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    Process for the production of pseudolatices and micro- or nanoparticles and pharmaceutical preparations containing them
    91.
    发明授权
    Process for the production of pseudolatices and micro- or nanoparticles and pharmaceutical preparations containing them 失效
    用于制备假胶束和含有微粒或纳米颗粒的药物制剂的方法

    公开(公告)号：US5919408A

    公开(公告)日：1999-07-06

    申请号：US531283

    申请日：1995-09-20

    Applicant: Bernd W. Muller ,  Felix Junis-Specht

    Inventor： Bernd W. Muller ,  Felix Junis-Specht

    IPC: A61K9/16 ,  A61K9/19 ,  A61K9/51 ,  C08J3/03 ,  C08J3/12 ,  C08L1/28 ,  C08L93/02 ,  C08J3/16

    CPC classification number: A61K9/5153 ,  A61K9/1647 ,  A61K9/1652 ,  A61K9/5192 ,  B82Y5/00 ,  C08J3/03 ,  C08J3/12 ,  C08L1/28 ,  C08L93/02 ,  Y10S977/788

    Abstract: The invention relates to a process for the production of pseudolatices or micro- and/or nanoparticles, in which a polymer is crystalline, partially crystalline or amorphous, is selected from cellulose derivatives, poly(meth)acrylates, shellac, polylactides, polylactide/polyglycolide mixtures, polyhydroxy butyric acids or polycyanoacrylates and is heated to a temperature above its glass transition temperature and then high-pressure homogenized in water or an aqueous buffer solution and this suspension is converted, if necessary, into micro- and/or nanoparticles by drying. Medicaments can be worked into the pseudolatices, micro- and/or nanoparticles.

    Abstract translation: 本发明涉及一种制备假胶体或微米和/或纳米颗粒的方法，其中聚合物是结晶的，部分结晶的或无定形的，选自纤维素衍生物，聚（甲基）丙烯酸酯，虫胶，聚丙交酯，聚丙交酯/聚乙交酯 混合物，多羟基丁酸或聚氰基丙烯酸酯，并加热到高于其玻璃化转变温度的温度，然后在水或缓冲溶液中高压均质化，如果需要，该悬浮液通过干燥转化成微米和/或纳米颗粒。 可以将药物加工成伪溶剂，微量和/或纳米颗粒。

    Polymer composition, absorbent material composition, their production and their use
    96.
    发明授权
    Polymer composition, absorbent material composition, their production and their use 失效
    聚合物组合物，吸收材料组成，其生产及其用途

    公开(公告)号：US5736595A

    公开(公告)日：1998-04-07

    申请号：US535070

    申请日：1995-11-03

    Applicant: Uwe Gunther ,  Helmut Klimmek ,  Helmut Bruggemann

    Inventor： Uwe Gunther ,  Helmut Klimmek ,  Helmut Bruggemann

    IPC: A61F13/53 ,  A61F13/49 ,  A61L15/28 ,  A61L15/60 ,  B01J20/26 ,  C08J3/20 ,  C08L1/00 ,  C08L1/08 ,  C08L1/28 ,  C08L3/00 ,  C08L3/04 ,  C08L5/00 ,  C08L101/16 ,  C08L1/26 ,  C08L3/08

    CPC classification number: C08L1/286 ,  A61L15/60 ,  B01J20/26 ,  C08L3/00 ,  C08L5/00

    Abstract: A polymer composition, a process for the production of a polymer composition, in particular of an absorbent, are disclosed which substantially consist of a special component A based on renewable polysaccharide raw materials, a special component B consisting of a water-soluble polymer, a matrix material, an ionic and/or covalent cross-linking agent, or an anti-blocking agent, which is obtainable in that the water-swellable polymer is brought together with the polysaccharide polymer, that these are dried and ground then, the other components are added, and mixing up to homogeneity is effected followed by a heat treatment, and that during the addition of the cross-linking agent, after said heat treatment, the same is optionally fixed by the matrix by means of a final heat treatment. Additionally the use of this polymer composition and (animal) hygiene items and chemico-technical products are disclosed which comprise a previously manufactured polymer composition.

