe is fixed has a fluid entrance communicating with the microfluidic channel. A cover element is fixed to the body to cover the fluid entrance. The cover element has a connecting opening to which an external conduit is connected, and a fluid delivery channel extending such that the connecting opening and the fluid entrance are in fluid communication. A fluid fed from the external conduit flows along the fluid delivery channel, goes into the fluid entrance, and is delivered to the subject through the microfluidic channel.

公开(公告)号：US20180169414A1

公开(公告)日：2018-06-21

申请号：US15892199

申请日：2018-02-08

Applicant: Cardionomic, Inc.

Inventor： Steven D. Goedeke ,  Mark A. Christopherson ,  David J. Serdar ,  Steven C. Christian

IPC: A61N1/36 ,  A61B5/02 ,  A61B5/0215 ,  A61B5/00 ,  A61B6/00 ,  A61B6/12 ,  A61B5/08 ,  A61M25/10 ,  A61N1/05

CPC classification number: A61B5/4836 ,  A61B5/02028 ,  A61B5/02158 ,  A61B5/0422 ,  A61B5/0452 ,  A61B5/0823 ,  A61B5/4848 ,  A61B5/6858 ,  A61B5/6859 ,  A61B5/7246 ,  A61B6/12 ,  A61B6/487 ,  A61B18/1492 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00279 ,  A61B2018/00285 ,  A61B2018/00351 ,  A61B2018/00839 ,  A61B2562/0247 ,  A61B2562/028 ,  A61M25/10 ,  A61M2025/0003 ,  A61N1/0558 ,  A61N1/056 ,  A61N1/0573 ,  A61N1/36017 ,  A61N1/36114 ,  A61N1/36117 ,  A61N1/36135 ,  A61N1/36139 ,  A61N1/36146 ,  A61N1/36185 ,  A61N1/3627 ,  A61N1/36585 ,  A61N2001/058

Abstract: A device includes a handle, an expandable structure including a plurality of splines extending from a proximal hub to a distal hub, a first electrode on a first spline of the plurality of splines, an outer tube extending from the handle to the proximal hub, and a shaft extending through the outer tube from the handle to the distal hub. The expandable structure has a collapsed state and a self-expanded state. The handle is configured to retract the shaft. Retracting the shaft may expand the expandable structure outward of the self-expanded state.

公开(公告)号：US09989522B2

公开(公告)日：2018-06-05

申请号：US13478356

申请日：2012-05-23

Applicant: Jesper Svenning Kristensen ,  Tri T. Dang ,  Katharine Knarreborg ,  Anubhuti Bansal

Inventor： Jesper Svenning Kristensen ,  Tri T. Dang ,  Katharine Knarreborg ,  Anubhuti Bansal

IPC: C12Q1/54 ,  G01N33/52 ,  G01N33/487 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/1486 ,  G01N21/77

CPC classification number: G01N33/525 ,  A61B5/145 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/14556 ,  A61B5/14865 ,  A61B5/6861 ,  A61B2562/02 ,  A61B2562/028 ,  A61B2562/162 ,  G01N21/77 ,  G01N33/487

Abstract: The invention relates to sensors configured to include compositions disposed in specific regions of the sensor in order to provide the sensors with enhanced functional properties, for example faster start-up times. These compositions include, for example, hygroscopic compositions, gas generating compositions and gas solvating compositions. While typical embodiments of the invention pertain to glucose sensors, the systems, methods and materials disclosed herein can be adapted for use with a wide variety of sensors known in the art.

