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1466 条记录 (耗时 0.031 秒)

    ARTIFICIAL BONE NANOCOMPOSITE AND METHOD OF MANUFACTURE
    91.
    发明申请
    ARTIFICIAL BONE NANOCOMPOSITE AND METHOD OF MANUFACTURE 有权
    人造骨NANOCOMPOSITE和制造方法

    公开(公告)号：US20150231304A1

    公开(公告)日：2015-08-20

    申请号：US14684939

    申请日：2015-04-13

    申请人： Samin Eftekhari

    发明人： Samin Eftekhari ,  Habiba Bougherara

    IPC分类号： A61L27/48 ,  A61L27/56 ,  D01D5/00 ,  A61L27/46

    CPC分类号： A61L27/48 ,  A61L27/46 ,  A61L27/56 ,  A61L31/127 ,  A61L31/129 ,  A61L31/146 ,  A61L2400/12 ,  A61L2430/02 ,  D01D5/00 ,  C08L67/04

    摘要： A composition suitable for bone replacement is provided. The composition is a nanocomposite matrix, resembling both the structure and the properties of natural bone, including morphology, composition and mechanical characteristics. The nanocomposite is preferably porous and comprises: (1) micro or nano scale cellulose crystals or fibres; (2) hydroxyapatite nanoparticles; (3) Poly L-Lactide Acid or poly glycolic acid; and (4) a coupling agent, for example a surfactant, preferably an anionic surfactant such as sodium dodecyl sulfate. The composition is useful as an artificial bone replacement or bone graft, is preferably biomimetic, and can be suitable for use, for example, in trabecular bone substitution and osteoanagenesis applications. A method of fabrication of the nanocomposite is also provided.

    摘要翻译： 提供了适合于骨替代的组合物。 该组合物是纳米复合物基质，类似天然骨的结构和性质，包括形态，组成和机械特性。 纳米复合材料优选是多孔的，并且包括：（1）微米或纳米级纤维素晶体或纤维; （2）羟基磷灰石纳米粒子; （3）聚L-丙交酯酸或聚乙醇酸; 和（4）偶联剂，例如表面活性剂，优选阴离子表面活性剂如十二烷基硫酸钠。 组合物可用作人造骨置换或骨移植，优选是仿生的，并且可适用于例如小梁骨取代和骨诱导应用。 还提供了纳米复合材料的制造方法。

    Thin bendable bone plate for bone deficit repair and method of preparation
    93.
    发明授权
    Thin bendable bone plate for bone deficit repair and method of preparation 有权
    用于骨缺损修复的薄弯骨骨板及其制备方法

    公开(公告)号：US09101424B1

    公开(公告)日：2015-08-11

    申请号：US14543234

    申请日：2014-11-17

    申请人： Theodore Malinin

    发明人： Theodore Malinin

    IPC分类号： A61B17/80

    CPC分类号： A61B17/8085 ,  A61B2017/00526 ,  A61L31/005 ,  A61L31/146 ,  A61L2430/02 ,  Y10T83/0405

    摘要： A flexible, bendable organic decalcified or partially decalcified bone, cortical or cancellous, adapted for use in augmentation or repair of animal skeletal structures comprising a continuous plate or sheet of natural bone, as well as dermis is described. The thickness, flexibility and tensile strength of the construct is such as to allow it to be shaped and contoured without damage to it. The composition is ultimately remodeled by the body, thus obviating the need for additional surgical intervention. The clinical indications for the use of the invented construct are many, but are particularly prominent in dentistry, oral and maxillofacial surgery and implantology. It is particularly useful in the maxillary sinus augmentation. A unique new method, different from previously described methods for the preparation of the disclosed constructs, is described.