    Abstract translation: PCT No.PCT / EP93 / 01062 Sec。 371日期：1995年11月3日 102（e）日期1995年11月3日PCT提交1993年5月3日PCT公布。 第WO94 / 25521号公报 日期：1994年11月10日公开了一种聚合物组合物，用于制备聚合物组合物，特别是吸收剂的方法，其基本上由基于可再生多糖原料的特殊组分A，由水组成的特殊组分B 可溶性聚合物，基质材料，离子和/或共价交联剂或防粘连剂，其可以通过使水溶胀性聚合物与多糖聚合物一起被吸收，将它们干燥和研磨 然后，加入其它组分，并进行均匀混合，然后进行热处理，并且在加入交联剂期间，在所述热处理之后，其可任选地通过基质固定 最终热处理。 此外，公开了这种聚合物组合物和（动物）卫生用品和化学技术产品的使用，其包含先前制备的聚合物组合物。

    Non-pigmented opaque jet ink compositions and methods of creating opaque indicia
    100.
    发明授权
    Non-pigmented opaque jet ink compositions and methods of creating opaque indicia 失效
    非着色不透明喷墨油墨组合物和产生不透明标记的方法

    公开(公告)号：US5710195A

    公开(公告)日：1998-01-20

    申请号：US286634

    申请日：1994-08-05

    Applicant: Ramesh B. Subbaraman ,  Barry R. Brucker

    Inventor： Ramesh B. Subbaraman ,  Barry R. Brucker

    IPC: C09D11/00 ,  C08L1/02 ,  C08L1/28

    CPC classification number: C09D11/36

    Abstract: This invention applies to methods for creating opaque indicia on substrate surfaces and to non-pigmented, moisture-free, jet ink compositions containing only solvents and solvent soluble resins and dyes that exhibit the acceptable characteristics of opacity, contrast, adhesion and machine compatibility. The compositions are on weight percentage basis as stated below. The compositions contain a combination of film forming resins of varying molecular weights of a dry resin solids percentage between 8 and 15%. The resins are chosen from the following: nitrates of cellulose; acrylics; alkyds; vinyl acetate-vinyl chloride copolymers; and styrene acrylic. The quantities of resin are chosen according to the desired viscosity, adhesion strength of film on the subject substrate and the degree of shearing of the drying resin mixture. An optimum balance of adhesion and opacity is stoichiometrically obtained. The differential solubilities of the resins in the solvent-blend is the prime moving factor of the opacifying action. The use of acid dyes and basic salts that exhibit fluorescence is considered and used in the formulations to enhance the visibility and contrast of the resultant opacified dried state of resin solids on the substrate surface. The use of specific plasticizers are another feature of this invention. Plasticizers are used in the ink jet composition to increase the flowability of the composition and also increase the tensile strength and adhesion of the ink to the substrate to which it is applied. The principle of this invention is that a water-free, multi-solvent and multi-resin jet ink which characteristically forms micro laminate miscelli and plasticizers is found to have good adhesion and opacity, and can be used to mark code and indicate non-absorbent dark substrates.

    Abstract translation: 本发明适用于在基材表面上形成不透明标记的方法和仅含有溶剂和溶剂可溶性树脂和染料的非着色无水喷墨油墨组合物的方法，其显示不透明度，对比度，粘附性和机器相容性的可接受特性。 组合物按重量百分数计，如下所述。 组合物含有干树脂固体百分比在8至15％之间的不同分子量的成膜树脂的组合。 树脂选自以下：纤维素的硝酸盐; 丙烯酸 醇酸树脂 乙酸乙烯酯 - 氯乙烯共聚物; 和苯乙烯丙烯酸。 树脂的量根据所要求的粘度，被膜基材上的膜的粘附强度和干燥树脂混合物的剪切程度来选择。 通过化学计量获得粘合和不透明度的最佳平衡。 溶剂混合物中树脂的差异溶解度是不透明作用的主要移动因素。 使用显示荧光的酸性染料和碱性盐被认为并用于制剂中，以增强所得不透明干燥状态的树脂固体在基材表面上的可视性和对比度。 使用特定的增塑剂是本发明的另一个特征。 在喷墨组合物中使用增塑剂以增加组合物的流动性，并且还增加了油墨对其所施加的基材的拉伸强度和粘附性。 本发明的原理是，发现特征性地形成微层压薄膜和增塑剂的无水，多溶剂和多树脂喷墨油具有良好的粘合性和不透明性，并且可用于标记代码并指示非吸收性 暗底。

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