公开(公告)号：US20180125590A1

公开(公告)日：2018-05-10

申请号：US15807836

申请日：2017-11-09

Applicant: Ethicon LLC

Inventor： James R. Giordano ,  Jeffrey S. Swayze ,  Frederick E. Shelton, IV

IPC: A61B17/072 ,  A61B17/10 ,  B65B5/04 ,  A61B17/295 ,  B65B55/18 ,  A61B17/32 ,  B65B55/16 ,  A61B17/00 ,  A61B17/068 ,  A61B17/122 ,  A61B17/29

CPC classification number: A61B34/30 ,  A61B17/00234 ,  A61B17/068 ,  A61B17/072 ,  A61B17/07207 ,  A61B17/105 ,  A61B17/1222 ,  A61B17/295 ,  A61B17/32 ,  A61B34/71 ,  A61B50/36 ,  A61B90/98 ,  A61B2017/00022 ,  A61B2017/00039 ,  A61B2017/00212 ,  A61B2017/00221 ,  A61B2017/00362 ,  A61B2017/00398 ,  A61B2017/00473 ,  A61B2017/00477 ,  A61B2017/00685 ,  A61B2017/00734 ,  A61B2017/07214 ,  A61B2017/07271 ,  A61B2017/07278 ,  A61B2017/07285 ,  A61B2017/2927 ,  A61B2017/2943 ,  A61B2017/320093 ,  A61B2017/320094 ,  A61B2017/320095 ,  A61B2017/320097 ,  A61B2034/2053 ,  A61B2034/2059 ,  A61B2034/2072 ,  A61B2034/302 ,  A61B2090/065 ,  A61B2090/0811 ,  A61B2090/0814 ,  A61B2562/028 ,  B65B5/04 ,  B65B55/16 ,  B65B55/18

Abstract: A surgical instrument, such as an endoscopic or laparoscopic instrument. The surgical instrument may comprise an end effector comprising at least one sensor. The surgical instrument may also comprise an electrically conductive shaft having a distal end connected to the end effector wherein the sensor is electrically insulated from the shaft. The surgical instrument may also comprise a handle connected to a proximate end of the shaft. The handle may comprise a control unit electrically coupled to the shaft such that the shaft radiates signals as an antenna from the control unit to the sensor and receives radiated signals from the sensor. Other components electrically coupled to the shaft may also radiate the signals.

公开(公告)号：US09958444B2

公开(公告)日：2018-05-01

申请号：US14292740

申请日：2014-05-30

Applicant: Scott W. T. Chen ,  John T. Carroll ,  Raafat R. Mansour

Inventor： Scott W. T. Chen ,  John T. Carroll ,  Raafat R. Mansour

IPC: G01N33/545 ,  A61B5/145 ,  G01N33/483 ,  A61B5/1477 ,  A61B5/00

CPC classification number: G01N33/545 ,  A61B5/14546 ,  A61B5/1477 ,  A61B5/4845 ,  A61B5/681 ,  A61B5/6893 ,  A61B2562/028 ,  A61B2562/06 ,  G01N33/4836

Abstract: According to one aspect, a system for sensing ethanol from human skin, that comprises at least one apparatus for sensing ethanol and a coupling matrix readout extraction unit for performing a method of extracting a coupling-matrix readout. The at least one sensing apparatus and the coupling matrix readout extraction may be mounted on a substrate. The substrate may be adapted such that it can be formed into a wearable accessory that can be worn by a human subject. When the wearable accessory is worn by the human subject such that the subject provides a skin tissue sample to the accessory, the presence or concentration of ethanol and other compounds may be determined from the vapor associated with the tissue sample.

公开(公告)号：US09955938B2

公开(公告)日：2018-05-01

申请号：US14314799

申请日：2014-06-25

Applicant: ZOLL MEDICAL CORPORATION

Inventor： Thomas E. Kaib

IPC: A61B5/00 ,  A61B5/04 ,  A61B7/04 ,  G10L25/48 ,  A61B5/0408 ,  A61N1/04

CPC classification number: A61B7/04 ,  A61B5/04085 ,  A61B5/6833 ,  A61B2562/0219 ,  A61B2562/028 ,  A61N1/0484 ,  G10L25/48

Abstract: Disclosed herein are methods and apparatus including medical devices having features for monitoring sounds and motions indicative of a state of health or administration of CPR to a subject. In one embodiment, a therapeutic device such as a therapy electrode comprises a layer configured to deliver a therapy to a subject and an acoustic sensor on the therapeutic device and coupled to the layer.