    摘要翻译： 描述适用于增强或修复包括天然骨的连续板或片的动物骨骼结构以及真皮的柔性的，可弯曲的有机脱钙或部分脱钙的骨，皮层或松质骨。 构造物的厚度，柔韧性和拉伸强度使得其可以成形和成型而不损坏其。 组合物最终被身体重塑，从而避免了额外的手术干预的需要。 使用本发明构造物的临床适应症很多，但在牙科，口腔和颌面外科学和种植学中尤为突出。 它在上颌窦扩大中特别有用。 描述了与用于制备所公开的构建体的先前描述的方法不同的独特的新方法。

    Vascular Stents and Related Methods
    95.
    发明申请
    Vascular Stents and Related Methods 有权
    血管支架及相关方法

    公开(公告)号：US20150164664A1

    公开(公告)日：2015-06-18

    申请号：US14533979

    申请日：2014-11-05

    申请人： Brigham Young University

    发明人： Darrell J. Skousen ,  Brian D. Jensen ,  Anton E. Bowden

    IPC分类号： A61F2/89

    CPC分类号： A61F2/915 ,  A61F2/82 ,  A61F2/844 ,  A61F2/86 ,  A61F2002/91558 ,  A61F2002/91575 ,  A61F2002/91583 ,  A61F2210/0014 ,  A61F2250/0036 ,  A61L31/122 ,  A61L31/146 ,  A61L2400/12 ,  B29C59/007 ,  B82Y40/00

    摘要： A vascular stent assembly includes at least a first and a second strut, each including a thickness and a depth. The assembly includes a pair of end radii, with each of the first and second struts extending from one of the pair of end radii. A thickness of at least one of the first and second struts includes a tapering profile extending from one of the end radii to another of the end radii, the tapering profile following a continuously increasing or decreasing function through at least half a length of the at least one strut.

    摘要翻译： 血管支架组件包括至少第一和第二支柱，每个支柱包括厚度和深度。 组件包括一对端部半径，第一和第二支柱中的每一个从一对端部半径中的一个延伸。 所述第一和第二支柱中的至少一个的厚度包括从所述端部半径之一延伸到所述端部半径中的另一个的锥形轮廓，所述锥形轮廓沿连续增加或减小的功能通过所述至少一半的长度 一个支柱

    Bioactive glass scaffolds, and method of making
    98.
    发明授权
    Bioactive glass scaffolds, and method of making 有权
    生物活性玻璃支架及其制造方法

    公开(公告)号：US09045362B2

    公开(公告)日：2015-06-02

    申请号：US13836207

    申请日：2013-03-15

    申请人： MOSCI CORP.

    发明人： Steven Jung

    IPC分类号： C03B19/06 ,  C03B19/10 ,  C03C4/00

    CPC分类号： C03B19/06 ,  A61F2/28 ,  A61L15/08 ,  A61L24/0036 ,  A61L24/02 ,  A61L27/10 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L31/026 ,  A61L31/146 ,  A61L2300/102 ,  A61L2430/02 ,  A61L2430/34 ,  C03B19/108 ,  C03B19/109 ,  C03B32/02 ,  C03C3/04 ,  C03C4/0007 ,  C03C4/0014 ,  C03C11/00 ,  C03C2204/00 ,  Y10T428/315

    摘要： A glass, glass-ceramic, or ceramic bead is described, with an internal porous scaffold microstructure that is surrounded by an amorphous shield. The shield serves to protect the internal porous microstructure of the shield while increasing the overall strength of the porous microstructure and improve the flowability of the beads either by themselves or in devices such as biologically degradable putty that would be used in bone or soft tissue augmentation or regeneration. The open porosity present inside the bead will allow for enhanced degradability in-vivo as compared to solid particles or spheres and also promote the growth of tissues including but not limited to all types of bone, soft tissue, blood vessels, and nerves.

    摘要翻译： 描述了玻璃，玻璃陶瓷或陶瓷珠，其具有被无定形屏蔽包围的内部多孔支架微结构。 屏蔽件用于保护屏蔽件的内部多孔微结构，同时增加多孔微结构的总体强度并且通过其本身或在用于骨骼或软组织增大中的生物可降解腻子的装置中提高珠粒的流动性，或 再生。 存在于珠粒内的开放孔隙将允许与固体颗粒或球体相比在体内增强的降解性，并且还促进组织的生长，包括但不限于所有类型的骨，软组织，血管和神经。